These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 18771289)

  • 1. Intrinsic ssDNA annealing activity in the C-terminal region of WRN.
    Muftuoglu M; Kulikowicz T; Beck G; Lee JW; Piotrowski J; Bohr VA
    Biochemistry; 2008 Sep; 47(39):10247-54. PubMed ID: 18771289
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional deficit associated with a missense Werner syndrome mutation.
    Tadokoro T; Rybanska-Spaeder I; Kulikowicz T; Dawut L; Oshima J; Croteau DL; Bohr VA
    DNA Repair (Amst); 2013 Jun; 12(6):414-21. PubMed ID: 23583337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA binding residues in the RQC domain of Werner protein are critical for its catalytic activities.
    Tadokoro T; Kulikowicz T; Dawut L; Croteau DL; Bohr VA
    Aging (Albany NY); 2012 Jun; 4(6):417-29. PubMed ID: 22713343
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of the HRDC domain of human Werner syndrome protein, WRN.
    Kitano K; Yoshihara N; Hakoshima T
    J Biol Chem; 2007 Jan; 282(4):2717-28. PubMed ID: 17148451
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Replication protein A stimulates the Werner syndrome protein branch migration activity.
    Sowd G; Wang H; Pretto D; Chazin WJ; Opresko PL
    J Biol Chem; 2009 Dec; 284(50):34682-91. PubMed ID: 19812417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multimerization domains are associated with apparent strand exchange activity in BLM and WRN DNA helicases.
    Chen CF; Brill SJ
    DNA Repair (Amst); 2014 Oct; 22():137-46. PubMed ID: 25198671
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA secondary structure of the released strand stimulates WRN helicase action on forked duplexes without coordinate action of WRN exonuclease.
    Ahn B; Bohr VA
    Biochem Biophys Res Commun; 2011 Aug; 411(4):684-9. PubMed ID: 21763283
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activity.
    Li B; Reddy S; Comai L
    Aging (Albany NY); 2009 Mar; 1(3):289-302. PubMed ID: 20157518
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
    Machwe A; Lozada EM; Xiao L; Orren DK
    BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions.
    Popp O; Veith S; Fahrer J; Bohr VA; Bürkle A; Mangerich A
    ACS Chem Biol; 2013 Jan; 8(1):179-88. PubMed ID: 23082994
    [TBL] [Abstract][Full Text] [Related]  

  • 11. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
    Aggarwal M; Brosh RM
    Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domains.
    Machwe A; Xiao L; Orren DK
    BMC Mol Biol; 2006 Feb; 7():6. PubMed ID: 16503984
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity.
    Perry JJ; Asaithamby A; Barnebey A; Kiamanesch F; Chen DJ; Han S; Tainer JA; Yannone SM
    J Biol Chem; 2010 Aug; 285(33):25699-707. PubMed ID: 20516064
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase.
    Sowd G; Lei M; Opresko PL
    Nucleic Acids Res; 2008 Aug; 36(13):4242-56. PubMed ID: 18583366
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain.
    Lee JW; Kusumoto R; Doherty KM; Lin GX; Zeng W; Cheng WH; von Kobbe C; Brosh RM; Hu JS; Bohr VA
    J Biol Chem; 2005 Nov; 280(47):39627-36. PubMed ID: 16150736
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enzymatic mechanism of the WRN helicase/nuclease.
    Brosh RM; Opresko PL; Bohr VA
    Methods Enzymol; 2006; 409():52-85. PubMed ID: 16793395
    [TBL] [Abstract][Full Text] [Related]  

  • 17. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
    Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
    Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DmWRNexo is a 3'-5' exonuclease: phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease.
    Boubriak I; Mason PA; Clancy DJ; Dockray J; Saunders RD; Cox LS
    Biogerontology; 2009 Jun; 10(3):267-77. PubMed ID: 18956248
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells.
    Futami K; Ishikawa Y; Goto M; Furuichi Y; Sugimoto M
    Cancer Sci; 2008 May; 99(5):843-8. PubMed ID: 18312465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.
    Shen JC; Gray MD; Oshima J; Kamath-Loeb AS; Fry M; Loeb LA
    J Biol Chem; 1998 Dec; 273(51):34139-44. PubMed ID: 9852073
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.