BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

382 related articles for article (PubMed ID: 18692274)

  • 1. Synthesis and in vitro anti-HIV evaluation of a new series of 6-arylmethyl-substituted S-DABOs as potential non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Wang YP; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    Eur J Med Chem; 2009 Mar; 44(3):1016-23. PubMed ID: 18692274
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or alpha-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ji L; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    J Med Chem; 2007 Apr; 50(8):1778-86. PubMed ID: 17381078
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.
    Ragno R; Mai A; Sbardella G; Artico M; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; La Colla P
    J Med Chem; 2004 Feb; 47(4):928-34. PubMed ID: 14761194
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of 6-substituted 5-alkyl-2-(phenylaminocarbonylmethylthio)pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs.
    Yu M; Li Z; Liu S; Fan E; Pannecouque C; De Clercq E; Liu X
    ChemMedChem; 2011 May; 6(5):826-33. PubMed ID: 21322110
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 11: structural modulations of diaryltriazines with potent anti-HIV activity.
    Xiong YZ; Chen FE; Balzarini J; De Clercq E; Pannecouque C
    Eur J Med Chem; 2008 Jun; 43(6):1230-6. PubMed ID: 17869386
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Wang YP; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    Bioorg Med Chem; 2008 Apr; 16(7):3887-94. PubMed ID: 18267363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Non-nucleoside HIV-1 reverse-transcriptase inhibitors. Part 10. Synthesis and anti-HIV activity of 5-alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a mono- or disubstituted 2-amino function as novel 'dihydro-alkoxy-benzyl-oxopyrimidine' (DABO) analogues.
    Wang Y; Chen FE; Balzarini J; De Clercq E; Pannecouque C
    Chem Biodivers; 2008 Jan; 5(1):168-76. PubMed ID: 18205120
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nonnucleoside HIV-1 reverse transcriptase inhibitors; part 3. Synthesis and antiviral activity of 5-alkyl-2-[(aryl and alkyloxyl-carbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones.
    He Y; Chen F; Yu X; Wang Y; De Clercq E; Balzarini J; Pannecouque C
    Bioorg Chem; 2004 Dec; 32(6):536-48. PubMed ID: 15530994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of novel C5 halogen-functionalized S-DABO as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Qin H; Liu C; Guo Y; Wang R; Zhang J; Ma L; Zhang Z; Wang X; Cui Y; Liu J
    Bioorg Med Chem; 2010 May; 18(9):3231-7. PubMed ID: 20371182
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Non-nucleoside HIV reverse transcriptase inhibitors, Part 6[1]: synthesis and anti-HIV activity of novel 2-[(arylcarbonylmethyl)thio]-6-arylthio DABO analogues.
    Sun GF; Kuang YY; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    Arch Pharm (Weinheim); 2005 Oct; 338(10):457-61. PubMed ID: 16211654
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Zhang J; Zhan P; Wu J; Li Z; Jiang Y; Ge W; Pannecouque C; De Clercq E; Liu X
    Bioorg Med Chem; 2011 Jul; 19(14):4366-76. PubMed ID: 21683601
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Mai A; Sbardella G; Artico M; Ragno R; Massa S; Novellino E; Greco G; Lavecchia A; Musiu C; La Colla M; Murgioni C; La Colla P; Loddo R
    J Med Chem; 2001 Aug; 44(16):2544-54. PubMed ID: 11472208
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of 2-thioxopyrimidin-4(1H)-one derivatives as potential non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Khalifa NM; Al-Omar MA
    Int J Mol Sci; 2014 Nov; 15(11):20723-35. PubMed ID: 25397597
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of novel 2-(substituted phenylaminocarbonylmethylthio)-6-(2,6-dichlorobenzyl)-pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs.
    Yu M; Liu X; Li Z; Liu S; Pannecouque C; Clercq ED
    Bioorg Med Chem; 2009 Nov; 17(22):7749-54. PubMed ID: 19819705
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and studies of new 2-(coumarin-4-yloxy)-4,6-(substituted)-S-triazine derivatives as potential anti-HIV agents.
    Mahajan DH; Pannecouque C; De Clercq E; Chikhalia KH
    Arch Pharm (Weinheim); 2009 May; 342(5):281-90. PubMed ID: 19415671
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and anti-HIV activity evaluation of 1-[(alkenyl or alkynyl or alkyloxy)methyl]-5-alkyl-6-(1-naphthoyl)-2,4-pyrimidinediones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ji L; Chen FE; Xie B; De Clercq E; Balzarini J; Pannecouque C
    Eur J Med Chem; 2007 Feb; 42(2):198-204. PubMed ID: 17095124
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series.
    Mai A; Artico M; Sbardella G; Quartarone S; Massa S; Loi AG; De Montis A; Scintu F; Putzolu M; La Colla P
    J Med Chem; 1997 May; 40(10):1447-54. PubMed ID: 9154967
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Diverse combinatorial design, synthesis and in vitro evaluation of new HEPT analogues as potential non-nucleoside HIV-1 reverse transcription inhibitors.
    Puig-de-la-Bellacasa R; Giménez L; Pettersson S; Pascual R; Gonzalo E; Esté JA; Clotet B; Borrell JI; Teixidó J
    Eur J Med Chem; 2012 Aug; 54():159-74. PubMed ID: 22652226
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains.
    Mai A; Artico M; Rotili D; Tarantino D; Clotet-Codina I; Armand-Ugón M; Ragno R; Simeoni S; Sbardella G; Nawrozkij MB; Samuele A; Maga G; Esté JA
    J Med Chem; 2007 Nov; 50(22):5412-24. PubMed ID: 17910429
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
    Mai A; Artico M; Ragno R; Sbardella G; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; Maga G; La Colla P
    Bioorg Med Chem; 2005 Mar; 13(6):2065-77. PubMed ID: 15727860
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.