BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 18755184)

  • 61. Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis.
    McGee TP; Cheng HH; Kumagai H; Omura S; Simoni RD
    J Biol Chem; 1996 Oct; 271(41):25630-8. PubMed ID: 8810339
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Capsaicin-induced apoptosis is regulated by endoplasmic reticulum stress- and calpain-mediated mitochondrial cell death pathways.
    Lee MJ; Kee KH; Suh CH; Lim SC; Oh SH
    Toxicology; 2009 Oct; 264(3):205-14. PubMed ID: 19699254
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Effects of tocotrienol on the intracellular translocation and degradation of apolipoprotein B: possible involvement of a proteasome independent pathway.
    Wang Q; Theriault A; Gapor A; Adeli K
    Biochem Biophys Res Commun; 1998 May; 246(3):640-3. PubMed ID: 9618265
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Kinetics of ferric cytochrome P450 reduction by NADPH-cytochrome P450 reductase: rapid reduction in the absence of substrate and variations among cytochrome P450 systems.
    Guengerich FP; Johnson WW
    Biochemistry; 1997 Dec; 36(48):14741-50. PubMed ID: 9398194
    [TBL] [Abstract][Full Text] [Related]  

  • 65. In vitro biotransformation of a novel antimalarial cysteine protease inhibitor in human liver microsomes.
    Zhang Y; Guo X; Lin ET; Benet LZ
    Pharmacology; 1999 Mar; 58(3):147-59. PubMed ID: 9925971
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Substitutions in the C-terminal portion of the catalytic domain partially reverse assembly defects introduced by mutations in the N-terminal linker sequence of cytochrome P450 2C2.
    Doray B; Chen CD; Kemper B
    Biochemistry; 1999 Sep; 38(37):12180-6. PubMed ID: 10508423
    [TBL] [Abstract][Full Text] [Related]  

  • 67. A novel quality control compartment derived from the endoplasmic reticulum.
    Kamhi-Nesher S; Shenkman M; Tolchinsky S; Fromm SV; Ehrlich R; Lederkremer GZ
    Mol Biol Cell; 2001 Jun; 12(6):1711-23. PubMed ID: 11408579
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation.
    Waithe D; Ferron L; Page KM; Chaggar K; Dolphin AC
    J Biol Chem; 2011 Mar; 286(11):9598-611. PubMed ID: 21233207
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Engineering human cytochrome P450 enzymes into catalytically self-sufficient chimeras using molecular Lego.
    Dodhia VR; Fantuzzi A; Gilardi G
    J Biol Inorg Chem; 2006 Oct; 11(7):903-16. PubMed ID: 16862439
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Hepatic cytochrome P450 degradation: mechanistic diversity of the cellular sanitation brigade.
    Correia MA
    Drug Metab Rev; 2003; 35(2-3):107-43. PubMed ID: 12959413
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Inhibition of rat and human cytochrome P4502E1 catalytic activity and reactive oxygen radical formation by nitric oxide.
    Gergel D; Misík V; Riesz P; Cederbaum AI
    Arch Biochem Biophys; 1997 Jan; 337(2):239-50. PubMed ID: 9016819
    [TBL] [Abstract][Full Text] [Related]  

  • 72. The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells.
    Rui YN; Xu Z; Chen Z; Zhang S
    Autophagy; 2015; 11(5):812-32. PubMed ID: 25984893
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Hormone- and substrate-regulated intracellular degradation of cytochrome P450 (2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes.
    Eliasson E; Mkrtchian S; Ingelman-Sundberg M
    J Biol Chem; 1992 Aug; 267(22):15765-9. PubMed ID: 1639811
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Ubiquitin-dependent and -independent proteasomal degradation of apoB associated with endoplasmic reticulum and Golgi apparatus, respectively, in HepG2 cells.
    Liao W; Chang BH; Mancini M; Chan L
    J Cell Biochem; 2003 Aug; 89(5):1019-29. PubMed ID: 12874835
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells.
    Ustundag Y; Bronk SF; Gores GJ
    World J Gastroenterol; 2007 Feb; 13(6):851-7. PubMed ID: 17352013
    [TBL] [Abstract][Full Text] [Related]  

  • 76. High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein.
    Fisher CW; Shet MS; Caudle DL; Martin-Wixtrom CA; Estabrook RW
    Proc Natl Acad Sci U S A; 1992 Nov; 89(22):10817-21. PubMed ID: 1438282
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops.
    Castrignanò S; D'Avino S; Di Nardo G; Catucci G; Sadeghi SJ; Gilardi G
    Biochim Biophys Acta Proteins Proteom; 2018 Jan; 1866(1):116-125. PubMed ID: 28734977
    [TBL] [Abstract][Full Text] [Related]  

  • 78. A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation.
    Wang Y; Liao M; Hoe N; Acharya P; Deng C; Krutchinsky AN; Correia MA
    J Biol Chem; 2009 Feb; 284(9):5671-84. PubMed ID: 19095658
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines: application of genetically engineered Salmonella typhimurium YG7108 expressing each form of CYP together with human NADPH-cytochrome P450 reductase.
    Fujita K; Kamataki T
    Mutat Res; 2001 Nov; 483(1-2):35-41. PubMed ID: 11600130
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-Ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance.
    Kwon D; Kim SM; Jacob P; Liu Y; Correia MA
    Mol Pharmacol; 2019 Nov; 96(5):641-654. PubMed ID: 31492698
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.