342 related articles for article (PubMed ID: 18757750)
1. The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning.
Wilson DN; Schluenzen F; Harms JM; Starosta AL; Connell SR; Fucini P
Proc Natl Acad Sci U S A; 2008 Sep; 105(36):13339-44. PubMed ID: 18757750
[TBL] [Abstract][Full Text] [Related]
2. Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin.
Harms JM; Schlünzen F; Fucini P; Bartels H; Yonath A
BMC Biol; 2004 Apr; 2():4. PubMed ID: 15059283
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics.
Tsai K; Stojković V; Lee DJ; Young ID; Szal T; Klepacki D; Vázquez-Laslop N; Mankin AS; Fraser JS; Fujimori DG
Nat Struct Mol Biol; 2022 Feb; 29(2):162-171. PubMed ID: 35165456
[TBL] [Abstract][Full Text] [Related]
4. Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action.
Xiong L; Kloss P; Douthwaite S; Andersen NM; Swaney S; Shinabarger DL; Mankin AS
J Bacteriol; 2000 Oct; 182(19):5325-31. PubMed ID: 10986233
[TBL] [Abstract][Full Text] [Related]
5. Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state.
Osterman IA; Khabibullina NF; Komarova ES; Kasatsky P; Kartsev VG; Bogdanov AA; Dontsova OA; Konevega AL; Sergiev PV; Polikanov YS
Nucleic Acids Res; 2017 Jul; 45(12):7507-7514. PubMed ID: 28505372
[TBL] [Abstract][Full Text] [Related]
6. Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes.
Aoki H; Ke L; Poppe SM; Poel TJ; Weaver EA; Gadwood RC; Thomas RC; Shinabarger DL; Ganoza MC
Antimicrob Agents Chemother; 2002 Apr; 46(4):1080-5. PubMed ID: 11897593
[TBL] [Abstract][Full Text] [Related]
7. Impact of P-Site tRNA and antibiotics on ribosome mediated protein folding: studies using the Escherichia coli ribosome.
Mondal S; Pathak BK; Ray S; Barat C
PLoS One; 2014; 9(7):e101293. PubMed ID: 25000563
[TBL] [Abstract][Full Text] [Related]
8. Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.
Porse BT; Kirillov SV; Awayez MJ; Ottenheijm HC; Garrett RA
Proc Natl Acad Sci U S A; 1999 Aug; 96(16):9003-8. PubMed ID: 10430885
[TBL] [Abstract][Full Text] [Related]
9. Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome.
Kirillov SV; Porse BT; Garrett RA
RNA; 1999 Aug; 5(8):1003-13. PubMed ID: 10445875
[TBL] [Abstract][Full Text] [Related]
10. Cross-linking in the living cell locates the site of action of oxazolidinone antibiotics.
Colca JR; McDonald WG; Waldon DJ; Thomasco LM; Gadwood RC; Lund ET; Cavey GS; Mathews WR; Adams LD; Cecil ET; Pearson JD; Bock JH; Mott JE; Shinabarger DL; Xiong L; Mankin AS
J Biol Chem; 2003 Jun; 278(24):21972-9. PubMed ID: 12690106
[TBL] [Abstract][Full Text] [Related]
11. Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center.
Kloss P; Xiong L; Shinabarger DL; Mankin AS
J Mol Biol; 1999 Nov; 294(1):93-101. PubMed ID: 10556031
[TBL] [Abstract][Full Text] [Related]
12. Peptidyl transferase and beyond.
Wower J; Wower IK; Kirillov SV; Rosen KV; Hixson SS; Zimmermann RA
Biochem Cell Biol; 1995; 73(11-12):1041-7. PubMed ID: 8722019
[TBL] [Abstract][Full Text] [Related]
13. The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria.
Leach KL; Swaney SM; Colca JR; McDonald WG; Blinn JR; Thomasco LM; Gadwood RC; Shinabarger D; Xiong L; Mankin AS
Mol Cell; 2007 May; 26(3):393-402. PubMed ID: 17499045
[TBL] [Abstract][Full Text] [Related]
14. R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance.
Skripkin E; McConnell TS; DeVito J; Lawrence L; Ippolito JA; Duffy EM; Sutcliffe J; Franceschi F
Antimicrob Agents Chemother; 2008 Oct; 52(10):3550-7. PubMed ID: 18663023
[TBL] [Abstract][Full Text] [Related]
15. Resistance to linezolid caused by modifications at its binding site on the ribosome.
Long KS; Vester B
Antimicrob Agents Chemother; 2012 Feb; 56(2):603-12. PubMed ID: 22143525
[TBL] [Abstract][Full Text] [Related]
16. The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance.
McCusker KP; Fujimori DG
ACS Chem Biol; 2012 Jan; 7(1):64-72. PubMed ID: 22208312
[TBL] [Abstract][Full Text] [Related]
17. Efficient ribosomal peptidyl transfer critically relies on the presence of the ribose 2'-OH at A2451 of 23S rRNA.
Erlacher MD; Lang K; Wotzel B; Rieder R; Micura R; Polacek N
J Am Chem Soc; 2006 Apr; 128(13):4453-9. PubMed ID: 16569023
[TBL] [Abstract][Full Text] [Related]
18. Antibiotic inhibition of the movement of tRNA substrates through a peptidyl transferase cavity.
Porse BT; Rodriguez-Fonseca C; Leviev I; Garrett RA
Biochem Cell Biol; 1995; 73(11-12):877-85. PubMed ID: 8722003
[TBL] [Abstract][Full Text] [Related]
19. The oxazolidinone class of drugs find their orientation on the ribosome.
Wilson DN; Nierhaus KH
Mol Cell; 2007 May; 26(4):460-2. PubMed ID: 17531804
[No Abstract] [Full Text] [Related]
20. Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit.
Ippolito JA; Kanyo ZF; Wang D; Franceschi FJ; Moore PB; Steitz TA; Duffy EM
J Med Chem; 2008 Jun; 51(12):3353-6. PubMed ID: 18494460
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
