BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 18769708)

  • 1. Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways.
    Han S; Kim D
    PLoS Comput Biol; 2008 Aug; 4(8):e1000162. PubMed ID: 18769708
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method.
    Xie MW; Jin F; Hwang H; Hwang S; Anand V; Duncan MC; Huang J
    Proc Natl Acad Sci U S A; 2005 May; 102(20):7215-20. PubMed ID: 15883373
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemical-genetic approaches for exploring the mode of action of natural products.
    Lopez A; Parsons AB; Nislow C; Giaever G; Boone C
    Prog Drug Res; 2008; 66():237, 239-71. PubMed ID: 18416308
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.
    Parsons AB; Lopez A; Givoni IE; Williams DE; Gray CA; Porter J; Chua G; Sopko R; Brost RL; Ho CH; Wang J; Ketela T; Brenner C; Brill JA; Fernandez GE; Lorenz TC; Payne GS; Ishihara S; Ohya Y; Andrews B; Hughes TR; Frey BJ; Graham TR; Andersen RJ; Boone C
    Cell; 2006 Aug; 126(3):611-25. PubMed ID: 16901791
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways.
    Parsons AB; Brost RL; Ding H; Li Z; Zhang C; Sheikh B; Brown GW; Kane PM; Hughes TR; Boone C
    Nat Biotechnol; 2004 Jan; 22(1):62-9. PubMed ID: 14661025
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).
    Chan TF; Carvalho J; Riles L; Zheng XF
    Proc Natl Acad Sci U S A; 2000 Nov; 97(24):13227-32. PubMed ID: 11078525
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tor1 regulates protein solubility in Saccharomyces cerevisiae.
    Peters TW; Rardin MJ; Czerwieniec G; Evani US; Reis-Rodrigues P; Lithgow GJ; Mooney SD; Gibson BW; Hughes RE
    Mol Biol Cell; 2012 Dec; 23(24):4679-88. PubMed ID: 23097491
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evolutionary rate heterogeneity of core and attachment proteins in yeast protein complexes.
    Chakraborty S; Ghosh TC
    Genome Biol Evol; 2013; 5(7):1366-75. PubMed ID: 23814130
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A drug similarity network for understanding drug mechanism of action.
    Karabulut NP; Akhmedov M; Cokol M
    J Bioinform Comput Biol; 2014 Apr; 12(2):1441007. PubMed ID: 24712534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.
    Loewith R; Jacinto E; Wullschleger S; Lorberg A; Crespo JL; Bonenfant D; Oppliger W; Jenoe P; Hall MN
    Mol Cell; 2002 Sep; 10(3):457-68. PubMed ID: 12408816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2.
    Gaubitz C; Oliveira TM; Prouteau M; Leitner A; Karuppasamy M; Konstantinidou G; Rispal D; Eltschinger S; Robinson GC; Thore S; Aebersold R; Schaffitzel C; Loewith R
    Mol Cell; 2015 Jun; 58(6):977-88. PubMed ID: 26028537
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The synthetic genetic interaction network reveals small molecules that target specific pathways in Sacchromyces cerevisiae.
    Tamble CM; St Onge RP; Giaever G; Nislow C; Williams AG; Stuart JM; Lokey RS
    Mol Biosyst; 2011 Jun; 7(6):2019-30. PubMed ID: 21487606
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Detection of overlapping protein complexes in gene expression, phenotype and pathways of Saccharomyces cerevisiae using Prorank based Fuzzy algorithm.
    Manikandan P; Ramyachitra D; Banupriya D
    Gene; 2016 Apr; 580(2):144-158. PubMed ID: 26809099
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Screening for chemical inhibitors of heterologous proteins expressed in yeast using a simple growth-restoration assay.
    Balgi AD; Roberge M
    Methods Mol Biol; 2009; 486():125-37. PubMed ID: 19347620
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A common mechanism involving the TORC1 pathway can lead to amphotericin B-persistence in biofilm and planktonic Saccharomyces cerevisiae populations.
    Bojsen R; Regenberg B; Gresham D; Folkesson A
    Sci Rep; 2016 Feb; 6():21874. PubMed ID: 26903175
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.
    Collins SR; Miller KM; Maas NL; Roguev A; Fillingham J; Chu CS; Schuldiner M; Gebbia M; Recht J; Shales M; Ding H; Xu H; Han J; Ingvarsdottir K; Cheng B; Andrews B; Boone C; Berger SL; Hieter P; Zhang Z; Brown GW; Ingles CJ; Emili A; Allis CD; Toczyski DP; Weissman JS; Greenblatt JF; Krogan NJ
    Nature; 2007 Apr; 446(7137):806-10. PubMed ID: 17314980
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.
    Ericson E; Gebbia M; Heisler LE; Wildenhain J; Tyers M; Giaever G; Nislow C
    PLoS Genet; 2008 Aug; 4(8):e1000151. PubMed ID: 18688276
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Uncovering the rules for protein-protein interactions from yeast genomic data.
    Wang J; Li C; Wang E; Wang X
    Proc Natl Acad Sci U S A; 2009 Mar; 106(10):3752-7. PubMed ID: 19237561
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions.
    Qi Y; Suhail Y; Lin YY; Boeke JD; Bader JS
    Genome Res; 2008 Dec; 18(12):1991-2004. PubMed ID: 18832443
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae.
    Reinke A; Anderson S; McCaffery JM; Yates J; Aronova S; Chu S; Fairclough S; Iverson C; Wedaman KP; Powers T
    J Biol Chem; 2004 Apr; 279(15):14752-62. PubMed ID: 14736892
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.