BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

423 related articles for article (PubMed ID: 18772888)

  • 1. The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix.
    Hashimoto H; Horton JR; Zhang X; Bostick M; Jacobsen SE; Cheng X
    Nature; 2008 Oct; 455(7214):826-9. PubMed ID: 18772888
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism.
    Arita K; Ariyoshi M; Tochio H; Nakamura Y; Shirakawa M
    Nature; 2008 Oct; 455(7214):818-21. PubMed ID: 18772891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
    Avvakumov GV; Walker JR; Xue S; Li Y; Duan S; Bronner C; Arrowsmith CH; Dhe-Paganon S
    Nature; 2008 Oct; 455(7214):822-5. PubMed ID: 18772889
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.
    Bashtrykov P; Jankevicius G; Jurkowska RZ; Ragozin S; Jeltsch A
    J Biol Chem; 2014 Feb; 289(7):4106-15. PubMed ID: 24368767
    [TBL] [Abstract][Full Text] [Related]  

  • 5. UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
    Hashimoto H; Horton JR; Zhang X; Cheng X
    Epigenetics; 2009 Jan; 4(1):8-14. PubMed ID: 19077538
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure and hemimethylated CpG binding of the SRA domain from human UHRF1.
    Qian C; Li S; Jakoncic J; Zeng L; Walsh MJ; Zhou MM
    J Biol Chem; 2008 Dec; 283(50):34490-4. PubMed ID: 18945682
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9.
    Liu X; Gao Q; Li P; Zhao Q; Zhang J; Li J; Koseki H; Wong J
    Nat Commun; 2013; 4():1563. PubMed ID: 23463006
    [TBL] [Abstract][Full Text] [Related]  

  • 8. UHRF1 plays a role in maintaining DNA methylation in mammalian cells.
    Bostick M; Kim JK; Estève PO; Clark A; Pradhan S; Jacobsen SE
    Science; 2007 Sep; 317(5845):1760-4. PubMed ID: 17673620
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.
    Frauer C; Hoffmann T; Bultmann S; Casa V; Cardoso MC; Antes I; Leonhardt H
    PLoS One; 2011; 6(6):e21306. PubMed ID: 21731699
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation.
    Vaughan RM; Rothbart SB; Dickson BM
    J Biol Chem; 2019 Oct; 294(43):15724-15732. PubMed ID: 31481468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The DNA methyltransferase Dnmt1 directly interacts with the SET and RING finger-associated (SRA) domain of the multifunctional protein Uhrf1 to facilitate accession of the catalytic center to hemi-methylated DNA.
    Berkyurek AC; Suetake I; Arita K; Takeshita K; Nakagawa A; Shirakawa M; Tajima S
    J Biol Chem; 2014 Jan; 289(1):379-86. PubMed ID: 24253042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based screening of chemical libraries to identify small molecules that are likely to bind with the SET and RING-associated (SRA) domain of Ubiquitin-like, PHD and Ring Finger-containing 1 (UHRF1).
    Patnaik D
    BMC Res Notes; 2020 May; 13(1):254. PubMed ID: 32448288
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dynamics of Methylated Cytosine Flipping by UHRF1.
    Kilin V; Gavvala K; Barthes NP; Michel BY; Shin D; Boudier C; Mauffret O; Yashchuk V; Mousli M; Ruff M; Granger F; Eiler S; Bronner C; Tor Y; Burger A; Mély Y
    J Am Chem Soc; 2017 Feb; 139(6):2520-2528. PubMed ID: 28112929
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA.
    Abhishek S; Nakarakanti NK; Deeksha W; Rajakumara E
    Int J Biol Macromol; 2021 Feb; 170():514-522. PubMed ID: 33359809
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Systematic analysis of the binding behaviour of UHRF1 towards different methyl- and carboxylcytosine modification patterns at CpG dyads.
    Schneider M; Trummer C; Stengl A; Zhang P; Szwagierczak A; Cardoso MC; Leonhardt H; Bauer C; Antes I
    PLoS One; 2020; 15(2):e0229144. PubMed ID: 32084194
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation.
    Song J; Teplova M; Ishibe-Murakami S; Patel DJ
    Science; 2012 Feb; 335(6069):709-12. PubMed ID: 22323818
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Molecular Tool Targeting the Base-Flipping Activity of Human UHRF1.
    Zaayter L; Mori M; Ahmad T; Ashraf W; Boudier C; Kilin V; Gavvala K; Richert L; Eiler S; Ruff M; Botta M; Bronner C; Mousli M; Mély Y
    Chemistry; 2019 Oct; 25(58):13363-13375. PubMed ID: 31322780
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Site-Selective Monitoring of the Interaction of the SRA Domain of UHRF1 with Target DNA Sequences Labeled with 2-Aminopurine.
    Greiner VJ; Kovalenko L; Humbert N; Richert L; Birck C; Ruff M; Zaporozhets OA; Dhe-Paganon S; Bronner C; Mély Y
    Biochemistry; 2015 Oct; 54(39):6012-20. PubMed ID: 26368281
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-germ Line Restoration of Genomic Imprinting for a Small Subset of Imprinted Genes in Ubiquitin-like PHD and RING Finger Domain-Containing 1 (Uhrf1) Null Mouse Embryonic Stem Cells.
    Qi S; Wang Z; Li P; Wu Q; Shi T; Li J; Wong J
    J Biol Chem; 2015 May; 290(22):14181-91. PubMed ID: 25900245
    [TBL] [Abstract][Full Text] [Related]  

  • 20. UHRF1 discriminates against binding to fully-methylated CpG-Sites by steric repulsion.
    Bianchi C; Zangi R
    Biophys Chem; 2013 Jan; 171():38-45. PubMed ID: 23245651
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.