These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

572 related articles for article (PubMed ID: 18704159)

  • 1. Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island.
    O'Hagan HM; Mohammad HP; Baylin SB
    PLoS Genet; 2008 Aug; 4(8):e1000155. PubMed ID: 18704159
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture.
    Stimson KM; Vertino PM
    J Biol Chem; 2002 Feb; 277(7):4951-8. PubMed ID: 11733524
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands.
    O'Hagan HM; Wang W; Sen S; Destefano Shields C; Lee SS; Zhang YW; Clements EG; Cai Y; Van Neste L; Easwaran H; Casero RA; Sears CL; Baylin SB
    Cancer Cell; 2011 Nov; 20(5):606-19. PubMed ID: 22094255
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters.
    Shen L; Kondo Y; Guo Y; Zhang J; Zhang L; Ahmed S; Shu J; Chen X; Waterland RA; Issa JP
    PLoS Genet; 2007 Oct; 3(10):2023-36. PubMed ID: 17967063
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation.
    Pruitt K; Zinn RL; Ohm JE; McGarvey KM; Kang SH; Watkins DN; Herman JG; Baylin SB
    PLoS Genet; 2006 Mar; 2(3):e40. PubMed ID: 16596166
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
    Yuan J; Luo RZ; Fujii S; Wang L; Hu W; Andreeff M; Pan Y; Kadota M; Oshimura M; Sahin AA; Issa JP; Bast RC; Yu Y
    Cancer Res; 2003 Jul; 63(14):4174-80. PubMed ID: 12874023
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression changes in EZH2, but not in BMI-1, SIRT1, DNMT1 or DNMT3B are associated with DNA methylation changes in prostate cancer.
    Hoffmann MJ; Engers R; Florl AR; Otte AP; Muller M; Schulz WA
    Cancer Biol Ther; 2007 Sep; 6(9):1403-12. PubMed ID: 18637271
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.
    Stirzaker C; Song JZ; Davidson B; Clark SJ
    Cancer Res; 2004 Jun; 64(11):3871-7. PubMed ID: 15172996
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage.
    Ding N; Bonham EM; Hannon BE; Amick TR; Baylin SB; O'Hagan HM
    J Mol Cell Biol; 2016 Jun; 8(3):244-54. PubMed ID: 26186941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.
    Hinshelwood RA; Melki JR; Huschtscha LI; Paul C; Song JZ; Stirzaker C; Reddel RR; Clark SJ
    Hum Mol Genet; 2009 Aug; 18(16):3098-109. PubMed ID: 19477956
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA methylation determines nucleosome occupancy in the 5'-CpG islands of tumor suppressor genes.
    Portela A; Liz J; Nogales V; SetiƩn F; Villanueva A; Esteller M
    Oncogene; 2013 Nov; 32(47):5421-8. PubMed ID: 23686312
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas.
    Rajendran G; Shanmuganandam K; Bendre A; Muzumdar D; Goel A; Shiras A
    J Neurooncol; 2011 Sep; 104(2):483-94. PubMed ID: 21229291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island.
    Zhao W; Soejima H; Higashimoto K; Nakagawachi T; Urano T; Kudo S; Matsukura S; Matsuo S; Joh K; Mukai T
    J Biochem; 2005 Mar; 137(3):431-40. PubMed ID: 15809347
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells.
    Koizume S; Tachibana K; Sekiya T; Hirohashi S; Shiraishi M
    Nucleic Acids Res; 2002 Nov; 30(21):4770-80. PubMed ID: 12409468
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA damage, homology-directed repair, and DNA methylation.
    Cuozzo C; Porcellini A; Angrisano T; Morano A; Lee B; Di Pardo A; Messina S; Iuliano R; Fusco A; Santillo MR; Muller MT; Chiariotti L; Gottesman ME; Avvedimento EV
    PLoS Genet; 2007 Jul; 3(7):e110. PubMed ID: 17616978
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter.
    Han H; Cortez CC; Yang X; Nichols PW; Jones PA; Liang G
    Hum Mol Genet; 2011 Nov; 20(22):4299-310. PubMed ID: 21835883
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers.
    Yun J; Song SH; Park J; Kim HP; Yoon YK; Lee KH; Han SW; Oh DY; Im SA; Bang YJ; Kim TY
    Lab Invest; 2012 Jul; 92(7):1033-44. PubMed ID: 22508389
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The EZH2- H3K27me3-DNMT1 complex orchestrates epigenetic silencing of the wwc1 gene, a Hippo/YAP pathway upstream effector, in breast cancer epithelial cells.
    Liu X; Li C; Zhang R; Xiao W; Niu X; Ye X; Li Z; Guo Y; Tan J; Li Y
    Cell Signal; 2018 Nov; 51():243-256. PubMed ID: 30121333
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CpG island promoter methylation and silencing of 14-3-3sigma gene expression in LNCaP and Tramp-C1 prostate cancer cell lines is associated with methyl-CpG-binding protein MBD2.
    Pulukuri SM; Rao JS
    Oncogene; 2006 Aug; 25(33):4559-72. PubMed ID: 16786000
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
    Robert MF; Morin S; Beaulieu N; Gauthier F; Chute IC; Barsalou A; MacLeod AR
    Nat Genet; 2003 Jan; 33(1):61-5. PubMed ID: 12496760
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.