BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

459 related articles for article (PubMed ID: 18723349)

  • 41. Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors.
    Rossi C; Porcelloni M; D'Andrea P; Fincham CI; Ettorre A; Mauro S; Squarcia A; Bigioni M; Parlani M; Nardelli F; Binaschi M; Maggi CA; Fattori D
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2305-8. PubMed ID: 21420859
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents.
    Nam NH; Huong TL; Dung do TM; Dung PT; Oanh DT; Quyen D; Thao le T; Park SH; Kim KR; Han BW; Yun J; Kang JS; Kim Y; Han SB
    Eur J Med Chem; 2013; 70():477-86. PubMed ID: 24185378
    [TBL] [Abstract][Full Text] [Related]  

  • 43. A new simple and high-yield synthesis of suberoylanilide hydroxamic acid and its inhibitory effect alone or in combination with retinoids on proliferation of human prostate cancer cells.
    Gediya LK; Chopra P; Purushottamachar P; Maheshwari N; Njar VC
    J Med Chem; 2005 Jul; 48(15):5047-51. PubMed ID: 16033284
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Antiproliferative activities of a library of hybrids between indanones and HDAC inhibitor SAHA and MS-275 analogues.
    Charrier C; Roche J; Gesson JP; Bertrand P
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6142-6. PubMed ID: 17897824
    [TBL] [Abstract][Full Text] [Related]  

  • 45. New pyrrole-based histone deacetylase inhibitors: binding mode, enzyme- and cell-based investigations.
    Mai A; Valente S; Nebbioso A; Simeoni S; Ragno R; Massa S; Brosch G; De Bellis F; Manzo F; Altucci L
    Int J Biochem Cell Biol; 2009 Jan; 41(1):235-47. PubMed ID: 18834955
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Biological and biophysical properties of the histone deacetylase inhibitor suberoylanilide hydroxamic acid are affected by the presence of short alkyl groups on the phenyl ring.
    Oger F; Lecorgne A; Sala E; Nardese V; Demay F; Chevance S; Desravines DC; Aleksandrova N; Le Guével R; Lorenzi S; Beccari AR; Barath P; Hart DJ; Bondon A; Carettoni D; Simonneaux G; Salbert G
    J Med Chem; 2010 Mar; 53(5):1937-50. PubMed ID: 20143840
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma.
    Dalgard CL; Van Quill KR; O'Brien JM
    Clin Cancer Res; 2008 May; 14(10):3113-23. PubMed ID: 18483379
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Cytotoxic effects of Jay Amin hydroxamic acid (JAHA), a ferrocene-based class I histone deacetylase inhibitor, on triple-negative MDA-MB231 breast cancer cells.
    Librizzi M; Longo A; Chiarelli R; Amin J; Spencer J; Luparello C
    Chem Res Toxicol; 2012 Nov; 25(11):2608-16. PubMed ID: 23094795
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Development of hydroxamate-based histone deacetylase inhibitors containing 1,2,4-oxadiazole moiety core with antitumor activities.
    Yang F; Shan P; Zhao N; Ge D; Zhu K; Jiang CS; Li P; Zhang H
    Bioorg Med Chem Lett; 2019 Jan; 29(1):15-21. PubMed ID: 30455152
    [TBL] [Abstract][Full Text] [Related]  

  • 50. N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).
    Remiszewski SW; Sambucetti LC; Bair KW; Bontempo J; Cesarz D; Chandramouli N; Chen R; Cheung M; Cornell-Kennon S; Dean K; Diamantidis G; France D; Green MA; Howell KL; Kashi R; Kwon P; Lassota P; Martin MS; Mou Y; Perez LB; Sharma S; Smith T; Sorensen E; Taplin F; Trogani N; Versace R; Walker H; Weltchek-Engler S; Wood A; Wu A; Atadja P
    J Med Chem; 2003 Oct; 46(21):4609-24. PubMed ID: 14521422
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid.
    Kahnberg P; Lucke AJ; Glenn MP; Boyle GM; Tyndall JD; Parsons PG; Fairlie DP
    J Med Chem; 2006 Dec; 49(26):7611-22. PubMed ID: 17181145
    [TBL] [Abstract][Full Text] [Related]  

  • 52. A series of potent and selective, triazolylphenyl-based histone deacetylases inhibitors with activity against pancreatic cancer cells and Plasmodium falciparum.
    Chen Y; Lopez-Sanchez M; Savoy DN; Billadeau DD; Dow GS; Kozikowski AP
    J Med Chem; 2008 Jun; 51(12):3437-48. PubMed ID: 18494463
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.
    Dallavalle S; Cincinelli R; Nannei R; Merlini L; Morini G; Penco S; Pisano C; Vesci L; Barbarino M; Zuco V; De Cesare M; Zunino F
    Eur J Med Chem; 2009 May; 44(5):1900-12. PubMed ID: 19084294
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Synthesis and biological evaluation of triazol-4-ylphenyl-bearing histone deacetylase inhibitors as anticancer agents.
    He R; Chen Y; Chen Y; Ougolkov AV; Zhang JS; Savoy DN; Billadeau DD; Kozikowski AP
    J Med Chem; 2010 Feb; 53(3):1347-56. PubMed ID: 20055418
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Synthesis and biological characterization of the histone deacetylase inhibitor largazole and C7- modified analogues.
    Souto JA; Vaz E; Lepore I; Pöppler AC; Franci G; Alvarez R; Altucci L; de Lera AR
    J Med Chem; 2010 Jun; 53(12):4654-67. PubMed ID: 20491440
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylases for cancer treatment.
    Chen L; Wilson D; Jayaram HN; Pankiewicz KW
    J Med Chem; 2007 Dec; 50(26):6685-91. PubMed ID: 18038969
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates.
    Remiszewski SW; Sambucetti LC; Atadja P; Bair KW; Cornell WD; Green MA; Howell KL; Jung M; Kwon P; Trogani N; Walker H
    J Med Chem; 2002 Feb; 45(4):753-7. PubMed ID: 11831887
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Alkyl-substituted polyaminohydroxamic acids: a novel class of targeted histone deacetylase inhibitors.
    Varghese S; Gupta D; Baran T; Jiemjit A; Gore SD; Casero RA; Woster PM
    J Med Chem; 2005 Oct; 48(20):6350-65. PubMed ID: 16190761
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors.
    Zhang Y; Feng J; Liu C; Fang H; Xu W
    Bioorg Med Chem; 2011 Aug; 19(15):4437-44. PubMed ID: 21733698
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Structure-activity relationship and mechanistic studies for a series of cinnamyl hydroxamate histone deacetylase inhibitors.
    Tavares MT; de Almeida LC; Kronenberger T; Monteiro Ferreira G; Fujii de Divitiis T; Franco Zannini Junqueira Toledo M; Mariko Aymoto Hassimotto N; Agostinho Machado-Neto J; Veras Costa-Lotufo L; Parise-Filho R
    Bioorg Med Chem; 2021 Apr; 35():116085. PubMed ID: 33668008
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 23.