BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 18773943)

  • 1. Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury.
    Wen XR; Li C; Zong YY; Yu CZ; Xu J; Han D; Zhang GY
    Neuroscience; 2008 Oct; 156(3):483-97. PubMed ID: 18773943
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neuroprotection of selenite against ischemic brain injury through negatively regulating early activation of ASK1/JNK cascade via activation of PI3K/AKT pathway.
    Wang Q; Zhang QG; Wu DN; Yin XH; Zhang GY
    Acta Pharmacol Sin; 2007 Jan; 28(1):19-27. PubMed ID: 17184578
    [TBL] [Abstract][Full Text] [Related]  

  • 3. K252a prevents nigral dopaminergic cell death induced by 6-hydroxydopamine through inhibition of both mixed-lineage kinase 3/c-Jun NH2-terminal kinase 3 (JNK3) and apoptosis-inducing kinase 1/JNK3 signaling pathways.
    Pan J; Wang G; Yang HQ; Hong Z; Xiao Q; Ren RJ; Zhou HY; Bai L; Chen SD
    Mol Pharmacol; 2007 Dec; 72(6):1607-18. PubMed ID: 17855652
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region.
    Pan J; Zhang QG; Zhang GY
    Neuroscience; 2005; 131(1):147-59. PubMed ID: 15680699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neuroprotection of Sevoflurane Against Ischemia/Reperfusion-Induced Brain Injury Through Inhibiting JNK3/Caspase-3 by Enhancing Akt Signaling Pathway.
    Wen XR; Fu YY; Liu HZ; Wu J; Shao XP; Zhang XB; Tang M; Shi Y; Ma K; Zhang F; Wang YW; Tang H; Han D; Zhang P; Wang SL; Xu Z; Song YJ
    Mol Neurobiol; 2016 Apr; 53(3):1661-1671. PubMed ID: 25687432
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of c-Jun NH2-terminal kinase 3 is mediated by the GluR6.PSD-95.MLK3 signaling module following cerebral ischemia in rat hippocampus.
    Tian H; Zhang QG; Zhu GX; Pei DS; Guan QH; Zhang GY
    Brain Res; 2005 Nov; 1061(1):57-66. PubMed ID: 16256962
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Additive neuroprotection of GABA A and GABA B receptor agonists in cerebral ischemic injury via PI-3K/Akt pathway inhibiting the ASK1-JNK cascade.
    Xu J; Li C; Yin XH; Zhang GY
    Neuropharmacology; 2008 Jun; 54(7):1029-40. PubMed ID: 18410948
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of MLK3-MKK4/7-JNK1/2 pathway by Akt1 in exogenous estrogen-induced neuroprotection against transient global cerebral ischemia by a non-genomic mechanism in male rats.
    Wang R; Zhang QG; Han D; Xu J; Lü Q; Zhang GY
    J Neurochem; 2006 Dec; 99(6):1543-54. PubMed ID: 17064355
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antioxidant N-acetylcysteine inhibits the activation of JNK3 mediated by the GluR6-PSD95-MLK3 signaling module during cerebral ischemia in rat hippocampus.
    Zhang QG; Tian H; Li HC; Zhang GY
    Neurosci Lett; 2006 Nov; 408(3):159-64. PubMed ID: 17030433
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ischemic preconditioning negatively regulates plenty of SH3s-mixed lineage kinase 3-Rac1 complex and c-Jun N-terminal kinase 3 signaling via activation of Akt.
    Zhang QG; Han D; Xu J; Lv Q; Wang R; Yin XH; Xu TL; Zhang GY
    Neuroscience; 2006 Dec; 143(2):431-44. PubMed ID: 16973299
    [TBL] [Abstract][Full Text] [Related]  

  • 11. H₂S attenuates cognitive deficits through Akt1/JNK3 signaling pathway in ischemic stroke.
    Wen X; Qi D; Sun Y; Huang X; Zhang F; Wu J; Fu Y; Ma K; Du Y; Dong H; Liu Y; Liu H; Song Y
    Behav Brain Res; 2014 Aug; 269():6-14. PubMed ID: 24768640
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heat shock protein 90 maintains the tumour-like character of rheumatoid synovial cells by stabilizing integrin-linked kinase, extracellular signal-regulated kinase and protein kinase B.
    Hashiramoto A; Murata M; Kawazoe T; Yoshida K; Akiyama C; Shiozawa K; Shiozawa S
    Rheumatology (Oxford); 2011 May; 50(5):852-61. PubMed ID: 21177334
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuroprotection of ethanol against ischemia/reperfusion-induced brain injury through decreasing c-Jun N-terminal kinase 3 (JNK3) activation by enhancing GABA release.
    Qi SH; Liu Y; Hao LY; Guan QH; Gu YH; Zhang J; Yan H; Wang M; Zhang GY
    Neuroscience; 2010 Jun; 167(4):1125-37. PubMed ID: 20219637
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activation.
    Koga F; Xu W; Karpova TS; McNally JG; Baron R; Neckers L
    Proc Natl Acad Sci U S A; 2006 Jul; 103(30):11318-22. PubMed ID: 16844778
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neuroprotection of preconditioning against ischemic brain injury in rat hippocampus through inhibition of the assembly of GluR6-PSD95-mixed lineage kinase 3 signaling module via nuclear and non-nuclear pathways.
    Du Y; Li C; Hu WW; Song YJ; Zhang GY
    Neuroscience; 2009 Jun; 161(2):370-80. PubMed ID: 19328223
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation.
    Hui L; Pei DS; Zhang QG; Guan QH; Zhang GY
    Brain Res; 2005 Aug; 1052(1):1-9. PubMed ID: 16018989
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Akt inhibits MLK3/JNK3 signaling by inactivating Rac1: a protective mechanism against ischemic brain injury.
    Zhang QG; Wang XT; Han D; Yin XH; Zhang GY; Xu TL
    J Neurochem; 2006 Sep; 98(6):1886-98. PubMed ID: 16831194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling.
    Zhang H; Wu W; Du Y; Santos SJ; Conrad SE; Watson JT; Grammatikakis N; Gallo KA
    J Biol Chem; 2004 May; 279(19):19457-63. PubMed ID: 15001580
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The potential role of HO-1 in regulating the MLK3-MKK7-JNK3 module scaffolded by JIP1 during cerebral ischemia/reperfusion in rats.
    Song YJ; Dai CX; Li M; Cui MM; Ding X; Zhao XF; Wang CL; Li ZL; Guo MY; Fu YY; Wen XR; Qi DS; Wang YL
    Behav Brain Res; 2019 Feb; 359():528-535. PubMed ID: 30412737
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation.
    Jeon YK; Park CH; Kim KY; Li YC; Kim J; Kim YA; Paik JH; Park BK; Kim CW; Kim YN
    J Pathol; 2007 Oct; 213(2):170-9. PubMed ID: 17768706
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.