BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

368 related articles for article (PubMed ID: 18718531)

  • 1. c-Jun NH(2)-terminal kinase mediates leptin-stimulated androgen-independent prostate cancer cell proliferation via signal transducer and activator of transcription 3 and Akt.
    Miyazaki T; Bub JD; Iwamoto Y
    Biochim Biophys Acta; 2008 Oct; 1782(10):593-604. PubMed ID: 18718531
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt.
    Ogunwobi OO; Beales IL
    Int J Colorectal Dis; 2007 Apr; 22(4):401-9. PubMed ID: 16912864
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prostate cancer cell-adipocyte interaction: leptin mediates androgen-independent prostate cancer cell proliferation through c-Jun NH2-terminal kinase.
    Onuma M; Bub JD; Rummel TL; Iwamoto Y
    J Biol Chem; 2003 Oct; 278(43):42660-7. PubMed ID: 12902351
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclin-dependent kinase 5 modulates STAT3 and androgen receptor activation through phosphorylation of Ser⁷²⁷ on STAT3 in prostate cancer cells.
    Hsu FN; Chen MC; Lin KC; Peng YT; Li PC; Lin E; Chiang MC; Hsieh JT; Lin H
    Am J Physiol Endocrinol Metab; 2013 Oct; 305(8):E975-86. PubMed ID: 23941877
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells.
    Gao J; Tian J; Lv Y; Shi F; Kong F; Shi H; Zhao L
    Cancer Sci; 2009 Mar; 100(3):389-95. PubMed ID: 19154413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
    Ghosh PM; Malik SN; Bedolla RG; Wang Y; Mikhailova M; Prihoda TJ; Troyer DA; Kreisberg JI
    Endocr Relat Cancer; 2005 Mar; 12(1):119-34. PubMed ID: 15788644
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin.
    Kim YB; Uotani S; Pierroz DD; Flier JS; Kahn BB
    Endocrinology; 2000 Jul; 141(7):2328-39. PubMed ID: 10875232
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ceramide 1-phosphate stimulates macrophage proliferation through activation of the PI3-kinase/PKB, JNK and ERK1/2 pathways.
    Gangoiti P; Granado MH; Wang SW; Kong JY; Steinbrecher UP; Gómez-Muñoz A
    Cell Signal; 2008 Apr; 20(4):726-36. PubMed ID: 18234473
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.
    Beales IL; Ogunwobi O
    Mol Cell Endocrinol; 2006 Mar; 247(1-2):140-9. PubMed ID: 16442704
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combination of curcumin and bicalutamide enhanced the growth inhibition of androgen-independent prostate cancer cells through SAPK/JNK and MEK/ERK1/2-mediated targeting NF-κB/p65 and MUC1-C.
    Li J; Xiang S; Zhang Q; Wu J; Tang Q; Zhou J; Yang L; Chen Z; Hann SS
    J Exp Clin Cancer Res; 2015 May; 34(1):46. PubMed ID: 25971429
    [TBL] [Abstract][Full Text] [Related]  

  • 11. delta opioid receptors stimulate Akt-dependent phosphorylation of c-jun in T cells.
    Shahabi NA; McAllen K; Sharp BM
    J Pharmacol Exp Ther; 2006 Feb; 316(2):933-9. PubMed ID: 16249373
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the Janus-activated kinase-2-STAT3 signalling pathway in pancreatic cancer using the HSP90 inhibitor ganetespib.
    Nagaraju GP; Mezina A; Shaib WL; Landry J; El-Rayes BF
    Eur J Cancer; 2016 Jan; 52():109-19. PubMed ID: 26682870
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization.
    Gioeli D; Black BE; Gordon V; Spencer A; Kesler CT; Eblen ST; Paschal BM; Weber MJ
    Mol Endocrinol; 2006 Mar; 20(3):503-15. PubMed ID: 16282370
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components.
    Schuringa JJ; Jonk LJ; Dokter WH; Vellenga E; Kruijer W
    Biochem J; 2000 Apr; 347 Pt 1(Pt 1):89-96. PubMed ID: 10727406
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Leptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways.
    Li Z; Shen J; Wu WK; Yu X; Liang J; Qiu G; Liu J
    PLoS One; 2012; 7(12):e53176. PubMed ID: 23300886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Serotonin activates MAP kinase and PI3K/Akt signaling pathways in prostate cancer cell lines.
    Dizeyi N; Hedlund P; Bjartell A; Tinzl M; Austild-Taskén K; Abrahamsson PA
    Urol Oncol; 2011; 29(4):436-45. PubMed ID: 19926313
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer.
    Aziz MH; Manoharan HT; Church DR; Dreckschmidt NE; Zhong W; Oberley TD; Wilding G; Verma AK
    Cancer Res; 2007 Sep; 67(18):8828-38. PubMed ID: 17875724
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activation.
    Ogunwobi O; Mutungi G; Beales IL
    Endocrinology; 2006 Sep; 147(9):4505-16. PubMed ID: 16740977
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The antiproliferative effects of pterostilbene on breast cancer in vitro are via inhibition of constitutive and leptin-induced Janus kinase/signal transducer and activator of transcription activation.
    McCormack D; Schneider J; McDonald D; McFadden D
    Am J Surg; 2011 Nov; 202(5):541-4. PubMed ID: 21944294
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Leptin resistance develops spontaneously in mice during adult life in a tissue-specific manner. Consequences for hepatic steatosis.
    Stucchi P; Guzmán-Ruiz R; Gil-Ortega M; Merino B; Somoza B; Cano V; de Castro J; Sevillano J; Ramos MP; Fernández-Alfonso MS; Ruiz-Gayo M
    Biochimie; 2011 Oct; 93(10):1779-85. PubMed ID: 21740952
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.