243 related articles for article (PubMed ID: 18697738)
21. Toxicity generated through inhibition of pyruvate carboxylase and carnitine palmitoyl transferase-1 is similar to high glucose/palmitate-induced glucolipotoxicity in INS-1 beta cells.
Lee JH; Jung IR; Choi SE; Lee SM; Lee SJ; Han SJ; Kim HJ; Kim DJ; Lee KW; Kang Y
Mol Cell Endocrinol; 2014 Mar; 383(1-2):48-59. PubMed ID: 24333689
[TBL] [Abstract][Full Text] [Related]
22. The MDM2-p53-pyruvate carboxylase signalling axis couples mitochondrial metabolism to glucose-stimulated insulin secretion in pancreatic β-cells.
Li X; Cheng KKY; Liu Z; Yang JK; Wang B; Jiang X; Zhou Y; Hallenborg P; Hoo RLC; Lam KSL; Ikeda Y; Gao X; Xu A
Nat Commun; 2016 Jun; 7():11740. PubMed ID: 27265727
[TBL] [Abstract][Full Text] [Related]
23. Differential contribution of pyruvate carboxylation to anaplerosis and cataplerosis during non-gluconeogenic and gluconeogenic conditions in HepG2 cells.
Wattanavanitchakorn S; Ansari IH; El Azzouny M; Longacre MJ; Stoker SW; MacDonald MJ; Jitrapakdee S
Arch Biochem Biophys; 2019 Nov; 676():108124. PubMed ID: 31585072
[TBL] [Abstract][Full Text] [Related]
24. Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion.
Macdonald MJ
Metabolism; 2003 Aug; 52(8):993-8. PubMed ID: 12898463
[TBL] [Abstract][Full Text] [Related]
25. Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.
Bao S; Bohrer A; Ramanadham S; Jin W; Zhang S; Turk J
J Biol Chem; 2006 Jan; 281(1):187-98. PubMed ID: 16286468
[TBL] [Abstract][Full Text] [Related]
26. Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity - Novel mechanistic insight from real-time analysis of oxidative phosphorylation.
Barlow J; Solomon TPJ; Affourtit C
PLoS One; 2018; 13(6):e0199505. PubMed ID: 29953508
[TBL] [Abstract][Full Text] [Related]
27. Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion.
MacDonald MJ; Brown LJ; Longacre MJ; Stoker SW; Kendrick MA; Hasan NM
Biochim Biophys Acta; 2013 Nov; 1830(11):5104-11. PubMed ID: 23876293
[TBL] [Abstract][Full Text] [Related]
28. Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion.
Macdonald MJ; Hasan NM; Longacre MJ
Biochim Biophys Acta; 2008; 1780(7-8):966-72. PubMed ID: 18439432
[TBL] [Abstract][Full Text] [Related]
29. Aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor-1{beta} plays a critical role in maintaining glucose-stimulated anaplerosis and insulin release from pancreatic {beta}-cells.
Pillai R; Huypens P; Huang M; Schaefer S; Sheinin T; Wettig SD; Joseph JW
J Biol Chem; 2011 Jan; 286(2):1014-24. PubMed ID: 21059654
[TBL] [Abstract][Full Text] [Related]
30. Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.
Zhang GF; Jensen MV; Gray SM; El K; Wang Y; Lu D; Becker TC; Campbell JE; Newgard CB
Cell Metab; 2021 Apr; 33(4):804-817.e5. PubMed ID: 33321098
[TBL] [Abstract][Full Text] [Related]
31. 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS).
Lu D; Mulder H; Zhao P; Burgess SC; Jensen MV; Kamzolova S; Newgard CB; Sherry AD
Proc Natl Acad Sci U S A; 2002 Mar; 99(5):2708-13. PubMed ID: 11880625
[TBL] [Abstract][Full Text] [Related]
32. Essential role of mitochondrial Ca2+ uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells.
Quan X; Nguyen TT; Choi SK; Xu S; Das R; Cha SK; Kim N; Han J; Wiederkehr A; Wollheim CB; Park KS
J Biol Chem; 2015 Feb; 290(7):4086-96. PubMed ID: 25548283
[TBL] [Abstract][Full Text] [Related]
33. Supplement of TCA cycle intermediates protects against high glucose/palmitate-induced INS-1 beta cell death.
Choi SE; Lee YJ; Hwang GS; Chung JH; Lee SJ; Lee JH; Han SJ; Kim HJ; Lee KW; Kim Y; Jun HS; Kang Y
Arch Biochem Biophys; 2011 Jan; 505(2):231-41. PubMed ID: 20965146
[TBL] [Abstract][Full Text] [Related]
34. Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.
Ronnebaum SM; Joseph JW; Ilkayeva O; Burgess SC; Lu D; Becker TC; Sherry AD; Newgard CB
J Biol Chem; 2008 May; 283(21):14248-56. PubMed ID: 18381287
[TBL] [Abstract][Full Text] [Related]
35. Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells.
Krus U; Kotova O; Spégel P; Hallgard E; Sharoyko VV; Vedin A; Moritz T; Sugden MC; Koeck T; Mulder H
Biochem J; 2010 Jul; 429(1):205-13. PubMed ID: 20415663
[TBL] [Abstract][Full Text] [Related]
36. Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion.
Ohsugi M; Cras-Méneur C; Zhou Y; Bernal-Mizrachi E; Johnson JD; Luciani DS; Polonsky KS; Permutt MA
J Biol Chem; 2005 Feb; 280(6):4992-5003. PubMed ID: 15546857
[TBL] [Abstract][Full Text] [Related]
37. Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling.
Brun T; Roche E; Assimacopoulos-Jeannet F; Corkey BE; Kim KH; Prentki M
Diabetes; 1996 Feb; 45(2):190-8. PubMed ID: 8549864
[TBL] [Abstract][Full Text] [Related]
38. Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis.
Christen S; Lorendeau D; Schmieder R; Broekaert D; Metzger K; Veys K; Elia I; Buescher JM; Orth MF; Davidson SM; Grünewald TG; De Bock K; Fendt SM
Cell Rep; 2016 Oct; 17(3):837-848. PubMed ID: 27732858
[TBL] [Abstract][Full Text] [Related]
39. The export of metabolites from mitochondria and anaplerosis in insulin secretion.
MacDonald MJ
Biochim Biophys Acta; 2003 Jan; 1619(1):77-88. PubMed ID: 12495818
[TBL] [Abstract][Full Text] [Related]
40. Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.
Cheng T; Sudderth J; Yang C; Mullen AR; Jin ES; Matés JM; DeBerardinis RJ
Proc Natl Acad Sci U S A; 2011 May; 108(21):8674-9. PubMed ID: 21555572
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
