264 related articles for article (PubMed ID: 18778087)
1. Identification of cytochrome P450 enzymes involved in the metabolism of the designer drugs N-(1-phenylcyclohexyl)-3-ethoxypropanamine and N-(1-phenylcyclohexyl)-3-methoxypropanamine.
Sauer C; Peters FT; Schwaninger AE; Meyer MR; Maurer HH
Chem Res Toxicol; 2008 Oct; 21(10):1949-55. PubMed ID: 18778087
[TBL] [Abstract][Full Text] [Related]
2. Investigations on the cytochrome P450 (CYP) isoenzymes involved in the metabolism of the designer drugs N-(1-phenyl cyclohexyl)-2-ethoxyethanamine and N-(1-phenylcyclohexyl)-2-methoxyethanamine.
Sauer C; Peters FT; Schwaninger AE; Meyer MR; Maurer HH
Biochem Pharmacol; 2009 Feb; 77(3):444-50. PubMed ID: 19022226
[TBL] [Abstract][Full Text] [Related]
3. Identification of cytochrome P450 enzymes involved in the metabolism of the new designer drug 4'-methyl-alpha-pyrrolidinobutyrophenone.
Peters FT; Meyer MR; Theobald DS; Maurer HH
Drug Metab Dispos; 2008 Jan; 36(1):163-8. PubMed ID: 17962373
[TBL] [Abstract][Full Text] [Related]
4. Metabolism and toxicological detection of the designer drug N-(1-phenylcyclohexyl)-3-methoxypropanamine (PCMPA) in rat urine using gas chromatography-mass spectrometry.
Sauer C; Peters FT; Staack RF; Fritschi G; Maurer HH
Forensic Sci Int; 2008 Oct; 181(1-3):47-51. PubMed ID: 18922655
[TBL] [Abstract][Full Text] [Related]
5. Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.
Staack RF; Theobald DS; Paul LD; Springer D; Kraemer T; Maurer HH
Drug Metab Dispos; 2004 Apr; 32(4):379-81. PubMed ID: 15039289
[TBL] [Abstract][Full Text] [Related]
6. Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes.
Iribarne C; Berthou F; Baird S; Dréano Y; Picart D; Bail JP; Beaune P; Ménez JF
Chem Res Toxicol; 1996 Mar; 9(2):365-73. PubMed ID: 8839037
[TBL] [Abstract][Full Text] [Related]
7. The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone.
Moody DE; Alburges ME; Parker RJ; Collins JM; Strong JM
Drug Metab Dispos; 1997 Dec; 25(12):1347-53. PubMed ID: 9394023
[TBL] [Abstract][Full Text] [Related]
8. Identification of the human liver microsomal cytochrome P450s involved in the metabolism of N-nitrosodi-n-propylamine.
Teiber JF; Hollenberg PF
Carcinogenesis; 2000 Aug; 21(8):1559-66. PubMed ID: 10910959
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and characterization of 7-methoxy-4-(aminomethyl)coumarin as a novel and selective cytochrome P450 2D6 substrate suitable for high-throughput screening.
Onderwater RC; Venhorst J; Commandeur JN; Vermeulen NP
Chem Res Toxicol; 1999 Jul; 12(7):555-9. PubMed ID: 10409393
[TBL] [Abstract][Full Text] [Related]
10. Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites.
Avent KM; DeVoss JJ; Gillam EM
Chem Res Toxicol; 2006 Jul; 19(7):914-20. PubMed ID: 16841959
[TBL] [Abstract][Full Text] [Related]
11. Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions.
Labroo RB; Paine MF; Thummel KE; Kharasch ED
Drug Metab Dispos; 1997 Sep; 25(9):1072-80. PubMed ID: 9311623
[TBL] [Abstract][Full Text] [Related]
12. Involvement of multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes in the in vitro metabolism of muraglitazar.
Zhang D; Wang L; Chandrasena G; Ma L; Zhu M; Zhang H; Davis CD; Humphreys WG
Drug Metab Dispos; 2007 Jan; 35(1):139-49. PubMed ID: 17062778
[TBL] [Abstract][Full Text] [Related]
13. New designer drug N-(1-phenylcyclohexyl)-3-ethoxypropanamine (PCEPA): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques.
Sauer C; Peters FT; Staack RF; Fritschi G; Maurer HH
J Mass Spectrom; 2006 Aug; 41(8):1014-29. PubMed ID: 16817170
[TBL] [Abstract][Full Text] [Related]
14. Dimethocaine, a synthetic cocaine derivative: studies on its in vitro metabolism catalyzed by P450s and NAT2.
Meyer MR; Lindauer C; Maurer HH
Toxicol Lett; 2014 Feb; 225(1):139-46. PubMed ID: 24309420
[TBL] [Abstract][Full Text] [Related]
15. A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation.
Grillo MP; Ma J; Teffera Y; Waldon DJ
Drug Metab Dispos; 2008 Sep; 36(9):1740-4. PubMed ID: 18541695
[TBL] [Abstract][Full Text] [Related]
16. Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism.
Yang TJ; Krausz KW; Sai Y; Gonzalez FJ; Gelboin HV
Drug Metab Dispos; 1999 Jan; 27(1):102-9. PubMed ID: 9884317
[TBL] [Abstract][Full Text] [Related]
17. Cytochrome P450 inhibition using recombinant proteins and mass spectrometry/multiple reaction monitoring technology in a cassette incubation.
Weaver R; Graham KS; Beattie IG; Riley RJ
Drug Metab Dispos; 2003 Jul; 31(7):955-66. PubMed ID: 12814974
[TBL] [Abstract][Full Text] [Related]
18. Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.
Pearce RE; Gotschall RR; Kearns GL; Leeder JS
Drug Metab Dispos; 2001 Dec; 29(12):1548-54. PubMed ID: 11717173
[TBL] [Abstract][Full Text] [Related]
19. Stereoselective metabolism of cisapride and enantiomer-enantiomer interaction in human cytochrome P450 enzymes: major role of CYP3A.
Desta Z; Soukhova N; Morocho AM; Flockhart DA
J Pharmacol Exp Ther; 2001 Aug; 298(2):508-20. PubMed ID: 11454912
[TBL] [Abstract][Full Text] [Related]
20. Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4.
Komatsu T; Yamazaki H; Asahi S; Gillam EM; Guengerich FP; Nakajima M; Yokoi T
Drug Metab Dispos; 2000 Nov; 28(11):1361-8. PubMed ID: 11038165
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]