BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 18760267)

  • 1. Cytotoxicity and acid ceramidase inhibitory activity of 2-substituted aminoethanol amides.
    Bedia C; Canals D; Matabosch X; Harrak Y; Casas J; Llebaria A; Delgado A; Fabriás G
    Chem Phys Lipids; 2008 Nov; 156(1-2):33-40. PubMed ID: 18760267
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.
    Flowers M; Fabriás G; Delgado A; Casas J; Abad JL; Cabot MC
    Breast Cancer Res Treat; 2012 Jun; 133(2):447-58. PubMed ID: 21935601
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of acid ceramidase by a 2-substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N-(4-hydroxyphenyl) retinamide.
    Gouazé-Andersson V; Flowers M; Karimi R; Fabriás G; Delgado A; Casas J; Cabot MC
    Prostate; 2011 Jul; 71(10):1064-73. PubMed ID: 21557271
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3-Deoxy-3,4-dehydro analogs of XM462. Preparation and activity on sphingolipid metabolism and cell fate.
    Camacho L; Simbari F; Garrido M; Abad JL; Casas J; Delgado A; Fabriàs G
    Bioorg Med Chem; 2012 May; 20(10):3173-9. PubMed ID: 22537678
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet beta-cells.
    Zhu Q; Shan X; Miao H; Lu Y; Xu J; You N; Liu C; Liao DF; Jin J
    FEBS Lett; 2009 Jun; 583(12):2136-41. PubMed ID: 19497324
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effective inhibition of acid and neutral ceramidases by novel B-13 and LCL-464 analogues.
    Bhabak KP; Kleuser B; Huwiler A; Arenz C
    Bioorg Med Chem; 2013 Feb; 21(4):874-82. PubMed ID: 23312611
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel amide- and sulfonamide-based aromatic ethanolamines: effects of various substituents on the inhibition of acid and neutral ceramidases.
    Bhabak KP; Arenz C
    Bioorg Med Chem; 2012 Oct; 20(20):6162-70. PubMed ID: 22989912
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.
    Morad SA; Messner MC; Levin JC; Abdelmageed N; Park H; Merrill AH; Cabot MC
    Cancer Chemother Pharmacol; 2013 Mar; 71(3):635-45. PubMed ID: 23263160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells.
    Morad SA; Levin JC; Tan SF; Fox TE; Feith DJ; Cabot MC
    Biochim Biophys Acta; 2013 Dec; 1831(12):1657-64. PubMed ID: 23939396
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-Oleoylethanolamine inhibits glucosylation of natural ceramides in CHP-100 neuroepithelioma cells: possible implications for apoptosis.
    Spinedi A; Di Bartolomeo S; Piacentini M
    Biochem Biophys Res Commun; 1999 Feb; 255(2):456-9. PubMed ID: 10049730
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analogs of the dihydroceramide desaturase inhibitor GT11 modified at the amide function: synthesis and biological activities.
    Bedia C; Triola G; Casas J; Llebaria A; Fabriàs G
    Org Biomol Chem; 2005 Oct; 3(20):3707-12. PubMed ID: 16211106
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors.
    Han Y; Giroux A; Colucci J; Bayly CI; Mckay DJ; Roy S; Xanthoudakis S; Vaillancourt J; Rasper DM; Tam J; Tawa P; Nicholson DW; Zamboni RJ
    Bioorg Med Chem Lett; 2005 Feb; 15(4):1173-80. PubMed ID: 15686936
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR).
    Pizzirani D; Pagliuca C; Realini N; Branduardi D; Bottegoni G; Mor M; Bertozzi F; Scarpelli R; Piomelli D; Bandiera T
    J Med Chem; 2013 May; 56(9):3518-30. PubMed ID: 23614460
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of a novel ceramide analogue and its use in a high-throughput fluorogenic assay for ceramidases.
    Bedia C; Casas J; Garcia V; Levade T; Fabriàs G
    Chembiochem; 2007 Apr; 8(6):642-8. PubMed ID: 17361980
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues.
    Grijalvo S; Bedia C; Triola G; Casas J; Llebaria A; Teixidó J; Rabal O; Levade T; Delgado A; Fabriàs G
    Chem Phys Lipids; 2006 Oct; 144(1):69-84. PubMed ID: 16942762
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-Metallocenoylsphingosines as targeted ceramidase inhibitors: Syntheses and antitumoral effects.
    Rothemund M; Bär A; Klatt F; Weidler S; Köhler L; Unverzagt C; Kuhn CD; Schobert R
    Bioorg Chem; 2020 Apr; 97():103703. PubMed ID: 32143017
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and bioevaluation of omega-N-amino analogs of B13.
    Bai A; Szulc ZM; Bielawski J; Mayroo N; Liu X; Norris J; Hannun YA; Bielawska A
    Bioorg Med Chem; 2009 Mar; 17(5):1840-8. PubMed ID: 19217788
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Non-thiol farnesyltransferase inhibitors: N-(4-tolylacetylamino-3-benzoylphenyl)-3-arylfurylacrylic acid amides.
    Mitsch A; Wissner P; Silber K; Haebel P; Sattler I; Klebe G; Schlitzer M
    Bioorg Med Chem; 2004 Sep; 12(17):4585-600. PubMed ID: 15358286
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, structural characterization and biological evaluation of N-protected cyclopropylethylcarbamates as potential histone deacetylase inhibitor.
    Jung JC; Moon HI; Oh S
    Chem Biol Drug Des; 2008 Dec; 72(6):592-5. PubMed ID: 19090926
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors.
    Minkkilä A; Myllymäki MJ; Saario SM; Castillo-Melendez JA; Koskinen AM; Fowler CJ; Leppänen J; Nevalainen T
    Eur J Med Chem; 2009 Jul; 44(7):2994-3008. PubMed ID: 19232787
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.