BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

640 related articles for article (PubMed ID: 18703043)

  • 1. Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells.
    Cussac D; Boutet-Robinet E; Ailhaud MC; Newman-Tancredi A; Martel JC; Danty N; Rauly-Lestienne I
    Eur J Pharmacol; 2008 Oct; 594(1-3):32-8. PubMed ID: 18703043
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of phospholipase C activity at h5-HT2C compared with h5-HT2B receptors: influence of novel ligands upon membrane-bound levels of [3H]phosphatidylinositols.
    Cussac D; Newman-Tancredi A; Quentric Y; Carpentier N; Poissonnet G; Parmentier JG; Goldstein S; Millan MJ
    Naunyn Schmiedebergs Arch Pharmacol; 2002 Mar; 365(3):242-52. PubMed ID: 11882920
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells.
    Porter RH; Benwell KR; Lamb H; Malcolm CS; Allen NH; Revell DF; Adams DR; Sheardown MJ
    Br J Pharmacol; 1999 Sep; 128(1):13-20. PubMed ID: 10498829
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. III. Agonist and antagonist properties at serotonin, 5-HT(1) and 5-HT(2), receptor subtypes.
    Newman-Tancredi A; Cussac D; Quentric Y; Touzard M; Verrièle L; Carpentier N; Millan MJ
    J Pharmacol Exp Ther; 2002 Nov; 303(2):815-22. PubMed ID: 12388668
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the same locus.
    Almaula N; Ebersole BJ; Ballesteros JA; Weinstein H; Sealfon SC
    Mol Pharmacol; 1996 Jul; 50(1):34-42. PubMed ID: 8700116
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential activation of Gq/11 and Gi(3) proteins at 5-hydroxytryptamine(2C) receptors revealed by antibody capture assays: influence of receptor reserve and relationship to agonist-directed trafficking.
    Cussac D; Newman-Tancredi A; Duqueyroix D; Pasteau V; Millan MJ
    Mol Pharmacol; 2002 Sep; 62(3):578-89. PubMed ID: 12181434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives.
    Monte AP; Waldman SR; Marona-Lewicka D; Wainscott DB; Nelson DL; Sanders-Bush E; Nichols DE
    J Med Chem; 1997 Sep; 40(19):2997-3008. PubMed ID: 9301661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of homogeneous high-affinity agonist binding assays for 5-HT2 receptor subtypes.
    Song J; Hanniford D; Doucette C; Graham E; Poole MF; Ting A; Sherf B; Harrington J; Brunden K; Stricker-Krongrad A
    Assay Drug Dev Technol; 2005 Dec; 3(6):649-59. PubMed ID: 16438660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: I. A mechanistic characterization.
    Millan MJ; Mannoury la Cour C; Chanrion B; Dupuis DS; Di Cara B; Audinot V; Cussac D; Newman-Tancredi A; Kamal M; Boutin JA; Jockers R; Marin P; Bockaert J; Muller O; Dekeyne A; Lavielle G
    J Pharmacol Exp Ther; 2012 Mar; 340(3):750-64. PubMed ID: 22178752
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation.
    Berg KA; Stout BD; Maayani S; Clarke WP
    J Pharmacol Exp Ther; 2001 Nov; 299(2):593-602. PubMed ID: 11602671
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT1 and 5-HT2 receptors.
    Watson J; Brough S; Coldwell MC; Gager T; Ho M; Hunter AJ; Jerman J; Middlemiss DN; Riley GJ; Brown AM
    Br J Pharmacol; 1998 Dec; 125(7):1413-20. PubMed ID: 9884068
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors.
    Bodenstein J; Venter DP; Brink CB
    J Pharmacol Exp Ther; 2005 Aug; 314(2):891-905. PubMed ID: 15857948
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT(2C) agonists.
    Andrews MD; Green MP; Allerton CM; Batchelor DV; Blagg J; Brown AD; Gordon DW; McMurray G; Millns DJ; Nichols CL; Watson L
    Bioorg Med Chem Lett; 2009 Sep; 19(18):5346-50. PubMed ID: 19692241
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity.
    Smith BM; Smith JM; Tsai JH; Schultz JA; Gilson CA; Estrada SA; Chen RR; Park DM; Prieto EB; Gallardo CS; Sengupta D; Thomsen WJ; Saldana HR; Whelan KT; Menzaghi F; Webb RR; Beeley NR
    Bioorg Med Chem Lett; 2005 Mar; 15(5):1467-70. PubMed ID: 15713408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of antidepressants on intracellular Ca2+ mobilization in CHO cells transfected with the human 5-HT2C receptors.
    Akiyoshi J; Isogawa K; Yamada K; Nagayama H; Fujii I
    Biol Psychiatry; 1996 Jun; 39(12):1000-8. PubMed ID: 8780834
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Position 5.46 of the serotonin 5-HT2A receptor contributes to a species-dependent variation for the 5-HT2C agonist (R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol-6(2H)-one: impact on selectivity and toxicological evaluation.
    Miller KJ; Wu GY; Varnes JG; Levesque P; Li J; Li D; Robl JA; Rossi KA; Wacker DA
    Mol Pharmacol; 2009 Dec; 76(6):1211-9. PubMed ID: 19767451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling.
    Berg KA; Dunlop J; Sanchez T; Silva M; Clarke WP
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1084-92. PubMed ID: 18065501
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacological evidence for a functional serotonin-2B receptor in a human uterine smooth muscle cell line.
    Kelly CR; Sharif NA
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1254-61. PubMed ID: 16517693
    [TBL] [Abstract][Full Text] [Related]  

  • 19. mCPP-induced hyperactivity in 5-HT2C receptor mutant mice is mediated by activation of multiple 5-HT receptor subtypes.
    Dalton GL; Lee MD; Kennett GA; Dourish CT; Clifton PG
    Neuropharmacology; 2004 Apr; 46(5):663-71. PubMed ID: 14996544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and serotonin receptor affinities of a series of trans-2-(indol-3-yl)cyclopropylamine derivatives.
    Vangveravong S; Kanthasamy A; Lucaites VL; Nelson DL; Nichols DE
    J Med Chem; 1998 Dec; 41(25):4995-5001. PubMed ID: 9836617
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.