BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 1875945)

  • 1. Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments.
    Fritz G; Tano K; Mitra S; Kaina B
    Mol Cell Biol; 1991 Sep; 11(9):4660-8. PubMed ID: 1875945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
    Dosch J; Kaina B
    Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes.
    Grombacher T; Mitra S; Kaina B
    Carcinogenesis; 1996 Nov; 17(11):2329-36. PubMed ID: 8968045
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genomic differences between O6-methylguanine-DNA methyltransferase proficient (Mex+) and deficient (Mex-) cell lines: possible role of genetic and epigenetic changes in conversion of Mex+ into Mex-.
    Fritz G; Kaina B
    Biochem Biophys Res Commun; 1992 Mar; 183(3):1184-90. PubMed ID: 1348932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents.
    Kaina B; Fritz G; Mitra S; Coquerelle T
    Carcinogenesis; 1991 Oct; 12(10):1857-67. PubMed ID: 1657427
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models.
    Kaina B; Ziouta A; Ochs K; Coquerelle T
    Mutat Res; 1997 Nov; 381(2):227-41. PubMed ID: 9434879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Constitutive expression and inducibility of O6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in rat liver cells exhibiting different status of differentiation.
    Grombacher T; Kaina B
    Biochim Biophys Acta; 1995 Jan; 1270(1):63-72. PubMed ID: 7827137
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting.
    Tominaga Y; Tsuzuki T; Shiraishi A; Kawate H; Sekiguchi M
    Carcinogenesis; 1997 May; 18(5):889-96. PubMed ID: 9163672
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stress factors affecting expression of O6-methylguanine-DNA methyltransferase mRNA in rat hepatoma cells.
    Fritz G; Kaina B
    Biochim Biophys Acta; 1992 Nov; 1171(1):35-40. PubMed ID: 1420362
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The origin of O6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells transfected with human DNA.
    Tano K; Shiota S; Remack JS; Brent TP; Bigner DD; Mitra S
    Mutat Res; 1991 Sep; 255(2):175-82. PubMed ID: 1922149
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bacterial O6-methylguanine-DNA methyltransferase reduces N-methyl-N'-nitro-N-nitrosoguanidine induction of plasminogen activator in Mer- human glioblastoma A1235 cell line.
    Loncarek J; Sorić J
    Mutat Res; 1998 Jul; 408(1):47-54. PubMed ID: 9678063
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of induction of O6-methylguanine-DNA methyltransferase in mammalian cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.
    Foote RS; Mitra S
    Carcinogenesis; 1984 Feb; 5(2):277-81. PubMed ID: 6697444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents.
    Wu ZN; Chan CL; Eastman A; Bresnick E
    Cancer Res; 1992 Jan; 52(1):32-5. PubMed ID: 1727384
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Strand- and sequence-specific attenuation of N-methyl-N'-nitro-N-nitrosoguanidine-induced G.C to A.T transitions by expression of human 6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells.
    Yang JL; Hsieh FP; Lee PC; Tseng HJ
    Cancer Res; 1994 Jul; 54(14):3857-63. PubMed ID: 8033107
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Relationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes.
    von Hofe E; Fairbairn L; Margison GP
    Proc Natl Acad Sci U S A; 1992 Dec; 89(23):11199-203. PubMed ID: 1454799
    [TBL] [Abstract][Full Text] [Related]  

  • 16. O6-methylguanine-DNA methyltransferase-defective human cell mutant: O6-methylguanine, DNA strand breaks and cytotoxicity.
    Kalamegham R; Warmels-Rodenhiser S; MacDonald H; Ebisuzaki K
    Carcinogenesis; 1988 Oct; 9(10):1749-53. PubMed ID: 3168154
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amplification of the DNA repair gene O6-methylguanine-DNA methyltransferase associated with resistance to alkylating drugs in a mammalian cell line.
    Tano K; Dunn WC; Darroudi F; Shiota S; Preston RJ; Natarajan AT; Mitra S
    J Biol Chem; 1997 May; 272(20):13250-4. PubMed ID: 9148943
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
    Dolan ME; Norbeck L; Clyde C; Hora NK; Erickson LC; Pegg AE
    Carcinogenesis; 1989 Sep; 10(9):1613-9. PubMed ID: 2766456
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Isolation of clones displaying enhanced resistance to methylating agents in O6-methylguanine-DNA methyltransferase-proficient CHO cells.
    Aquilina G; Frosina G; Zijno A; Di Muccio A; Dogliotti E; Abbondandolo A; Bignami M
    Carcinogenesis; 1988 Jul; 9(7):1217-22. PubMed ID: 3383340
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of human O6-methyl guanine methyl transferase (MGMT) in post replication repair (PRR) deficient CHO-UV-1 cells: compensation for hypersensitivity to methylating and ethylating agents but not to mitomycin C.
    Gustafson DL; Trotter BK; Snead D; Waldren CA
    Somat Cell Mol Genet; 1997 Jan; 23(1):9-17. PubMed ID: 9217997
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.