BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 18723500)

  • 1. Fatty acid synthase inhibition results in a magnetic resonance-detectable drop in phosphocholine.
    Ross J; Najjar AM; Sankaranarayanapillai M; Tong WP; Kaluarachchi K; Ronen SM
    Mol Cancer Ther; 2008 Aug; 7(8):2556-65. PubMed ID: 18723500
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic shifts induced by fatty acid synthase inhibitor orlistat in non-small cell lung carcinoma cells provide novel pharmacodynamic biomarkers for positron emission tomography and magnetic resonance spectroscopy.
    Sankaranarayanapillai M; Zhang N; Baggerly KA; Gelovani JG
    Mol Imaging Biol; 2013 Apr; 15(2):136-47. PubMed ID: 22886728
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration.
    Rossato FA; Zecchin KG; La Guardia PG; Ortega RM; Alberici LC; Costa RA; Catharino RR; Graner E; Castilho RF; Vercesi AE
    PLoS One; 2014; 9(6):e101060. PubMed ID: 24964211
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model.
    Bastos DC; Paupert J; Maillard C; Seguin F; Carvalho MA; Agostini M; Coletta RD; Noël A; Graner E
    Lab Invest; 2017 Feb; 97(2):194-206. PubMed ID: 27918556
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpression of fatty acid synthase in human gliomas correlates with the WHO tumor grade and inhibition with Orlistat reduces cell viability and triggers apoptosis.
    Grube S; Dünisch P; Freitag D; Klausnitzer M; Sakr Y; Walter J; Kalff R; Ewald C
    J Neurooncol; 2014 Jun; 118(2):277-287. PubMed ID: 24789255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis.
    Zecchin KG; Rossato FA; Raposo HF; Melo DR; Alberici LC; Oliveira HC; Castilho RF; Coletta RD; Vercesi AE; Graner E
    Lab Invest; 2011 Feb; 91(2):232-40. PubMed ID: 20805790
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of a Self-Assembled Nanoparticle Formulation of Orlistat, Nano-ORL, with Increased Cytotoxicity against Human Tumor Cell Lines.
    Hill TK; Davis AL; Wheeler FB; Kelkar SS; Freund EC; Lowther WT; Kridel SJ; Mohs AM
    Mol Pharm; 2016 Mar; 13(3):720-8. PubMed ID: 26824142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death.
    Yang CS; Matsuura K; Huang NJ; Robeson AC; Huang B; Zhang L; Kornbluth S
    Oncogene; 2015 Jun; 34(25):3264-72. PubMed ID: 25151963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fatty acid synthase inhibitor orlistat induces apoptosis in T cell lymphoma: role of cell survival regulatory molecules.
    Kant S; Kumar A; Singh SM
    Biochim Biophys Acta; 2012 Nov; 1820(11):1764-73. PubMed ID: 22877747
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of FASN reduces the synthesis of medium-chain fatty acids in goat mammary gland.
    Zhu JJ; Luo J; Wang W; Yu K; Wang HB; Shi HB; Sun YT; Lin XZ; Li J
    Animal; 2014 Sep; 8(9):1469-78. PubMed ID: 24909980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas.
    Seguin F; Carvalho MA; Bastos DC; Agostini M; Zecchin KG; Alvarez-Flores MP; Chudzinski-Tavassi AM; Coletta RD; Graner E
    Br J Cancer; 2012 Sep; 107(6):977-87. PubMed ID: 22892389
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model.
    Carvalho MA; Zecchin KG; Seguin F; Bastos DC; Agostini M; Rangel AL; Veiga SS; Raposo HF; Oliveira HC; Loda M; Coletta RD; Graner E
    Int J Cancer; 2008 Dec; 123(11):2557-65. PubMed ID: 18770866
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor growth retardation and chemosensitizing action of fatty acid synthase inhibitor orlistat on T cell lymphoma: implication of reconstituted tumor microenvironment and multidrug resistance phenotype.
    Kant S; Kumar A; Singh SM
    Biochim Biophys Acta; 2014 Jan; 1840(1):294-302. PubMed ID: 24060750
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolic consequences of treatment with AKT inhibitor perifosine in breast cancer cells.
    Su JS; Woods SM; Ronen SM
    NMR Biomed; 2012 Feb; 25(2):379-88. PubMed ID: 22253088
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?
    Lupu R; Menendez JA
    Curr Pharm Biotechnol; 2006 Dec; 7(6):483-93. PubMed ID: 17168665
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blockade of fatty acid synthase triggers significant apoptosis in mantle cell lymphoma.
    Gelebart P; Zak Z; Anand M; Belch A; Lai R
    PLoS One; 2012; 7(4):e33738. PubMed ID: 22485149
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fatty acid synthase overexpression: target for therapy and reversal of chemoresistance in ovarian cancer.
    Bauerschlag DO; Maass N; Leonhardt P; Verburg FA; Pecks U; Zeppernick F; Morgenroth A; Mottaghy FM; Tolba R; Meinhold-Heerlein I; Bräutigam K
    J Transl Med; 2015 May; 13():146. PubMed ID: 25947066
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FASN Inhibitors Enhance Bestatin-Related Tumor Cell Apoptosis Through Upregulating PEPT1.
    Ni J; Shang Y; Wang WD; Wang C; Wang AM; Li GJ; Chen SZ
    Curr Mol Pharmacol; 2023; 16(7):771-786. PubMed ID: 36411574
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy outcome.
    Yoshii Y; Furukawa T; Oyama N; Hasegawa Y; Kiyono Y; Nishii R; Waki A; Tsuji AB; Sogawa C; Wakizaka H; Fukumura T; Yoshii H; Fujibayashi Y; Lewis JS; Saga T
    PLoS One; 2013; 8(5):e64570. PubMed ID: 23741342
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical changes accompanying apoptotic cell death in retinoblastoma cancer cells treated with lipogenic enzyme inhibitors.
    Vandhana S; Coral K; Jayanthi U; Deepa PR; Krishnakumar S
    Biochim Biophys Acta; 2013 Sep; 1831(9):1458-66. PubMed ID: 23816424
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.