248 related articles for article (PubMed ID: 18778766)
1. ssDNA fragments induce cell senescence by telomere uncapping.
Tsolou A; Passos JF; Nelson G; Arai Y; Zglinicki Tv
Exp Gerontol; 2008 Oct; 43(10):892-9. PubMed ID: 18778766
[TBL] [Abstract][Full Text] [Related]
2. Human cell senescence as a DNA damage response.
von Zglinicki T; Saretzki G; Ladhoff J; d'Adda di Fagagna F; Jackson SP
Mech Ageing Dev; 2005 Jan; 126(1):111-7. PubMed ID: 15610769
[TBL] [Abstract][Full Text] [Related]
3. Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.
Hockemeyer D; Daniels JP; Takai H; de Lange T
Cell; 2006 Jul; 126(1):63-77. PubMed ID: 16839877
[TBL] [Abstract][Full Text] [Related]
4. A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.
Brassart B; Gomez D; De Cian A; Paterski R; Montagnac A; Qui KH; Temime-Smaali N; Trentesaux C; Mergny JL; Gueritte F; Riou JF
Mol Pharmacol; 2007 Sep; 72(3):631-40. PubMed ID: 17586599
[TBL] [Abstract][Full Text] [Related]
5. Telomeric 3'-overhang length is associated with the size of telomeres.
Rahman R; Forsyth NR; Cui W
Exp Gerontol; 2008 Apr; 43(4):258-65. PubMed ID: 18280685
[TBL] [Abstract][Full Text] [Related]
6. Functional human telomeres are recognized as DNA damage in G2 of the cell cycle.
Verdun RE; Crabbe L; Haggblom C; Karlseder J
Mol Cell; 2005 Nov; 20(4):551-61. PubMed ID: 16307919
[TBL] [Abstract][Full Text] [Related]
7. PTOP interacts with POT1 and regulates its localization to telomeres.
Liu D; Safari A; O'Connor MS; Chan DW; Laegeler A; Qin J; Songyang Z
Nat Cell Biol; 2004 Jul; 6(7):673-80. PubMed ID: 15181449
[TBL] [Abstract][Full Text] [Related]
8. Irreversible cellular senescence induced by prolonged exposure to H2O2 involves DNA-damage-and-repair genes and telomere shortening.
Duan J; Duan J; Zhang Z; Tong T
Int J Biochem Cell Biol; 2005 Jul; 37(7):1407-20. PubMed ID: 15833273
[TBL] [Abstract][Full Text] [Related]
9. Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.
Saretzki G; Sitte N; Merkel U; Wurm RE; von Zglinicki T
Oncogene; 1999 Sep; 18(37):5148-58. PubMed ID: 10498864
[TBL] [Abstract][Full Text] [Related]
10. The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells.
Gomez D; O'Donohue MF; Wenner T; Douarre C; Macadré J; Koebel P; Giraud-Panis MJ; Kaplan H; Kolkes A; Shin-ya K; Riou JF
Cancer Res; 2006 Jul; 66(14):6908-12. PubMed ID: 16849533
[TBL] [Abstract][Full Text] [Related]
11. Senescence as an anticancer mechanism.
Hornsby PJ
J Clin Oncol; 2007 May; 25(14):1852-7. PubMed ID: 17488983
[TBL] [Abstract][Full Text] [Related]
12. Signaling pathway requirements for induction of senescence by telomere homolog oligonucleotides.
Li GZ; Eller MS; Hanna K; Gilchrest BA
Exp Cell Res; 2004 Dec; 301(2):189-200. PubMed ID: 15530855
[TBL] [Abstract][Full Text] [Related]
13. Telomerase- and capping-independent yeast survivors with alternate telomere states.
Larrivée M; Wellinger RJ
Nat Cell Biol; 2006 Jul; 8(7):741-7. PubMed ID: 16767083
[TBL] [Abstract][Full Text] [Related]
14. Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants.
Zubko MK; Guillard S; Lydall D
Genetics; 2004 Sep; 168(1):103-15. PubMed ID: 15454530
[TBL] [Abstract][Full Text] [Related]
15. TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblasts.
Richter T; Saretzki G; Nelson G; Melcher M; Olijslagers S; von Zglinicki T
Mech Ageing Dev; 2007 Apr; 128(4):340-5. PubMed ID: 17395247
[TBL] [Abstract][Full Text] [Related]
16. When the caps fall off: responses to telomere uncapping in yeast.
Wellinger RJ
FEBS Lett; 2010 Sep; 584(17):3734-40. PubMed ID: 20600003
[TBL] [Abstract][Full Text] [Related]
17. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.
Wu L; Multani AS; He H; Cosme-Blanco W; Deng Y; Deng JM; Bachilo O; Pathak S; Tahara H; Bailey SM; Deng Y; Behringer RR; Chang S
Cell; 2006 Jul; 126(1):49-62. PubMed ID: 16839876
[TBL] [Abstract][Full Text] [Related]
18. Telomere dysfunction in human keratinocytes elicits senescence and a novel transcription profile.
Minty F; Thurlow JK; Harrison PR; Parkinson EK
Exp Cell Res; 2008 Aug; 314(13):2434-47. PubMed ID: 18589416
[TBL] [Abstract][Full Text] [Related]
19. Oxygen free radicals in cell senescence: are they signal transducers?
Passos JF; Von Zglinicki T
Free Radic Res; 2006 Dec; 40(12):1277-83. PubMed ID: 17090417
[TBL] [Abstract][Full Text] [Related]
20. Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.
Gomez D; Wenner T; Brassart B; Douarre C; O'Donohue MF; El Khoury V; Shin-Ya K; Morjani H; Trentesaux C; Riou JF
J Biol Chem; 2006 Dec; 281(50):38721-9. PubMed ID: 17050546
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
