BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 18716221)

  • 1. Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice.
    Hayashi Y; Yoshida M; Yamato M; Ide T; Wu Z; Ochi-Shindou M; Kanki T; Kang D; Sunagawa K; Tsutsui H; Nakanishi H
    J Neurosci; 2008 Aug; 28(34):8624-34. PubMed ID: 18716221
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of microglial mtDNA damage in age-dependent prolonged LPS-induced sickness behavior.
    Nakanishi H; Hayashi Y; Wu Z
    Neuron Glia Biol; 2011 Feb; 7(1):17-23. PubMed ID: 22032249
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice.
    Ni J; Wu Z; Stoka V; Meng J; Hayashi Y; Peters C; Qing H; Turk V; Nakanishi H
    Aging Cell; 2019 Feb; 18(1):e12856. PubMed ID: 30575263
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction.
    Ikeuchi M; Matsusaka H; Kang D; Matsushima S; Ide T; Kubota T; Fujiwara T; Hamasaki N; Takeshita A; Sunagawa K; Tsutsui H
    Circulation; 2005 Aug; 112(5):683-90. PubMed ID: 16043643
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress.
    Ikeda M; Ide T; Fujino T; Arai S; Saku K; Kakino T; Tyynismaa H; Yamasaki T; Yamada K; Kang D; Suomalainen A; Sunagawa K
    PLoS One; 2015; 10(3):e0119687. PubMed ID: 25822152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of mitochondrial transcription factor A in neural stem cells leads to immature brain development and triggers the activation of the integral stress response in vivo.
    Kuroda R; Tominaga K; Kasashima K; Kuroiwa K; Sakashita E; Hayakawa H; Kouki T; Ohno N; Kawai K; Endo H
    PLoS One; 2021; 16(7):e0255355. PubMed ID: 34320035
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice.
    Thomas RR; Khan SM; Smigrodzki RM; Onyango IG; Dennis J; Khan OM; Portelli FR; Bennett JP
    Aging (Albany NY); 2012 Sep; 4(9):620-35. PubMed ID: 23075607
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates.
    Larosche I; Choumar A; Fromenty B; Lettéron P; Abbey-Toby A; Van Remmen H; Epstein CJ; Richardson A; Feldmann G; Pessayre D; Mansouri A
    Toxicol Appl Pharmacol; 2009 Feb; 234(3):326-38. PubMed ID: 19063909
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial transcription factor A regulation of mitochondrial degeneration in experimental diabetic neuropathy.
    Chandrasekaran K; Anjaneyulu M; Inoue T; Choi J; Sagi AR; Chen C; Ide T; Russell JW
    Am J Physiol Endocrinol Metab; 2015 Jul; 309(2):E132-41. PubMed ID: 25944881
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impaired Nrf2 regulation of mitochondrial biogenesis in rostral ventrolateral medulla on hypertension induced by systemic inflammation.
    Wu KLH; Wu CW; Chao YM; Hung CY; Chan JYH
    Free Radic Biol Med; 2016 Aug; 97():58-74. PubMed ID: 27223823
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Upregulation of Mitochondrial Transcription Factor A Promotes the Repairment of Renal Tubular Epithelial Cells in Sepsis by Inhibiting Reactive Oxygen Species-Mediated Toll-Like Receptor 4/p38MAPK Signaling.
    Dai XG; Li T; Huang WB; Zeng ZH; Li Q; Yang Y; Duan ZP; Wang YJ; Ai YH
    Pathobiology; 2019; 86(5-6):263-273. PubMed ID: 31430762
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of Tfam protects mitochondria against beta-amyloid-induced oxidative damage in SH-SY5Y cells.
    Xu S; Zhong M; Zhang L; Wang Y; Zhou Z; Hao Y; Zhang W; Yang X; Wei A; Pei L; Yu Z
    FEBS J; 2009 Jul; 276(14):3800-9. PubMed ID: 19496804
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lipopolysaccharide-induced mitochondrial DNA depletion.
    Choumar A; Tarhuni A; Lettéron P; Reyl-Desmars F; Dauhoo N; Damasse J; Vadrot N; Nahon P; Moreau R; Pessayre D; Mansouri A
    Antioxid Redox Signal; 2011 Dec; 15(11):2837-54. PubMed ID: 21767162
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle.
    Konokhova Y; Spendiff S; Jagoe RT; Aare S; Kapchinsky S; MacMillan NJ; Rozakis P; Picard M; Aubertin-Leheudre M; Pion CH; Bourbeau J; Hepple RT; Taivassalo T
    Skelet Muscle; 2016; 6():10. PubMed ID: 26893822
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance.
    Zhao M; Wang Y; Li L; Liu S; Wang C; Yuan Y; Yang G; Chen Y; Cheng J; Lu Y; Liu J
    Theranostics; 2021; 11(4):1845-1863. PubMed ID: 33408785
    [No Abstract]   [Full Text] [Related]  

  • 16. Water-Soluble Arginyl-Diosgenin Analog Attenuates Hippocampal Neurogenesis Impairment Through Blocking Microglial Activation Underlying NF-κB and JNK MAPK Signaling in Adult Mice Challenged by LPS.
    Cai B; Seong KJ; Bae SW; Kook MS; Chun C; Lee JH; Choi WS; Jung JY; Kim WJ
    Mol Neurobiol; 2019 Sep; 56(9):6218-6238. PubMed ID: 30740619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice.
    Woo DK; Green PD; Santos JH; D'Souza AD; Walther Z; Martin WD; Christian BE; Chandel NS; Shadel GS
    Am J Pathol; 2012 Jan; 180(1):24-31. PubMed ID: 22056359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin.
    Thomas RR; Khan SM; Portell FR; Smigrodzki RM; Bennett JP
    Mitochondrion; 2011 Jan; 11(1):108-18. PubMed ID: 20727424
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling.
    Muhammad T; Ikram M; Ullah R; Rehman SU; Kim MO
    Nutrients; 2019 Mar; 11(3):. PubMed ID: 30884890
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial transcription factor A overexpression and base excision repair deficiency in the inner ear of rats with D-galactose-induced aging.
    Zhong Y; Hu YJ; Chen B; Peng W; Sun Y; Yang Y; Zhao XY; Fan GR; Huang X; Kong WJ
    FEBS J; 2011 Jul; 278(14):2500-10. PubMed ID: 21575134
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.