BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 18772390)

  • 1. Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis.
    Kurschus FC; Fellows E; Stegmann E; Jenne DE
    Proc Natl Acad Sci U S A; 2008 Sep; 105(37):13799-804. PubMed ID: 18772390
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Delivery and therapeutic potential of human granzyme B.
    Kurschus FC; Jenne DE
    Immunol Rev; 2010 May; 235(1):159-71. PubMed ID: 20536562
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis.
    Shi L; Keefe D; Durand E; Feng H; Zhang D; Lieberman J
    J Immunol; 2005 May; 174(9):5456-61. PubMed ID: 15843543
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Membrane receptors are not required to deliver granzyme B during killer cell attack.
    Kurschus FC; Bruno R; Fellows E; Falk CS; Jenne DE
    Blood; 2005 Mar; 105(5):2049-58. PubMed ID: 15528317
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis.
    Thiery J; Keefe D; Saffarian S; Martinvalet D; Walch M; Boucrot E; Kirchhausen T; Lieberman J
    Blood; 2010 Feb; 115(8):1582-93. PubMed ID: 20038786
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate.
    Veugelers K; Motyka B; Goping IS; Shostak I; Sawchuk T; Bleackley RC
    Mol Biol Cell; 2006 Feb; 17(2):623-33. PubMed ID: 16280358
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells.
    Thiery J; Keefe D; Boulant S; Boucrot E; Walch M; Martinvalet D; Goping IS; Bleackley RC; Kirchhausen T; Lieberman J
    Nat Immunol; 2011 Jun; 12(8):770-7. PubMed ID: 21685908
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Perforin is recaptured by natural killer cells following target cells stimulation for cytotoxicity.
    Wang L; Sun R; Li P; Han Y; Xiong P; Xu Y; Fang M; Tan Z; Zheng F; Gong F
    Cell Biol Int; 2012 Feb; 36(2):223-8. PubMed ID: 21981014
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes.
    Metkar SS; Marchioretto M; Antonini V; Lunelli L; Wang B; Gilbert RJ; Anderluh G; Roth R; Pooga M; Pardo J; Heuser JE; Serra MD; Froelich CJ
    Cell Death Differ; 2015 Jan; 22(1):74-85. PubMed ID: 25146929
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Killing of target cells by redirected granzyme B in the absence of perforin.
    Kurschus FC; Kleinschmidt M; Fellows E; Dornmair K; Rudolph R; Lilie H; Jenne DE
    FEBS Lett; 2004 Mar; 562(1-3):87-92. PubMed ID: 15044006
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.
    Trapani JA; Sutton VR; Thia KY; Li YQ; Froelich CJ; Jans DA; Sandrin MS; Browne KA
    J Cell Biol; 2003 Jan; 160(2):223-33. PubMed ID: 12538642
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reassessing granzyme B: unveiling perforin-independent versatility in immune responses and therapeutic potentials.
    Thompson R; Cao X
    Front Immunol; 2024; 15():1392535. PubMed ID: 38846935
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential cleavage of viral polypeptides by allotypic variants of granzyme B skews immunity to mouse cytomegalovirus.
    Sutton VR; Andoniou C; Leeming MG; House CM; Watt SV; Verschoor S; Ciccone A; Voskoboinik I; Degli-Esposti M; Trapani JA
    Biochim Biophys Acta Proteins Proteom; 2020 Sep; 1868(9):140457. PubMed ID: 32473350
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Orphan granzymes find a home.
    Bovenschen N; Kummer JA
    Immunol Rev; 2010 May; 235(1):117-27. PubMed ID: 20536559
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Perforin rapidly induces plasma membrane phospholipid flip-flop.
    Metkar SS; Wang B; Catalan E; Anderluh G; Gilbert RJ; Pardo J; Froelich CJ
    PLoS One; 2011; 6(9):e24286. PubMed ID: 21931672
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
    Metkar SS; Wang B; Aguilar-Santelises M; Raja SM; Uhlin-Hansen L; Podack E; Trapani JA; Froelich CJ
    Immunity; 2002 Mar; 16(3):417-28. PubMed ID: 11911826
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.
    Pardo J; Wallich R; Ebnet K; Iden S; Zentgraf H; Martin P; Ekiciler A; Prins A; Müllbacher A; Huber M; Simon MM
    Cell Death Differ; 2007 Oct; 14(10):1768-79. PubMed ID: 17599099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Perforin activity at membranes leads to invaginations and vesicle formation.
    Praper T; Sonnen AF; Kladnik A; Andrighetti AO; Viero G; Morris KJ; Volpi E; Lunelli L; Dalla Serra M; Froelich CJ; Gilbert RJ; Anderluh G
    Proc Natl Acad Sci U S A; 2011 Dec; 108(52):21016-21. PubMed ID: 22173634
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The perforin pore facilitates the delivery of cationic cargos.
    Stewart SE; Kondos SC; Matthews AY; D'Angelo ME; Dunstone MA; Whisstock JC; Trapani JA; Bird PI
    J Biol Chem; 2014 Mar; 289(13):9172-81. PubMed ID: 24558045
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Novel Serpin Regulatory Mechanism: SerpinB9 IS REVERSIBLY INHIBITED BY VICINAL DISULFIDE BOND FORMATION IN THE REACTIVE CENTER LOOP.
    Mangan MS; Bird CH; Kaiserman D; Matthews AY; Hitchen C; Steer DL; Thompson PE; Bird PI
    J Biol Chem; 2016 Feb; 291(7):3626-38. PubMed ID: 26670609
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.