139 related articles for article (PubMed ID: 18725506)
1. Intravenous formulation of N-hydroxy-N'-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for inhibition of rat brain 20-hydroxyeicosatetraenoic acid formation.
Mu Y; Klamerus MM; Miller TM; Rohan LC; Graham SH; Poloyac SM
Drug Metab Dispos; 2008 Nov; 36(11):2324-30. PubMed ID: 18725506
[TBL] [Abstract][Full Text] [Related]
2. HET0016, a potent and selective inhibitor of 20-HETE synthesizing enzyme.
Miyata N; Taniguchi K; Seki T; Ishimoto T; Sato-Watanabe M; Yasuda Y; Doi M; Kametani S; Tomishima Y; Ueki T; Sato M; Kameo K
Br J Pharmacol; 2001 Jun; 133(3):325-9. PubMed ID: 11375247
[TBL] [Abstract][Full Text] [Related]
3. Cytochrome P450 4A isoform inhibitory profile of N-hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine (HET0016), a selective inhibitor of 20-HETE synthesis.
Seki T; Wang MH; Miyata N; Laniado-Schwartzman M
Biol Pharm Bull; 2005 Sep; 28(9):1651-4. PubMed ID: 16141533
[TBL] [Abstract][Full Text] [Related]
4. Hyperbaric oxygenation and 20-hydroxyeicosatetreanoic acid inhibition reduce stroke volume in female diabetic Sprague-Dawley rats.
Mišir M; Renić M; Novak S; Mihalj M; Ćosić A; Vesel M; Drenjančević I
Exp Physiol; 2017 Dec; 102(12):1596-1606. PubMed ID: 28940693
[TBL] [Abstract][Full Text] [Related]
5. Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia.
Poloyac SM; Zhang Y; Bies RR; Kochanek PM; Graham SH
J Cereb Blood Flow Metab; 2006 Dec; 26(12):1551-61. PubMed ID: 16570075
[TBL] [Abstract][Full Text] [Related]
6. 20-Hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries.
Orozco LD; Liu H; Perkins E; Johnson DA; Chen BB; Fan F; Baker RC; Roman RJ
J Pharmacol Exp Ther; 2013 Jul; 346(1):67-74. PubMed ID: 23658377
[TBL] [Abstract][Full Text] [Related]
7. Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor.
Yang ZJ; Carter EL; Kibler KK; Kwansa H; Crafa DA; Martin LJ; Roman RJ; Harder DR; Koehler RC
J Neurochem; 2012 Apr; 121(1):168-79. PubMed ID: 22251169
[TBL] [Abstract][Full Text] [Related]
8. The role of 20-hydroxyeicosatetraenoic acid in adrenocorticotrophic hormone and dexamethasone-induced hypertension.
Zhang Y; Wu JH; Vickers JJ; Ong SL; Temple SE; Mori TA; Croft KD; Whitworth JA
J Hypertens; 2009 Aug; 27(8):1609-16. PubMed ID: 19458537
[TBL] [Abstract][Full Text] [Related]
9. Inhibitors of 20-HETE formation promote salt-sensitive hypertension in rats.
Hoagland KM; Flasch AK; Roman RJ
Hypertension; 2003 Oct; 42(4):669-73. PubMed ID: 12874093
[TBL] [Abstract][Full Text] [Related]
10. Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A.
Guo M; Roman RJ; Falck JR; Edwards PA; Scicli AG
J Pharmacol Exp Ther; 2005 Nov; 315(2):526-33. PubMed ID: 16081682
[TBL] [Abstract][Full Text] [Related]
11. The protective effect of HET0016 on brain edema and blood-brain barrier dysfunction after cerebral ischemia/reperfusion.
Liu Y; Wang D; Wang H; Qu Y; Xiao X; Zhu Y
Brain Res; 2014 Jan; 1544():45-53. PubMed ID: 24316243
[TBL] [Abstract][Full Text] [Related]
12. 9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N'-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A.
Guo M; Roman RJ; Fenstermacher JD; Brown SL; Falck JR; Arbab AS; Edwards PA; Scicli AG
J Pharmacol Exp Ther; 2006 Apr; 317(1):97-108. PubMed ID: 16352703
[TBL] [Abstract][Full Text] [Related]
13. Administration of a 20-Hydroxyeicosatetraenoic Acid Synthesis Inhibitor Improves Outcome in a Rat Model of Pediatric Traumatic Brain Injury.
Shu S; Zhang Z; Spicer D; Kulikowicz E; Hu K; Babapoor-Farrokhran S; Kannan S; Koehler RC; Robertson CL
Dev Neurosci; 2019; 41(3-4):166-176. PubMed ID: 31553983
[TBL] [Abstract][Full Text] [Related]
14. Treatment with the cytochrome P450 ω-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.
Toth P; Csiszar A; Sosnowska D; Tucsek Z; Cseplo P; Springo Z; Tarantini S; Sonntag WE; Ungvari Z; Koller A
Br J Pharmacol; 2013 Apr; 168(8):1878-88. PubMed ID: 23194285
[TBL] [Abstract][Full Text] [Related]
15. Discovery of a N'-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor.
Sato M; Ishii T; Kobayashi-Matsunaga Y; Amada H; Taniguchi K; Miyata N; Kameo K
Bioorg Med Chem Lett; 2001 Dec; 11(23):2993-5. PubMed ID: 11714595
[TBL] [Abstract][Full Text] [Related]
16. Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats.
Dunn KM; Renic M; Flasch AK; Harder DR; Falck J; Roman RJ
Am J Physiol Heart Circ Physiol; 2008 Dec; 295(6):H2455-65. PubMed ID: 18952718
[TBL] [Abstract][Full Text] [Related]
17. Interaction of nitric oxide, 20-HETE, and EETs during functional hyperemia in whisker barrel cortex.
Liu X; Li C; Falck JR; Roman RJ; Harder DR; Koehler RC
Am J Physiol Heart Circ Physiol; 2008 Aug; 295(2):H619-31. PubMed ID: 18502903
[TBL] [Abstract][Full Text] [Related]
18. Selective inhibition of 20-hydroxyeicosatetraenoic acid lowers blood pressure in a rat model of preeclampsia.
Faulkner JL; Plenty NL; Wallace K; Amaral LM; Cunningham MW; Murphy S; LaMarca B
Prostaglandins Other Lipid Mediat; 2018 Jan; 134():108-113. PubMed ID: 28951260
[TBL] [Abstract][Full Text] [Related]
19. Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.
Renic M; Kumar SN; Gebremedhin D; Florence MA; Gerges NZ; Falck JR; Harder DR; Roman RJ
Am J Physiol Heart Circ Physiol; 2012 Mar; 302(6):H1285-93. PubMed ID: 22245774
[TBL] [Abstract][Full Text] [Related]
20. Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition.
Zhang Y; Hoda MN; Zheng X; Li W; Luo P; Maddipati KR; Seki T; Ergul A; Wang MH
Am J Physiol Regul Integr Comp Physiol; 2014 Sep; 307(6):R693-703. PubMed ID: 24990856
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
