BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 18721891)

  • 1. The JAK kinases: not just another kinase drug discovery target.
    Wilks AF
    Semin Cell Dev Biol; 2008 Aug; 19(4):319-28. PubMed ID: 18721891
    [TBL] [Abstract][Full Text] [Related]  

  • 2. JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies.
    Vainchenker W; Dusa A; Constantinescu SN
    Semin Cell Dev Biol; 2008 Aug; 19(4):385-93. PubMed ID: 18682296
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The use of structural biology in Janus kinase targeted drug discovery.
    Alicea-Velázquez NL; Boggon TJ
    Curr Drug Targets; 2011 Apr; 12(4):546-55. PubMed ID: 21126226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activating Janus kinase pseudokinase domain mutations in myeloproliferative and other blood cancers.
    Constantinescu SN; Leroy E; Gryshkova V; Pecquet C; Dusa A
    Biochem Soc Trans; 2013 Aug; 41(4):1048-54. PubMed ID: 23863177
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Janus kinases by tyrosine phosphorylation inhibitor, Tyrphostin AG-490.
    Rashid S; Bibi N; Parveen Z; Shafique S
    J Biomol Struct Dyn; 2015; 33(11):2368-79. PubMed ID: 26017266
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
    Williams NK; Bamert RS; Patel O; Wang C; Walden PM; Wilks AF; Fantino E; Rossjohn J; Lucet IS
    J Mol Biol; 2009 Mar; 387(1):219-32. PubMed ID: 19361440
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases.
    Clark JD; Flanagan ME; Telliez JB
    J Med Chem; 2014 Jun; 57(12):5023-38. PubMed ID: 24417533
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lymphoid malignancies: Another face to the Janus kinases.
    Scott LM
    Blood Rev; 2013 Mar; 27(2):63-70. PubMed ID: 23340138
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development.
    Marchais-Oberwinkler S; Henn C; Möller G; Klein T; Negri M; Oster A; Spadaro A; Werth R; Wetzel M; Xu K; Frotscher M; Hartmann RW; Adamski J
    J Steroid Biochem Mol Biol; 2011 May; 125(1-2):66-82. PubMed ID: 21193039
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The JAK and STAT family members of the mandarin fish Siniperca chuatsi: molecular cloning, tissues distribution and immunobiological activity.
    Guo CJ; Zhang YF; Yang LS; Yang XB; Wu YY; Liu D; Chen WJ; Weng SP; Yu XQ; He JG
    Fish Shellfish Immunol; 2009 Aug; 27(2):349-59. PubMed ID: 19539032
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mining for JAK-STAT mutations in cancer.
    Constantinescu SN; Girardot M; Pecquet C
    Trends Biochem Sci; 2008 Mar; 33(3):122-31. PubMed ID: 18291658
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Natural products and their derivatives regulating the janus kinase/signal transducer and activator of transcription pathway.
    Lin Y; Wang F; Zhang GL
    J Asian Nat Prod Res; 2014; 16(7):800-12. PubMed ID: 25076196
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases.
    Haan C; Behrmann I; Haan S
    J Cell Mol Med; 2010 Mar; 14(3):504-27. PubMed ID: 20132407
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Production and crystallization of recombinant JAK proteins.
    Lucet IS; Bamert R
    Methods Mol Biol; 2013; 967():275-300. PubMed ID: 23296737
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel protein kinases and molecular mechanisms of autoinhibition.
    Cheetham GM
    Curr Opin Struct Biol; 2004 Dec; 14(6):700-5. PubMed ID: 15582394
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Advances in the discovery of selective JAK inhibitors.
    Menet CJ; Rompaey LV; Geney R
    Prog Med Chem; 2013; 52():153-223. PubMed ID: 23384668
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An inhibitor of Janus kinase 2 prevents polycythemia in mice.
    Mathur A; Mo JR; Kraus M; O'Hare E; Sinclair P; Young J; Zhao S; Wang Y; Kopinja J; Qu X; Reilly J; Walker D; Xu L; Aleksandrowicz D; Marshall G; Scott ML; Kohl NE; Bachman E
    Biochem Pharmacol; 2009 Aug; 78(4):382-9. PubMed ID: 19413997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. JAK family members: Molecular cloning, expression profiles and their roles in leptin influencing lipid metabolism in Synechogobius hasta.
    Wu K; Tan XY; Xu YH; Shi X; Fan YF; Li DD; Liu X
    Comp Biochem Physiol B Biochem Mol Biol; 2017 Jan; 203():122-131. PubMed ID: 27789245
    [TBL] [Abstract][Full Text] [Related]  

  • 19. JAK2 the future: therapeutic strategies for JAK-dependent malignancies.
    LaFave LM; Levine RL
    Trends Pharmacol Sci; 2012 Nov; 33(11):574-82. PubMed ID: 22995223
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective JAK inhibitors.
    Dymock BW; Yang EG; Chu-Farseeva Y; Yao L
    Future Med Chem; 2014; 6(12):1439-71. PubMed ID: 25329199
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.