These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

464 related articles for article (PubMed ID: 18697935)

  • 1. Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.
    Mahoney DJ; Cheung HH; Mrad RL; Plenchette S; Simard C; Enwere E; Arora V; Mak TW; Lacasse EC; Waring J; Korneluk RG
    Proc Natl Acad Sci U S A; 2008 Aug; 105(33):11778-83. PubMed ID: 18697935
    [TBL] [Abstract][Full Text] [Related]  

  • 2. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation.
    Varfolomeev E; Goncharov T; Fedorova AV; Dynek JN; Zobel K; Deshayes K; Fairbrother WJ; Vucic D
    J Biol Chem; 2008 Sep; 283(36):24295-9. PubMed ID: 18621737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling.
    Wang YB; Tan B; Mu R; Chang Y; Wu M; Tu HQ; Zhang YC; Guo SS; Qin XH; Li T; Li WH; Li AL; Zhang XM; Li HY
    J Biol Chem; 2015 Apr; 290(16):10395-405. PubMed ID: 25681446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IRF-1 inhibits NF-κB activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition.
    Armstrong MJ; Stang MT; Liu Y; Yan J; Pizzoferrato E; Yim JH
    Cancer Biol Ther; 2015; 16(7):1029-41. PubMed ID: 26011589
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.
    Feltham R; Moulin M; Vince JE; Mace PD; Wong WW; Anderton H; Day CL; Vaux DL; Silke J
    J Biol Chem; 2010 Jun; 285(23):17525-36. PubMed ID: 20356846
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation.
    Blackwell K; Zhang L; Workman LM; Ting AT; Iwai K; Habelhah H
    Mol Cell Biol; 2013 May; 33(10):1901-15. PubMed ID: 23459942
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TNFα induced noncanonical NF-κB activation is attenuated by RIP1 through stabilization of TRAF2.
    Kim JY; Morgan M; Kim DG; Lee JY; Bai L; Lin Y; Liu ZG; Kim YS
    J Cell Sci; 2011 Feb; 124(Pt 4):647-56. PubMed ID: 21266470
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.
    Vince JE; Chau D; Callus B; Wong WW; Hawkins CJ; Schneider P; McKinlay M; Benetatos CA; Condon SM; Chunduru SK; Yeoh G; Brink R; Vaux DL; Silke J
    J Cell Biol; 2008 Jul; 182(1):171-84. PubMed ID: 18606850
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2.
    Darding M; Feltham R; Tenev T; Bianchi K; Benetatos C; Silke J; Meier P
    Cell Death Differ; 2011 Aug; 18(8):1376-86. PubMed ID: 21331077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy.
    Lala-Tabbert N; Lejmi-Mrad R; Timusk K; Fukano M; Holbrook J; St-Jean M; LaCasse EC; Korneluk RG
    Skelet Muscle; 2019 May; 9(1):13. PubMed ID: 31126323
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.
    Vince JE; Pantaki D; Feltham R; Mace PD; Cordier SM; Schmukle AC; Davidson AJ; Callus BA; Wong WW; Gentle IE; Carter H; Lee EF; Walczak H; Day CL; Vaux DL; Silke J
    J Biol Chem; 2009 Dec; 284(51):35906-15. PubMed ID: 19815541
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TACI induces cIAP1-mediated ubiquitination of NIK by TRAF2 and TANK to limit non-canonical NF-kappaB signaling.
    Kanno Y; Sakurai D; Hase H; Kojima H; Kobata T
    J Recept Signal Transduct Res; 2010 Apr; 30(2):121-32. PubMed ID: 20184394
    [TBL] [Abstract][Full Text] [Related]  

  • 13. cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production.
    Vanlangenakker N; Vanden Berghe T; Bogaert P; Laukens B; Zobel K; Deshayes K; Vucic D; Fulda S; Vandenabeele P; Bertrand MJ
    Cell Death Differ; 2011 Apr; 18(4):656-65. PubMed ID: 21052097
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2.
    Diessenbacher P; Hupe M; Sprick MR; Kerstan A; Geserick P; Haas TL; Wachter T; Neumann M; Walczak H; Silke J; Leverkus M
    J Invest Dermatol; 2008 May; 128(5):1134-47. PubMed ID: 17989734
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis.
    Boutaffala L; Bertrand MJ; Remouchamps C; Seleznik G; Reisinger F; Janas M; Bénézech C; Fernandes MT; Marchetti S; Mair F; Ganeff C; Hupalowska A; Ricci JE; Becher B; Piette J; Knolle P; Caamano J; Vandenabeele P; Heikenwalder M; Dejardin E
    Cell Death Differ; 2015 Dec; 22(12):2020-33. PubMed ID: 26045047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Divergent effect of Birinapant, and BV6 SMAC mimetic on TNFα induced NF-κB signaling and cell viability in activated hepatic stellate cells.
    Ghufran SM; Sharma S; Ghose S; Biswas S
    Mol Biol Rep; 2023 Mar; 50(3):2107-2117. PubMed ID: 36542236
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The E3 ubiquitin ligases HOIP and cIAP1 are recruited to the TNFR2 signaling complex and mediate TNFR2-induced canonical NF-κB signaling.
    Borghi A; Haegman M; Fischer R; Carpentier I; Bertrand MJM; Libert C; Afonina IS; Beyaert R
    Biochem Pharmacol; 2018 Jul; 153():292-298. PubMed ID: 29378181
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response.
    Gardam S; Turner VM; Anderton H; Limaye S; Basten A; Koentgen F; Vaux DL; Silke J; Brink R
    Blood; 2011 Apr; 117(15):4041-51. PubMed ID: 21300983
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TRAIL activates JNK and NF-κB through RIP1-dependent and -independent pathways.
    Zhang L; Dittmer MR; Blackwell K; Workman LM; Hostager B; Habelhah H
    Cell Signal; 2015 Feb; 27(2):306-14. PubMed ID: 25446254
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are increased after labour in foetal membranes and myometrium and are essential for TNF-α-induced expression of pro-labour mediators.
    Lappas M
    Am J Reprod Immunol; 2015 Apr; 73(4):313-29. PubMed ID: 25046208
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.