These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer. Julian E; Hallahan AR; Wainwright BJ Neural Dev; 2010 Oct; 5():27. PubMed ID: 20950430 [TBL] [Abstract][Full Text] [Related]
4. miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse. Woods S; Barter MJ; Elliott HR; McGillivray CM; Birch MA; Clark IM; Young DA Matrix Biol; 2019 Apr; 77():87-100. PubMed ID: 30193893 [TBL] [Abstract][Full Text] [Related]
5. Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1. Götschel F; Berg D; Gruber W; Bender C; Eberl M; Friedel M; Sonntag J; Rüngeler E; Hache H; Wierling C; Nietfeld W; Lehrach H; Frischauf A; Schwartz-Albiez R; Aberger F; Korf U PLoS One; 2013; 8(6):e65403. PubMed ID: 23762360 [TBL] [Abstract][Full Text] [Related]
6. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. Long J; Li B; Rodriguez-Blanco J; Pastori C; Volmar CH; Wahlestedt C; Capobianco A; Bai F; Pei XH; Ayad NG; Robbins DJ J Biol Chem; 2014 Dec; 289(51):35494-502. PubMed ID: 25355313 [TBL] [Abstract][Full Text] [Related]
7. β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells. Miele E; Po A; Begalli F; Antonucci L; Mastronuzzi A; Marras CE; Carai A; Cucchi D; Abballe L; Besharat ZM; Catanzaro G; Infante P; Di Marcotullio L; Canettieri G; De Smaele E; Screpanti I; Locatelli F; Ferretti E BMC Cancer; 2017 Jul; 17(1):488. PubMed ID: 28716052 [TBL] [Abstract][Full Text] [Related]
8. RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling. Shimokawa T; Rahman MF; Tostar U; Sonkoly E; Ståhle M; Pivarcsi A; Palaniswamy R; Zaphiropoulos PG RNA Biol; 2013 Feb; 10(2):321-33. PubMed ID: 23324600 [TBL] [Abstract][Full Text] [Related]
9. Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination. Di Marcotullio L; Ferretti E; Greco A; De Smaele E; Po A; Sico MA; Alimandi M; Giannini G; Maroder M; Screpanti I; Gulino A Nat Cell Biol; 2006 Dec; 8(12):1415-23. PubMed ID: 17115028 [TBL] [Abstract][Full Text] [Related]
10. Mechanisms of Hedgehog signalling in cancer. Marini KD; Payne BJ; Watkins DN; Martelotto LG Growth Factors; 2011 Dec; 29(6):221-34. PubMed ID: 21875383 [TBL] [Abstract][Full Text] [Related]
11. The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway. Scicchitano S; Giordano M; Lucchino V; Montalcini Y; Chiarella E; Aloisio A; Codispoti B; Zoppoli P; Melocchi V; Bianchi F; De Smaele E; Mesuraca M; Morrone G; Bond HM Cell Death Dis; 2019 Sep; 10(10):715. PubMed ID: 31558698 [TBL] [Abstract][Full Text] [Related]
12. Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth. Di Magno L; Manzi D; D'Amico D; Coni S; Macone A; Infante P; Di Marcotullio L; De Smaele E; Ferretti E; Screpanti I; Agostinelli E; Gulino A; Canettieri G Cell Cycle; 2014; 13(21):3404-13. PubMed ID: 25485584 [TBL] [Abstract][Full Text] [Related]
13. Hedgehog pathway permissive conditions allow generation of immortal cell lines from granule cells derived from cancerous and non-cancerous cerebellum. Heil C Open Biol; 2019 Jan; 9(1):180145. PubMed ID: 30958113 [TBL] [Abstract][Full Text] [Related]
14. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors. Northcott PA; Fernandez-L A; Hagan JP; Ellison DW; Grajkowska W; Gillespie Y; Grundy R; Van Meter T; Rutka JT; Croce CM; Kenney AM; Taylor MD Cancer Res; 2009 Apr; 69(8):3249-55. PubMed ID: 19351822 [TBL] [Abstract][Full Text] [Related]
15. An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma. De Smaele E; Fragomeli C; Ferretti E; Pelloni M; Po A; Canettieri G; Coni S; Di Marcotullio L; Greco A; Moretti M; Di Rocco C; Pazzaglia S; Maroder M; Screpanti I; Giannini G; Gulino A Neoplasia; 2008 Jan; 10(1):89-98. PubMed ID: 18231642 [TBL] [Abstract][Full Text] [Related]
16. Histone acetyltransferase PCAF is required for Hedgehog-Gli-dependent transcription and cancer cell proliferation. Malatesta M; Steinhauer C; Mohammad F; Pandey DP; Squatrito M; Helin K Cancer Res; 2013 Oct; 73(20):6323-33. PubMed ID: 23943798 [TBL] [Abstract][Full Text] [Related]
17. REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma. Di Marcotullio L; Ferretti E; De Smaele E; Argenti B; Mincione C; Zazzeroni F; Gallo R; Masuelli L; Napolitano M; Maroder M; Modesti A; Giangaspero F; Screpanti I; Alesse E; Gulino A Proc Natl Acad Sci U S A; 2004 Jul; 101(29):10833-8. PubMed ID: 15249678 [TBL] [Abstract][Full Text] [Related]
18. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line. Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979 [TBL] [Abstract][Full Text] [Related]
19. Identifying hedgehog signaling specific microRNAs in glioblastomas. Gu W; Shou J; Gu S; Sun B; Che X Int J Med Sci; 2014; 11(5):488-93. PubMed ID: 24688313 [TBL] [Abstract][Full Text] [Related]
20. LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway. Zhuang Z; Wang K; Cheng X; Qu X; Jiang B; Li Z; Luo J; Shao Z; Duan T PLoS One; 2013; 8(7):e67431. PubMed ID: 23861764 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]