BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 1872947)

  • 41. Novel DNA-directed alkylating agents consisting of naphthalimide, nitrogen mustard and lexitropsin moieties: synthesis, DNA sequence specificity and biological evaluation.
    Gupta R; Liu J; Xie G; Lown JW
    Anticancer Drug Des; 1996 Dec; 11(8):581-96. PubMed ID: 9022747
    [TBL] [Abstract][Full Text] [Related]  

  • 42. [Aromatic N-mustard compounds. 1. Derivatives of 3-N, N-bis-(2-chlorethyl)amino-4-methylbenzoid acid].
    Cambanis A; Gericke D
    Arzneimittelforschung; 1975 Jan; 25(1):1-9. PubMed ID: 1173761
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.
    Kapuriya N; Kapuriya K; Zhang X; Chou TC; Kakadiya R; Wu YT; Tsai TH; Chen YT; Lee TC; Shah A; Naliapara Y; Su TL
    Bioorg Med Chem; 2008 May; 16(10):5413-23. PubMed ID: 18450456
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Chemical structure of carbamoylating groups and their relationship to bone marrow toxicity and antiglioma activity of bifunctionally alkylating and carbamoylating nitrosoureas.
    Ali-Osman F; Giblin J; Berger M; Murphy MJ; Rosenblum ML
    Cancer Res; 1985 Sep; 45(9):4185-91. PubMed ID: 2411398
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Design, synthesis, and anti-tumor evaluation of novel symmetrical bis-benzimidazoles.
    Yang YH; Cheng MS; Wang QH; Nie H; Liao N; Wang J; Chen H
    Eur J Med Chem; 2009 Apr; 44(4):1808-12. PubMed ID: 18762358
    [TBL] [Abstract][Full Text] [Related]  

  • 46. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
    Smaill JB; Fan JY; Denny WA
    Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Sensitivity of human cell strains having different abilities to repair O6-methylguanine in DNA to inactivation by alkylating agents including chloroethylnitrosoureas.
    Scudiero DA; Meyer SA; Clatterbuck BE; Mattern MR; Ziolkowski CH; Day RS
    Cancer Res; 1984 Jun; 44(6):2467-74. PubMed ID: 6722789
    [TBL] [Abstract][Full Text] [Related]  

  • 48. In vitro and in vivo activity of 1-aryl-3-(2-chloroethyl) urea derivatives as new antineoplastic agents.
    Lacroix J; Gaudreault RC; Pagé M; Joly LP
    Anticancer Res; 1988; 8(4):595-8. PubMed ID: 3052247
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Synthesis and anticancer activity of 5-diethylaminomethyl derivatives and nitrogen mustards of uracil and 2-thiouracils.
    Fabrissin S; de Nardo M; Nisi C; Morasca L; Dolfini E; Franchi G
    J Med Chem; 1976 May; 19(5):639-42. PubMed ID: 1271405
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Synthesis and in vitro evaluation of macromolecular antitumour derivatives based on phenylenediamine mustard.
    De Winne K; Seymour LW; Schacht EH
    Eur J Pharm Sci; 2005 Feb; 24(2-3):159-68. PubMed ID: 15661487
    [TBL] [Abstract][Full Text] [Related]  

  • 51. A novel kind of antitumour drugs using sulfonamide as parent compound.
    Huang Z; Lin Z; Huang J
    Eur J Med Chem; 2001; 36(11-12):863-72. PubMed ID: 11755229
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Research on compounds with antiblastic activity. XL. Synthesis of 3-p-(2',5'-dimethoxy-4'-(N,N-bis-( -chloroethyl)-amino)benzylideneamino)phenyl-2-oxazolidinone (GEA 29 ; BAY a 5850) and its analogues.
    Artico M; De Martino G; Giuliano R
    Farmaco Sci; 1971 Sep; 26(9):771-83. PubMed ID: 5157545
    [No Abstract]   [Full Text] [Related]  

  • 53. Synthesis and evaluation of DNA-targeted spatially separated bis(aniline mustards) as potential alkylating agents with enhanced DNA cross-linking capability.
    Gourdie TA; Prakash AS; Wakelin LP; Woodgate PD; Denny WA
    J Med Chem; 1991 Jan; 34(1):240-8. PubMed ID: 1992124
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Hypoxia-selective antitumor agents. 7. Metal complexes of aliphatic mustards as a new class of hypoxia-selective cytotoxins. Synthesis and evaluation of cobalt(III) complexes of bidentate mustards.
    Ware DC; Palmer BD; Wilson WR; Denny WA
    J Med Chem; 1993 Jun; 36(13):1839-46. PubMed ID: 8515422
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Synthesis and DNA cleavage activity of Bis-3-chloropiperidines as alkylating agents.
    Zuravka I; Roesmann R; Sosic A; Wende W; Pingoud A; Gatto B; Göttlich R
    ChemMedChem; 2014 Sep; 9(9):2178-85. PubMed ID: 24616300
    [TBL] [Abstract][Full Text] [Related]  

  • 56. [Design, synthesis and anti-proliferative activity of novel coumarin derivatives linking Schiff base and aryl nitrogen mustard].
    Liu WH; Wang SB; Chang JX; Liu Y
    Yao Xue Xue Bao; 2014 Feb; 49(2):217-24. PubMed ID: 24761612
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Nitrogen mustards derived from alpha-hydroxymethyleneketones.
    Mariani E; Tasca A; Bignardi G; Schenone P
    Farmaco Sci; 1978 Aug; 33(8):612-7. PubMed ID: 744257
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Steroidal esters of the aromatic nitrogen mustard 2-[4-N,N-bis(2-chloroethyl)amino-phenyl]butanoic acid (2-PHE-BU): synthesis and in-vivo biological evaluation.
    Papaconstantinou IC; Fousteris MA; Koutsourea AI; Pairas GN; Papageorgiou AD; Nikolaropoulos SS
    Anticancer Drugs; 2013 Jan; 24(1):52-65. PubMed ID: 23187313
    [TBL] [Abstract][Full Text] [Related]  

  • 59. N-(2-chloroethyl)-N-(2-hydroxyethyl)arylamines. Possible intermediates to potential carcinolytic agents bearing dissimilar reactive functions.
    Foster AB; Jarman M; Ross WC; Tisdale MJ
    J Med Chem; 1972 Aug; 15(8):869-70. PubMed ID: 5044312
    [No Abstract]   [Full Text] [Related]  

  • 60. Isoquinolines. 6. Potential central nervous system antitumor agents. Nitrogen mustards of 3-amino-4-(p-aminophenyl)isoquinoline.
    Filer CN; Granchelli FE; Soloway AH; Neumeyer JL
    J Med Chem; 1977 Nov; 20(11):1504-8. PubMed ID: 915914
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.