BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

629 related articles for article (PubMed ID: 18769546)

  • 1. Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases.
    Tsigelny IF; Crews L; Desplats P; Shaked GM; Sharikov Y; Mizuno H; Spencer B; Rockenstein E; Trejo M; Platoshyn O; Yuan JX; Masliah E
    PLoS One; 2008 Sep; 3(9):e3135. PubMed ID: 18769546
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases.
    Hashimoto M; Rockenstein E; Crews L; Masliah E
    Neuromolecular Med; 2003; 4(1-2):21-36. PubMed ID: 14528050
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein.
    Tsigelny IF; Bar-On P; Sharikov Y; Crews L; Hashimoto M; Miller MA; Keller SH; Platoshyn O; Yuan JX; Masliah E
    FEBS J; 2007 Apr; 274(7):1862-77. PubMed ID: 17381514
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of synucleins in Alzheimer's disease.
    Crews L; Tsigelny I; Hashimoto M; Masliah E
    Neurotox Res; 2009 Oct; 16(3):306-17. PubMed ID: 19551456
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans.
    Huang X; Wang C; Chen L; Zhang T; Leung KL; Wong G
    Biochim Biophys Acta Mol Basis Dis; 2021 Oct; 1867(10):166203. PubMed ID: 34146705
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation.
    Tsigelny IF; Sharikov Y; Wrasidlo W; Gonzalez T; Desplats PA; Crews L; Spencer B; Masliah E
    FEBS J; 2012 Mar; 279(6):1000-13. PubMed ID: 22251432
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model.
    Spencer B; Desplats PA; Overk CR; Valera-Martin E; Rissman RA; Wu C; Mante M; Adame A; Florio J; Rockenstein E; Masliah E
    J Neurosci; 2016 Jul; 36(30):7971-84. PubMed ID: 27466341
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Non-Amyloid-β Component of Human α-Synuclein Oligomers Induces Formation of New Aβ Oligomers: Insight into the Mechanisms That Link Parkinson's and Alzheimer's Diseases.
    Atsmon-Raz Y; Miller Y
    ACS Chem Neurosci; 2016 Jan; 7(1):46-55. PubMed ID: 26479553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantifying regional α -synuclein, amyloid β, and tau accumulation in lewy body dementia.
    Miller RL; Dhavale DD; O'Shea JY; Andruska KM; Liu J; Franklin EE; Buddhala C; Loftin SK; Cirrito JR; Perrin RJ; Cairns NJ; Campbell MC; Perlmutter JS; Kotzbauer PT
    Ann Clin Transl Neurol; 2022 Feb; 9(2):106-121. PubMed ID: 35060360
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies.
    Overk CR; Cartier A; Shaked G; Rockenstein E; Ubhi K; Spencer B; Price DL; Patrick C; Desplats P; Masliah E
    Mol Neurodegener; 2014 May; 9():18. PubMed ID: 24885390
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson's disease: ex vivo and in vitro studies.
    Horvath I; Iashchishyn IA; Moskalenko RA; Wang C; Wärmländer SKTS; Wallin C; Gräslund A; Kovacs GG; Morozova-Roche LA
    J Neuroinflammation; 2018 Jun; 15(1):172. PubMed ID: 29866153
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions.
    Paleologou KE; Oueslati A; Shakked G; Rospigliosi CC; Kim HY; Lamberto GR; Fernandez CO; Schmid A; Chegini F; Gai WP; Chiappe D; Moniatte M; Schneider BL; Aebischer P; Eliezer D; Zweckstetter M; Masliah E; Lashuel HA
    J Neurosci; 2010 Mar; 30(9):3184-98. PubMed ID: 20203178
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.
    Vaikath NN; Majbour NK; Paleologou KE; Ardah MT; van Dam E; van de Berg WD; Forrest SL; Parkkinen L; Gai WP; Hattori N; Takanashi M; Lee SJ; Mann DM; Imai Y; Halliday GM; Li JY; El-Agnaf OM
    Neurobiol Dis; 2015 Jul; 79():81-99. PubMed ID: 25937088
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.
    Paleologou KE; Kragh CL; Mann DM; Salem SA; Al-Shami R; Allsop D; Hassan AH; Jensen PH; El-Agnaf OM
    Brain; 2009 Apr; 132(Pt 4):1093-101. PubMed ID: 19155272
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Associations Between APOE Variants, Tau and α-Synuclein.
    Rodriguez-Vieitez E; Nielsen HM
    Adv Exp Med Biol; 2019; 1184():177-186. PubMed ID: 32096038
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cerebral inoculation of human A53T α-synuclein reduces spatial memory decline and amyloid-β aggregation in APP/PS1 transgenic mice of Alzheimer's disease.
    Hao YN; Lu QX; Zhai YH; Wang HY; Wu MN; Hu MM; Yang B; Wang ZJ; Wu ZW; Qi JS
    Brain Res Bull; 2018 Oct; 143():116-122. PubMed ID: 30366065
    [TBL] [Abstract][Full Text] [Related]  

  • 17. α-Synuclein Heteromers in Red Blood Cells of Alzheimer's Disease and Lewy Body Dementia Patients.
    Daniele S; Baldacci F; Piccarducci R; Palermo G; Giampietri L; Manca ML; Pietrobono D; Frosini D; Nicoletti V; Tognoni G; Giorgi FS; Lo Gerfo A; Petrozzi L; Cavallini C; Franzoni F; Ceravolo R; Siciliano G; Trincavelli ML; Martini C; Bonuccelli U
    J Alzheimers Dis; 2021; 80(2):885-893. PubMed ID: 33579836
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction between Abeta peptide and alpha synuclein: molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease.
    Mandal PK; Pettegrew JW; Masliah E; Hamilton RL; Mandal R
    Neurochem Res; 2006 Sep; 31(9):1153-62. PubMed ID: 16947080
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity.
    Price DL; Rockenstein E; Ubhi K; Phung V; MacLean-Lewis N; Askay D; Cartier A; Spencer B; Patrick C; Desplats P; Ellisman MH; Masliah E
    PLoS One; 2010 Nov; 5(11):e14020. PubMed ID: 21103359
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alteration of Structure and Aggregation of α-Synuclein by Familial Parkinson's Disease Associated Mutations.
    Sahay S; Ghosh D; Singh PK; Maji SK
    Curr Protein Pept Sci; 2017; 18(7):656-676. PubMed ID: 26972727
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.