139 related articles for article (PubMed ID: 18768392)
1. Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia.
Trentin L; Frasson M; Donella-Deana A; Frezzato F; Pagano MA; Tibaldi E; Gattazzo C; Zambello R; Semenzato G; Brunati AM
Blood; 2008 Dec; 112(12):4665-74. PubMed ID: 18768392
[TBL] [Abstract][Full Text] [Related]
2. Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells.
Tibaldi E; Brunati AM; Zonta F; Frezzato F; Gattazzo C; Zambello R; Gringeri E; Semenzato G; Pagano MA; Trentin L
Leukemia; 2011 Nov; 25(11):1768-81. PubMed ID: 21701493
[TBL] [Abstract][Full Text] [Related]
3. ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemia.
Castro JE; Prada CE; Loria O; Kamal A; Chen L; Burrows FJ; Kipps TJ
Blood; 2005 Oct; 106(7):2506-12. PubMed ID: 15972449
[TBL] [Abstract][Full Text] [Related]
4. Dasatinib inhibits B cell receptor signalling in chronic lymphocytic leukaemia but novel combination approaches are required to overcome additional pro-survival microenvironmental signals.
McCaig AM; Cosimo E; Leach MT; Michie AM
Br J Haematol; 2011 Apr; 153(2):199-211. PubMed ID: 21352196
[TBL] [Abstract][Full Text] [Related]
5. Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.
Contri A; Brunati AM; Trentin L; Cabrelle A; Miorin M; Cesaro L; Pinna LA; Zambello R; Semenzato G; Donella-Deana A
J Clin Invest; 2005 Feb; 115(2):369-78. PubMed ID: 15650771
[TBL] [Abstract][Full Text] [Related]
6. 17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition.
Hertlein E; Wagner AJ; Jones J; Lin TS; Maddocks KJ; Towns WH; Goettl VM; Zhang X; Jarjoura D; Raymond CA; West DA; Croce CM; Byrd JC; Johnson AJ
Blood; 2010 Jul; 116(1):45-53. PubMed ID: 20351313
[TBL] [Abstract][Full Text] [Related]
7. Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia.
Zonta F; Pagano MA; Trentin L; Tibaldi E; Frezzato F; Gattazzo C; Martini V; Trimarco V; Mazzorana M; Bordin L; Semenzato G; Brunati AM
Blood; 2014 Feb; 123(6):875-83. PubMed ID: 24352878
[TBL] [Abstract][Full Text] [Related]
8. Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A.
Zonta F; Pagano MA; Trentin L; Tibaldi E; Frezzato F; Trimarco V; Facco M; Zagotto G; Pavan V; Ribaudo G; Bordin L; Semenzato G; Brunati AM
Blood; 2015 Jun; 125(24):3747-55. PubMed ID: 25931585
[TBL] [Abstract][Full Text] [Related]
9. HSP90 stabilizes B-cell receptor kinases in a multi-client interactome: PU-H71 induces CLL apoptosis in a cytoprotective microenvironment.
Guo A; Lu P; Lee J; Zhen C; Chiosis G; Wang YL
Oncogene; 2017 Jun; 36(24):3441-3449. PubMed ID: 28114285
[TBL] [Abstract][Full Text] [Related]
10. Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia.
Chen TL; Gupta N; Lehman A; Ruppert AS; Yu L; Oakes CC; Claus R; Plass C; Maddocks KJ; Andritsos L; Jones JA; Lucas DM; Johnson AJ; Byrd JC; Hertlein E
Oncotarget; 2016 May; 7(19):28684-96. PubMed ID: 27107422
[TBL] [Abstract][Full Text] [Related]
11. HS1, a Lyn kinase substrate, is abnormally expressed in B-chronic lymphocytic leukemia and correlates with response to fludarabine-based regimen.
Frezzato F; Gattazzo C; Martini V; Trimarco V; Teramo A; Carraro S; Cabrelle A; Ave E; Facco M; Zambello R; Tibaldi E; Brunati AM; Semenzato G; Trentin L
PLoS One; 2012; 7(6):e39902. PubMed ID: 22768161
[TBL] [Abstract][Full Text] [Related]
12. Rituximab and 17-allylamino-17-demethoxygeldanamycin induce synergistic apoptosis in B-cell chronic lymphocytic leukaemia.
Johnson AJ; Wagner AJ; Cheney CM; Smith LL; Lucas DM; Guster SK; Grever MR; Lin TS; Byrd JC
Br J Haematol; 2007 Dec; 139(5):837-44. PubMed ID: 17949452
[TBL] [Abstract][Full Text] [Related]
13. Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs.
Jones DT; Addison E; North JM; Lowdell MW; Hoffbrand AV; Mehta AB; Ganeshaguru K; Folarin NI; Wickremasinghe RG
Blood; 2004 Mar; 103(5):1855-61. PubMed ID: 14576064
[TBL] [Abstract][Full Text] [Related]
14. Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells.
Lin K; Rockliffe N; Johnson GG; Sherrington PD; Pettitt AR
Oncogene; 2008 Apr; 27(17):2445-55. PubMed ID: 17982489
[TBL] [Abstract][Full Text] [Related]
15. Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia.
Ganguly S; Home T; Yacoub A; Kambhampati S; Shi H; Dandawate P; Padhye S; Saluja AK; McGuirk J; Rao R
Oncotarget; 2015 Oct; 6(31):31767-79. PubMed ID: 26397138
[TBL] [Abstract][Full Text] [Related]
16. Geldanamycin inhibits tyrosine phosphorylation-dependent NF-kappaB activation.
Crèvecoeur J; Merville MP; Piette J; Gloire G
Biochem Pharmacol; 2008 Jun; 75(11):2183-91. PubMed ID: 18455150
[TBL] [Abstract][Full Text] [Related]
17. The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells.
Higashi C; Saji C; Yamada K; Kagawa H; Ohga R; Taira T; Fujimuro M
Biol Pharm Bull; 2012; 35(5):725-30. PubMed ID: 22687408
[TBL] [Abstract][Full Text] [Related]
18. Targeting the LYN/HS1 signaling axis in chronic lymphocytic leukemia.
ten Hacken E; Scielzo C; Bertilaccio MT; Scarfò L; Apollonio B; Barbaglio F; Stamatopoulos K; Ponzoni M; Ghia P; Caligaris-Cappio F
Blood; 2013 Mar; 121(12):2264-73. PubMed ID: 23325840
[TBL] [Abstract][Full Text] [Related]
19. Rapid activation of c-Src kinase by dioxin is mediated by the Cdc37-HSP90 complex as part of Ah receptor signaling in MCF10A cells.
Park S; Dong B; Matsumura F
Biochemistry; 2007 Jan; 46(3):899-908. PubMed ID: 17223712
[TBL] [Abstract][Full Text] [Related]
20. Destabilization of ROR1 enhances activity of Ibrutinib against chronic lymphocytic leukemia in vivo.
Liu Z; Liu J; Zhang T; Shi M; Chen X; Chen Y; Yu J
Pharmacol Res; 2020 Jan; 151():104512. PubMed ID: 31726100
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
