220 related articles for article (PubMed ID: 18772127)
1. Regulation of receptor signaling by relaxin A chain motifs: derivation of pan-specific and LGR7-specific human relaxin analogs.
Park JI; Semyonov J; Yi W; Chang CL; Hsu SY
J Biol Chem; 2008 Nov; 283(46):32099-109. PubMed ID: 18772127
[TBL] [Abstract][Full Text] [Related]
2. Defining the LGR8 residues involved in binding insulin-like peptide 3.
Scott DJ; Wilkinson TN; Zhang S; Ferraro T; Wade JD; Tregear GW; Bathgate RA
Mol Endocrinol; 2007 Jul; 21(7):1699-712. PubMed ID: 17473281
[TBL] [Abstract][Full Text] [Related]
3. Genetic targeting of relaxin and insl3 signaling in mice.
Feng S; Bogatcheva NV; Kamat AA; Agoulnik AI
Ann N Y Acad Sci; 2005 May; 1041():82-90. PubMed ID: 15956690
[TBL] [Abstract][Full Text] [Related]
4. Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.
Bathgate RA; Lin F; Hanson NF; Otvos L; Guidolin A; Giannakis C; Bastiras S; Layfield SL; Ferraro T; Ma S; Zhao C; Gundlach AL; Samuel CS; Tregear GW; Wade JD
Biochemistry; 2006 Jan; 45(3):1043-53. PubMed ID: 16411781
[TBL] [Abstract][Full Text] [Related]
5. The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors.
Hossain MA; Rosengren KJ; Haugaard-Jönsson LM; Zhang S; Layfield S; Ferraro T; Daly NL; Tregear GW; Wade JD; Bathgate RA
J Biol Chem; 2008 Jun; 283(25):17287-97. PubMed ID: 18434306
[TBL] [Abstract][Full Text] [Related]
6. H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.
Sudo S; Kumagai J; Nishi S; Layfield S; Ferraro T; Bathgate RA; Hsueh AJ
J Biol Chem; 2003 Mar; 278(10):7855-62. PubMed ID: 12506116
[TBL] [Abstract][Full Text] [Related]
7. The NMR solution structure of the relaxin (RXFP1) receptor lipoprotein receptor class A module and identification of key residues in the N-terminal region of the module that mediate receptor activation.
Hopkins EJ; Layfield S; Ferraro T; Bathgate RA; Gooley PR
J Biol Chem; 2007 Feb; 282(6):4172-84. PubMed ID: 17148455
[TBL] [Abstract][Full Text] [Related]
8. Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8).
Halls ML; Bond CP; Sudo S; Kumagai J; Ferraro T; Layfield S; Bathgate RA; Summers RJ
J Pharmacol Exp Ther; 2005 May; 313(2):677-87. PubMed ID: 15649866
[TBL] [Abstract][Full Text] [Related]
9. Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity.
Muda M; He C; Martini PG; Ferraro T; Layfield S; Taylor D; Chevrier C; Schweickhardt R; Kelton C; Ryan PL; Bathgate RA
Mol Hum Reprod; 2005 Aug; 11(8):591-600. PubMed ID: 16051677
[TBL] [Abstract][Full Text] [Related]
10. Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3.
Rosengren KJ; Lin F; Bathgate RA; Tregear GW; Daly NL; Wade JD; Craik DJ
J Biol Chem; 2006 Mar; 281(9):5845-51. PubMed ID: 16365033
[TBL] [Abstract][Full Text] [Related]
11. Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.
Scott DJ; Layfield S; Yan Y; Sudo S; Hsueh AJ; Tregear GW; Bathgate RA
J Biol Chem; 2006 Nov; 281(46):34942-54. PubMed ID: 16963451
[TBL] [Abstract][Full Text] [Related]
12. The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane.
Kern A; Agoulnik AI; Bryant-Greenwood GD
Endocrinology; 2007 Mar; 148(3):1181-94. PubMed ID: 17158203
[TBL] [Abstract][Full Text] [Related]
13. The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1.
Sethi A; Bruell S; Patil N; Hossain MA; Scott DJ; Petrie EJ; Bathgate RAD; Gooley PR
Nat Commun; 2016 Apr; 7():11344. PubMed ID: 27088579
[TBL] [Abstract][Full Text] [Related]
14. Relaxin enhances the oncogenic potential of human thyroid carcinoma cells.
Hombach-Klonisch S; Bialek J; Trojanowicz B; Weber E; Holzhausen HJ; Silvertown JD; Summerlee AJ; Dralle H; Hoang-Vu C; Klonisch T
Am J Pathol; 2006 Aug; 169(2):617-32. PubMed ID: 16877360
[TBL] [Abstract][Full Text] [Related]
15. Relaxin research in the postgenomic era.
Kawamura K; Sudo S; Kumagai J; Pisarska M; Hsu SY; Bathgate R; Wade J; Hsueh AJ
Ann N Y Acad Sci; 2005 May; 1041():1-7. PubMed ID: 15956679
[TBL] [Abstract][Full Text] [Related]
16. Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.
Liu C; Chen J; Kuei C; Sutton S; Nepomuceno D; Bonaventure P; Lovenberg TW
Mol Pharmacol; 2005 Jan; 67(1):231-40. PubMed ID: 15465925
[TBL] [Abstract][Full Text] [Related]
17. The electrostatic interactions of relaxin-3 with receptor RXFP4 and the influence of its B-chain C-terminal conformation.
Wang XY; Guo YQ; Zhang WJ; Shao XX; Liu YL; Xu ZG; Guo ZY
FEBS J; 2014 Jul; 281(13):2927-36. PubMed ID: 24802387
[TBL] [Abstract][Full Text] [Related]
18. Studies on soluble ectodomain proteins of relaxin (LGR7) and insulin 3 (LGR8) receptors.
Yan Y; Cai J; Fu P; Layfield S; Ferraro T; Kumagai J; Sudo S; Tang JG; Giannakis E; Tregear GW; Wade JD; Bathgate RA
Ann N Y Acad Sci; 2005 May; 1041():35-9. PubMed ID: 15956685
[TBL] [Abstract][Full Text] [Related]
19. Probing the functional domains of relaxin-3 and the creation of a selective antagonist for RXFP3/GPCR135 over relaxin receptor RXFP1/LGR7.
Liu C; Kuei C; Sutton S; Shelton J; Zhu J; Nepomuceno D; Hossain MA; Wade JD; Bathgate RA; Bonaventure P; Lovenberg T
Ann N Y Acad Sci; 2009 Apr; 1160():31-7. PubMed ID: 19416155
[TBL] [Abstract][Full Text] [Related]
20. Identification of binding sites with differing affinity and potency for relaxin analogues on LGR7 and LGR8 receptors.
Halls ML; Bathgate RA; Sudo S; Kumagai J; Bond CP; Summers RJ
Ann N Y Acad Sci; 2005 May; 1041():17-21. PubMed ID: 15956682
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]