BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 18704116)

  • 1. TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2.
    Ramesh S; Qi XJ; Wildey GM; Robinson J; Molkentin J; Letterio J; Howe PH
    EMBO Rep; 2008 Oct; 9(10):990-7. PubMed ID: 18704116
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim.
    Ramesh S; Wildey GM; Howe PH
    Cell Cycle; 2009 Jan; 8(1):11-7. PubMed ID: 19106608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes.
    Wildey GM; Patil S; Howe PH
    J Biol Chem; 2003 May; 278(20):18069-77. PubMed ID: 12637528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcriptional and post-translational regulation of Bim is essential for TGF-β and TNF-α-induced apoptosis of gastric cancer cell.
    Ha Thi HT; Lim HS; Kim J; Kim YM; Kim HY; Hong S
    Biochim Biophys Acta; 2013 Jun; 1830(6):3584-92. PubMed ID: 23500081
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells.
    Wildey GM; Howe PH
    J Biol Chem; 2009 Jul; 284(30):20227-39. PubMed ID: 19494111
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Erythropoietin-induced phosphorylation/degradation of BIM contributes to survival of erythroid cells.
    Abutin RM; Chen J; Lung TK; Lloyd JA; Sawyer ST; Harada H
    Exp Hematol; 2009 Feb; 37(2):151-8. PubMed ID: 19100675
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis.
    Ramjaun AR; Tomlinson S; Eddaoudi A; Downward J
    Oncogene; 2007 Feb; 26(7):970-81. PubMed ID: 16909112
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TGFbeta activates mitogen- and stress-activated protein kinase-1 (MSK1) to attenuate cell death.
    van der Heide LP; van Dinther M; Moustakas A; ten Dijke P
    J Biol Chem; 2011 Feb; 286(7):5003-11. PubMed ID: 21106525
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TGFbeta-mediated apoptosis of Burkitt's lymphoma BL41 cells is associated with the relocation of mitochondrial BimEL.
    Clybouw C; Mchichi BE; Hadji A; Portier A; Auffredou MT; Arnoult D; Leca G; Vazquez A
    Oncogene; 2008 May; 27(24):3446-56. PubMed ID: 18193085
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway.
    Craxton A; Draves KE; Gruppi A; Clark EA
    J Exp Med; 2005 Nov; 202(10):1363-74. PubMed ID: 16301744
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells.
    Stang SL; Lopez-Campistrous A; Song X; Dower NA; Blumberg PM; Wender PA; Stone JC
    Exp Hematol; 2009 Jan; 37(1):122-134. PubMed ID: 19100522
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation.
    O'Reilly LA; Kruse EA; Puthalakath H; Kelly PN; Kaufmann T; Huang DC; Strasser A
    J Immunol; 2009 Jul; 183(1):261-9. PubMed ID: 19542438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of Bim expression contributes to the antitumor synergy between sorafenib and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor CI-1040 in hepatocellular carcinoma.
    Ou DL; Shen YC; Liang JD; Liou JY; Yu SL; Fan HH; Wang DS; Lu YS; Hsu C; Cheng AL
    Clin Cancer Res; 2009 Sep; 15(18):5820-8. PubMed ID: 19737956
    [TBL] [Abstract][Full Text] [Related]  

  • 14. EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-delta activities.
    Quadros MR; Connelly S; Kari C; Abrams MT; Wickstrom E; Rodeck U
    Cancer Biol Ther; 2006 May; 5(5):498-504. PubMed ID: 16582597
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1.
    Rutherford C; Childs S; Ohotski J; McGlynn L; Riddick M; MacFarlane S; Tasker D; Pyne S; Pyne NJ; Edwards J; Palmer TM
    Cell Death Dis; 2013 Nov; 4(11):e927. PubMed ID: 24263101
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism.
    Zaanan A; Okamoto K; Kawakami H; Khazaie K; Huang S; Sinicrope FA
    J Biol Chem; 2015 Sep; 290(39):23838-49. PubMed ID: 26245900
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim.
    Sheridan C; Brumatti G; Martin SJ
    J Biol Chem; 2008 Aug; 283(32):22128-35. PubMed ID: 18508762
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual regulation of hepatocyte apoptosis by reactive oxygen species: Increases in transcriptional expression and decreases in proteasomal degradation of BimEL.
    Ishihara Y; Takeuchi K; Ito F; Shimamoto N
    J Cell Physiol; 2011 Apr; 226(4):1007-16. PubMed ID: 20857401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TLR-dependent Bim phosphorylation in macrophages is mediated by ERK and is connected to proteasomal degradation of the protein.
    Häcker G; Suttner K; Harada H; Kirschnek S
    Int Immunol; 2006 Dec; 18(12):1749-57. PubMed ID: 17105963
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: role of the Akt pathway and the ERK/Bim axis.
    Matsumoto T; Nagase Y; Iwasawa M; Yasui T; Masuda H; Kadono Y; Nakamura K; Tanaka S
    Arthritis Rheum; 2011 Dec; 63(12):3908-17. PubMed ID: 21898348
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.