BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

363 related articles for article (PubMed ID: 18753132)

  • 1. DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility.
    Maillet M; Purcell NH; Sargent MA; York AJ; Bueno OF; Molkentin JD
    J Biol Chem; 2008 Nov; 283(45):31246-55. PubMed ID: 18753132
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5.
    Arkell RS; Dickinson RJ; Squires M; Hayat S; Keyse SM; Cook SJ
    Cell Signal; 2008 May; 20(5):836-43. PubMed ID: 18280112
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mice lacking DUSP6/8 have enhanced ERK1/2 activity and resistance to diet-induced obesity.
    Liu R; Peters M; Urban N; Knowlton J; Napierala T; Gabrysiak J
    Biochem Biophys Res Commun; 2020 Nov; 533(1):17-22. PubMed ID: 32917360
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential expression profiles and roles of inducible DUSPs and ERK1/2-specific constitutive DUSP6 and DUSP7 in microglia.
    Ham JE; Oh EK; Kim DH; Choi SH
    Biochem Biophys Res Commun; 2015 Nov; 467(2):254-60. PubMed ID: 26435497
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MKP3 negatively modulates PDGF-induced Akt and Erk5 phosphorylation as well as chemotaxis.
    Razmara M; Eger G; Rorsman C; Heldin CH; Lennartsson J
    Cell Signal; 2012 Mar; 24(3):635-40. PubMed ID: 22100392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells.
    Sarközi R; Miller B; Pollack V; Feifel E; Mayer G; Sorokin A; Schramek H
    J Cell Physiol; 2007 Apr; 211(1):88-100. PubMed ID: 17131384
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo.
    Purcell NH; Wilkins BJ; York A; Saba-El-Leil MK; Meloche S; Robbins J; Molkentin JD
    Proc Natl Acad Sci U S A; 2007 Aug; 104(35):14074-9. PubMed ID: 17709754
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitogen-activated protein kinase (MAPK) phosphatase 3-mediated cross-talk between MAPKs ERK2 and p38alpha.
    Zhang YY; Wu JW; Wang ZX
    J Biol Chem; 2011 May; 286(18):16150-62. PubMed ID: 21454500
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Caspase-3 cleavage of DUSP6/MKP3 at the interdomain region generates active MKP3 fragments that regulate ERK1/2 subcellular localization and function.
    Cejudo-Marín R; Tárrega C; Nunes-Xavier CE; Pulido R
    J Mol Biol; 2012 Jun; 420(1-2):128-38. PubMed ID: 22504224
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.
    Ekerot M; Stavridis MP; Delavaine L; Mitchell MP; Staples C; Owens DM; Keenan ID; Dickinson RJ; Storey KG; Keyse SM
    Biochem J; 2008 Jun; 412(2):287-98. PubMed ID: 18321244
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth.
    Kehat I; Davis J; Tiburcy M; Accornero F; Saba-El-Leil MK; Maillet M; York AJ; Lorenz JN; Zimmermann WH; Meloche S; Molkentin JD
    Circ Res; 2011 Jan; 108(2):176-83. PubMed ID: 21127295
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disinhibition of the extracellular-signal-regulated kinase restores the amplification of circadian rhythms by lithium in cells from bipolar disorder patients.
    McCarthy MJ; Wei H; Landgraf D; Le Roux MJ; Welsh DK
    Eur Neuropsychopharmacol; 2016 Aug; 26(8):1310-9. PubMed ID: 27216486
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dual-specificity phosphatase 6 (Dusp6), a negative regulator of FGF2/ERK1/2 signaling, enhances 17β-estradiol-induced cell growth in endometrial adenocarcinoma cell.
    Zhang H; Guo Q; Wang C; Yan L; Fu Y; Fan M; Zhao X; Li M
    Mol Cell Endocrinol; 2013 Aug; 376(1-2):60-9. PubMed ID: 23419500
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitogen-Activated Protein Kinases and Hypoxic/Ischemic Nephropathy.
    Luo F; Shi J; Shi Q; Xu X; Xia Y; He X
    Cell Physiol Biochem; 2016; 39(3):1051-67. PubMed ID: 27544204
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p38-MAP Kinase Negatively Regulates the Slow Force Response to Stretch in Rat Myocardium through the Up-Regulation of Dual Specificity Phosphatase 6 (DUSP6).
    Zavala MR; Díaz RG; Medina AJ; Acosta MP; Escudero DS; Ennis IL; Pérez NG; Villa-Abrille MC
    Cell Physiol Biochem; 2019; 52(2):172-185. PubMed ID: 30816666
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DUSP6/MKP3 is overexpressed in papillary and poorly differentiated thyroid carcinoma and contributes to neoplastic properties of thyroid cancer cells.
    Degl'Innocenti D; Romeo P; Tarantino E; Sensi M; Cassinelli G; Catalano V; Lanzi C; Perrone F; Pilotti S; Seregni E; Pierotti MA; Greco A; Borrello MG
    Endocr Relat Cancer; 2013 Feb; 20(1):23-37. PubMed ID: 23132790
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cisplatin-mediated activation of extracellular signal-regulated kinases 1/2 (ERK1/2) by inhibition of ERK1/2 phosphatases.
    Gozdz A; Vashishta A; Kalita K; Szatmari E; Zheng JJ; Tamiya S; Delamere NA; Hetman M
    J Neurochem; 2008 Sep; 106(5):2056-67. PubMed ID: 18665890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ERK1/2, but not ERK5, is necessary and sufficient for phosphorylation and activation of c-Fos.
    Gilley R; March HN; Cook SJ
    Cell Signal; 2009 Jun; 21(6):969-77. PubMed ID: 19249353
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
    Auger-Messier M; Accornero F; Goonasekera SA; Bueno OF; Lorenz JN; van Berlo JH; Willette RN; Molkentin JD
    Circ Res; 2013 Jan; 112(1):48-56. PubMed ID: 22993413
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility.
    Szokodi I; Kerkelä R; Kubin AM; Sármán B; Pikkarainen S; Kónyi A; Horváth IG; Papp L; Tóth M; Skoumal R; Ruskoaho H
    Circulation; 2008 Oct; 118(16):1651-8. PubMed ID: 18824646
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.