These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 18771817)

  • 1. Intracellular Aß triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease.
    Christensen DZ; Bayer TA; Wirths O
    Neurobiol Aging; 2010 Jul; 31(7):1153-63. PubMed ID: 18771817
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transient intraneuronal A beta rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice.
    Christensen DZ; Kraus SL; Flohr A; Cotel MC; Wirths O; Bayer TA
    Acta Neuropathol; 2008 Dec; 116(6):647-55. PubMed ID: 18974993
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.
    Salehi A; Delcroix JD; Belichenko PV; Zhan K; Wu C; Valletta JS; Takimoto-Kimura R; Kleschevnikov AM; Sambamurti K; Chung PP; Xia W; Villar A; Campbell WA; Kulnane LS; Nixon RA; Lamb BT; Epstein CJ; Stokin GB; Goldstein LS; Mobley WC
    Neuron; 2006 Jul; 51(1):29-42. PubMed ID: 16815330
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Review on the APP/PS1KI mouse model: intraneuronal Abeta accumulation triggers axonopathy, neuron loss and working memory impairment.
    Bayer TA; Wirths O
    Genes Brain Behav; 2008 Feb; 7 Suppl 1():6-11. PubMed ID: 18184366
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease.
    Wirths O; Breyhan H; Marcello A; Cotel MC; Brück W; Bayer TA
    Neurobiol Aging; 2010 May; 31(5):747-57. PubMed ID: 18657882
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer's disease.
    Moon M; Hong HS; Nam DW; Baik SH; Song H; Kook SY; Kim YS; Lee J; Mook-Jung I
    J Alzheimers Dis; 2012; 29(3):615-28. PubMed ID: 22269161
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intraneuronal beta-amyloid is a major risk factor--novel evidence from the APP/PS1KI mouse model.
    Bayer TA; Breyhan H; Duan K; Rettig J; Wirths O
    Neurodegener Dis; 2008; 5(3-4):140-2. PubMed ID: 18322372
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease.
    Jawhar S; Trawicka A; Jenneckens C; Bayer TA; Wirths O
    Neurobiol Aging; 2012 Jan; 33(1):196.e29-40. PubMed ID: 20619937
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The presence of the APP(swe) mutation in mice does not increase the vulnerability of cholinergic basal forebrain neurons to neuroinflammation.
    Wenk GL; McGann-Gramling K; Hauss-Wegrzyniak B
    Neuroscience; 2004; 125(3):769-76. PubMed ID: 15099690
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APP/PS1KI bigenic mice develop early synaptic deficits and hippocampus atrophy.
    Breyhan H; Wirths O; Duan K; Marcello A; Rettig J; Bayer TA
    Acta Neuropathol; 2009 Jun; 117(6):677-85. PubMed ID: 19387667
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective cholinergic denervation, independent from oxidative stress, in a mouse model of Alzheimer's disease.
    Aucoin JS; Jiang P; Aznavour N; Tong XK; Buttini M; Descarries L; Hamel E
    Neuroscience; 2005; 132(1):73-86. PubMed ID: 15780468
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cholinergic neuropathology in a mouse model of Alzheimer's disease.
    German DC; Yazdani U; Speciale SG; Pasbakhsh P; Games D; Liang CL
    J Comp Neurol; 2003 Aug; 462(4):371-81. PubMed ID: 12811807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S; Counts SE; Ma SY; Dadko E; Gordon MN; Morgan D; Mufson EJ
    Exp Neurol; 2001 Aug; 170(2):227-43. PubMed ID: 11476589
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intraneuronal amyloid beta and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease.
    Van Broeck B; Vanhoutte G; Pirici D; Van Dam D; Wils H; Cuijt I; Vennekens K; Zabielski M; Michalik A; Theuns J; De Deyn PP; Van der Linden A; Van Broeckhoven C; Kumar-Singh S
    Neurobiol Aging; 2008 Feb; 29(2):241-52. PubMed ID: 17112635
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cholinergic system in aging and neuronal degeneration.
    Schliebs R; Arendt T
    Behav Brain Res; 2011 Aug; 221(2):555-63. PubMed ID: 21145918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease.
    Schmitz C; Rutten BP; Pielen A; Schäfer S; Wirths O; Tremp G; Czech C; Blanchard V; Multhaup G; Rezaie P; Korr H; Steinbusch HW; Pradier L; Bayer TA
    Am J Pathol; 2004 Apr; 164(4):1495-502. PubMed ID: 15039236
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on Aβ accumulation and cell death: involvement in hippocampal neuronal loss in Alzheimer's disease.
    Antequera D; Bolos M; Spuch C; Pascual C; Ferrer I; Fernandez-Bachiller MI; Rodríguez-Franco MI; Carro E
    Neurobiol Dis; 2012 Jun; 46(3):682-91. PubMed ID: 22426395
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene Expression Profiling in the APP/PS1KI Mouse Model of Familial Alzheimer's Disease.
    Weissmann R; Hüttenrauch M; Kacprowski T; Bouter Y; Pradier L; Bayer TA; Kuss AW; Wirths O
    J Alzheimers Dis; 2016; 50(2):397-409. PubMed ID: 26639971
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine.
    Nyakas C; Granic I; Halmy LG; Banerjee P; Luiten PG
    Behav Brain Res; 2011 Aug; 221(2):594-603. PubMed ID: 20553766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Melatonin alleviates behavioral deficits associated with apoptosis and cholinergic system dysfunction in the APP 695 transgenic mouse model of Alzheimer's disease.
    Feng Z; Chang Y; Cheng Y; Zhang BL; Qu ZW; Qin C; Zhang JT
    J Pineal Res; 2004 Sep; 37(2):129-36. PubMed ID: 15298672
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.