BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 18701484)

  • 1. K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3.
    Shalom-Feuerstein R; Plowman SJ; Rotblat B; Ariotti N; Tian T; Hancock JF; Kloog Y
    Cancer Res; 2008 Aug; 68(16):6608-16. PubMed ID: 18701484
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity.
    Elad-Sfadia G; Haklai R; Balan E; Kloog Y
    J Biol Chem; 2004 Aug; 279(33):34922-30. PubMed ID: 15205467
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras.
    Shalom-Feuerstein R; Levy R; Makovski V; Raz A; Kloog Y
    Biochim Biophys Acta; 2008 Jun; 1783(6):985-93. PubMed ID: 18413234
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Galectin-3 promotes chronic activation of K-Ras and differentiation block in malignant thyroid carcinomas.
    Levy R; Grafi-Cohen M; Kraiem Z; Kloog Y
    Mol Cancer Ther; 2010 Aug; 9(8):2208-19. PubMed ID: 20682656
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mathematical modeling of K-Ras nanocluster formation on the plasma membrane.
    Tian T; Plowman SJ; Parton RG; Kloog Y; Hancock JF
    Biophys J; 2010 Jul; 99(2):534-43. PubMed ID: 20643072
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering.
    Blaževitš O; Mideksa YG; Šolman M; Ligabue A; Ariotti N; Nakhaeizadeh H; Fansa EK; Papageorgiou AC; Wittinghofer A; Ahmadian MR; Abankwa D
    Sci Rep; 2016 Apr; 6():24165. PubMed ID: 27087647
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells.
    Shalom-Feuerstein R; Cooks T; Raz A; Kloog Y
    Cancer Res; 2005 Aug; 65(16):7292-300. PubMed ID: 16103080
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Electrostatic interactions positively regulate K-Ras nanocluster formation and function.
    Plowman SJ; Ariotti N; Goodall A; Parton RG; Hancock JF
    Mol Cell Biol; 2008 Jul; 28(13):4377-85. PubMed ID: 18458061
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R; Piperdi S; Gorlick R
    Clin Cancer Res; 2008 Oct; 14(20):6396-404. PubMed ID: 18927278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Galectin-3 mediates cross-talk between K-Ras and Let-7c tumor suppressor microRNA.
    Levy R; Biran A; Poirier F; Raz A; Kloog Y
    PLoS One; 2011; 6(11):e27490. PubMed ID: 22102901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. H-Ras nanocluster stability regulates the magnitude of MAPK signal output.
    Rotblat B; Belanis L; Liang H; Haklai R; Elad-Zefadia G; Hancock JF; Kloog Y; Plowman SJ
    PLoS One; 2010 Aug; 5(8):e11991. PubMed ID: 20700538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Raf inhibitors target ras spatiotemporal dynamics.
    Cho KJ; Kasai RS; Park JH; Chigurupati S; Heidorn SJ; van der Hoeven D; Plowman SJ; Kusumi A; Marais R; Hancock JF
    Curr Biol; 2012 Jun; 22(11):945-55. PubMed ID: 22560614
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Galectin-1 is a novel structural component and a major regulator of h-ras nanoclusters.
    Belanis L; Plowman SJ; Rotblat B; Hancock JF; Kloog Y
    Mol Biol Cell; 2008 Apr; 19(4):1404-14. PubMed ID: 18234837
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nucleophosmin and nucleolin regulate K-Ras plasma membrane interactions and MAPK signal transduction.
    Inder KL; Lau C; Loo D; Chaudhary N; Goodall A; Martin S; Jones A; van der Hoeven D; Parton RG; Hill MM; Hancock JF
    J Biol Chem; 2009 Oct; 284(41):28410-28419. PubMed ID: 19661056
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.
    Park JI; Strock CJ; Ball DW; Nelkin BD
    Mol Cell Biol; 2003 Jan; 23(2):543-54. PubMed ID: 12509453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold.
    Posada IM; Serulla M; Zhou Y; Oetken-Lindholm C; Abankwa D; Lectez B
    PLoS One; 2016; 11(7):e0159677. PubMed ID: 27437940
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells.
    Veit C; Genze F; Menke A; Hoeffert S; Gress TM; Gierschik P; Giehl K
    Cancer Res; 2004 Aug; 64(15):5291-300. PubMed ID: 15289335
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin.
    Jeon SH; Yoon JY; Park YN; Jeong WJ; Kim S; Jho EH; Surh YJ; Choi KY
    J Biol Chem; 2007 May; 282(19):14482-92. PubMed ID: 17374607
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genetic Validation of Cell Proliferation via Ras-Independent Activation of the Raf/Mek/Erk Pathway.
    Lechuga CG; Simón-Carrasco L; Jacob HK; Drosten M
    Methods Mol Biol; 2017; 1487():269-276. PubMed ID: 27924574
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of human cystatin A by keratinocytes is positively regulated via the Ras/MEKK1/MKK7/JNK signal transduction pathway but negatively regulated via the Ras/Raf-1/MEK1/ERK pathway.
    Takahashi H; Honma M; Ishida-Yamamoto A; Namikawa K; Kiyama H; Iizuka H
    J Biol Chem; 2001 Sep; 276(39):36632-8. PubMed ID: 11451947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.