BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

343 related articles for article (PubMed ID: 18706112)

  • 1. Explaining oscillations and variability in the p53-Mdm2 system.
    Proctor CJ; Gray DA
    BMC Syst Biol; 2008 Aug; 2():75. PubMed ID: 18706112
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p53-Mdm2 loop controlled by a balance of its feedback strength and effective dampening using ATM and delayed feedback.
    Wagner J; Ma L; Rice JJ; Hu W; Levine AJ; Stolovitzky GA
    Syst Biol (Stevenage); 2005 Sep; 152(3):109-18. PubMed ID: 16986275
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.
    Tang J; Agrawal T; Cheng Q; Qu L; Brewer MD; Chen J; Yang X
    PLoS One; 2013; 8(2):e55813. PubMed ID: 23405218
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of p53 stabilization by ATM after DNA damage.
    Cheng Q; Chen J
    Cell Cycle; 2010 Feb; 9(3):472-8. PubMed ID: 20081365
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A plausible model for the digital response of p53 to DNA damage.
    Ma L; Wagner J; Rice JJ; Hu W; Levine AJ; Stolovitzky GA
    Proc Natl Acad Sci U S A; 2005 Oct; 102(40):14266-71. PubMed ID: 16186499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.
    Cheng Q; Chen L; Li Z; Lane WS; Chen J
    EMBO J; 2009 Dec; 28(24):3857-67. PubMed ID: 19816404
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.
    Batchelor E; Mock CS; Bhan I; Loewer A; Lahav G
    Mol Cell; 2008 May; 30(3):277-89. PubMed ID: 18471974
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice.
    Gannon HS; Woda BA; Jones SN
    Cancer Cell; 2012 May; 21(5):668-679. PubMed ID: 22624716
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program.
    Pang LY; Scott M; Hayward RL; Mohammed H; Whitelaw CB; Smith GC; Hupp TR
    Cell Cycle; 2011 Mar; 10(6):932-50. PubMed ID: 21368573
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction.
    Wang Z; Inuzuka H; Zhong J; Fukushima H; Wan L; Liu P; Wei W
    Oncotarget; 2012 Sep; 3(9):1026-35. PubMed ID: 22976441
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.
    Khoronenkova SV; Dianova II; Ternette N; Kessler BM; Parsons JL; Dianov GL
    Mol Cell; 2012 Mar; 45(6):801-13. PubMed ID: 22361354
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A dynamic model for the p53 stress response networks under ion radiation.
    Qi JP; Shao SH; Li DD; Zhou GP
    Amino Acids; 2007 Jul; 33(1):75-83. PubMed ID: 17072789
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.
    Khosravi R; Maya R; Gottlieb T; Oren M; Shiloh Y; Shkedy D
    Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14973-7. PubMed ID: 10611322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.
    Taira N; Yamamoto H; Yamaguchi T; Miki Y; Yoshida K
    J Biol Chem; 2010 Feb; 285(7):4909-19. PubMed ID: 19965871
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A theoretical model for p53 dynamics: identifying optimal therapeutic strategy for its activation and stabilization.
    Kim DH; Rho K; Kim S
    Cell Cycle; 2009 Nov; 8(22):3707-16. PubMed ID: 19844169
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell fate decision mediated by p53 pulses.
    Zhang XP; Liu F; Cheng Z; Wang W
    Proc Natl Acad Sci U S A; 2009 Jul; 106(30):12245-50. PubMed ID: 19617533
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
    Kamijo T; van de Kamp E; Chong MJ; Zindy F; Diehl JA; Sherr CJ; McKinnon PJ
    Cancer Res; 1999 May; 59(10):2464-9. PubMed ID: 10344759
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.