These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 18725387)

  • 1. YAP1 is involved in mesothelioma development and negatively regulated by Merlin through phosphorylation.
    Yokoyama T; Osada H; Murakami H; Tatematsu Y; Taniguchi T; Kondo Y; Yatabe Y; Hasegawa Y; Shimokata K; Horio Y; Hida T; Sekido Y
    Carcinogenesis; 2008 Nov; 29(11):2139-46. PubMed ID: 18725387
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma.
    Meerang M; Bérard K; Friess M; Bitanihirwe BK; Soltermann A; Vrugt B; Felley-Bosco E; Bueno R; Richards WG; Seifert B; Stahel R; Weder W; Opitz I
    Mol Oncol; 2016 Oct; 10(8):1255-65. PubMed ID: 27378628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. β1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin.
    Sabra H; Brunner M; Mandati V; Wehrle-Haller B; Lallemand D; Ribba AS; Chevalier G; Guardiola P; Block MR; Bouvard D
    J Biol Chem; 2017 Nov; 292(47):19179-19197. PubMed ID: 28972170
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis.
    Tanaka K; Osada H; Murakami-Tonami Y; Horio Y; Hida T; Sekido Y
    Cancer Lett; 2017 Jan; 385():215-224. PubMed ID: 27773750
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.
    Xiao GH; Gallagher R; Shetler J; Skele K; Altomare DA; Pestell RG; Jhanwar S; Testa JR
    Mol Cell Biol; 2005 Mar; 25(6):2384-94. PubMed ID: 15743831
    [TBL] [Abstract][Full Text] [Related]  

  • 6. YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes.
    Lorenzetto E; Brenca M; Boeri M; Verri C; Piccinin E; Gasparini P; Facchinetti F; Rossi S; Salvatore G; Massimino M; Sozzi G; Maestro R; Modena P
    Oncotarget; 2014 May; 5(9):2608-21. PubMed ID: 24810989
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Merlin/NF2-Lin28B-let-7 Is a Tumor-Suppressive Pathway that Is Cell-Density Dependent and Hippo Independent.
    Hikasa H; Sekido Y; Suzuki A
    Cell Rep; 2016 Mar; 14(12):2950-61. PubMed ID: 26997273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals.
    Zhang N; Bai H; David KK; Dong J; Zheng Y; Cai J; Giovannini M; Liu P; Anders RA; Pan D
    Dev Cell; 2010 Jul; 19(1):27-38. PubMed ID: 20643348
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Establishment and characterization of CRISPR/Cas9-mediated NF2
    Wahiduzzaman M; Karnan S; Ota A; Hanamura I; Murakami H; Inoko A; Rahman ML; Hyodo T; Konishi H; Tsuzuki S; Hosokawa Y
    Cancer Sci; 2019 Jan; 110(1):180-193. PubMed ID: 30417500
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation.
    Sekido Y
    Pathol Int; 2011 Jun; 61(6):331-44. PubMed ID: 21615608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quinidine impairs proliferation of neurofibromatosis type 2-deficient human malignant mesothelioma cells.
    Utermark T; Alekov A; Lerche H; Abramowski V; Giovannini M; Hanemann CO
    Cancer; 2003 Apr; 97(8):1955-62. PubMed ID: 12673723
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship.
    Shapiro IM; Kolev VN; Vidal CM; Kadariya Y; Ring JE; Wright Q; Weaver DT; Menges C; Padval M; McClatchey AI; Xu Q; Testa JR; Pachter JA
    Sci Transl Med; 2014 May; 6(237):237ra68. PubMed ID: 24848258
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NF2/Merlin Inactivation and Potential Therapeutic Targets in Mesothelioma.
    Sato T; Sekido Y
    Int J Mol Sci; 2018 Mar; 19(4):. PubMed ID: 29587439
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling.
    López-Lago MA; Okada T; Murillo MM; Socci N; Giancotti FG
    Mol Cell Biol; 2009 Aug; 29(15):4235-49. PubMed ID: 19451229
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Yes-associated protein 1 is activated and functions as an oncogene in meningiomas.
    Baia GS; Caballero OL; Orr BA; Lal A; Ho JS; Cowdrey C; Tihan T; Mawrin C; Riggins GJ
    Mol Cancer Res; 2012 Jul; 10(7):904-13. PubMed ID: 22618028
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hippo pathway gene mutations in malignant mesothelioma: revealed by RNA and targeted exon sequencing.
    Miyanaga A; Masuda M; Tsuta K; Kawasaki K; Nakamura Y; Sakuma T; Asamura H; Gemma A; Yamada T
    J Thorac Oncol; 2015 May; 10(5):844-851. PubMed ID: 25902174
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK.
    Poulikakos PI; Xiao GH; Gallagher R; Jablonski S; Jhanwar SC; Testa JR
    Oncogene; 2006 Sep; 25(44):5960-8. PubMed ID: 16652148
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling.
    Verma S; Yeddula N; Soda Y; Zhu Q; Pao G; Moresco J; Diedrich JK; Hong A; Plouffe S; Moroishi T; Guan KL; Verma IM
    Proc Natl Acad Sci U S A; 2019 Apr; 116(15):7363-7370. PubMed ID: 30918126
    [TBL] [Abstract][Full Text] [Related]  

  • 19. YAP1 and VGLL3, encoding two cofactors of TEAD transcription factors, are amplified and overexpressed in a subset of soft tissue sarcomas.
    Hélias-Rodzewicz Z; Pérot G; Chibon F; Ferreira C; Lagarde P; Terrier P; Coindre JM; Aurias A
    Genes Chromosomes Cancer; 2010 Dec; 49(12):1161-71. PubMed ID: 20842732
    [TBL] [Abstract][Full Text] [Related]  

  • 20. YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo.
    Sun D; Li X; He Y; Li W; Wang Y; Wang H; Jiang S; Xin Y
    Oncotarget; 2016 Dec; 7(49):81062-81076. PubMed ID: 27835600
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.