150 related articles for article (PubMed ID: 18789701)
1. Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3'-azido, 3'-deoxythymidine: a QSAR investigation.
Song Y; Chan JM; Tovian Z; Secrest A; Nagy E; Krysiak K; Bergan K; Parniak MA; Oldfield E
Bioorg Med Chem; 2008 Oct; 16(19):8959-67. PubMed ID: 18789701
[TBL] [Abstract][Full Text] [Related]
2. 3'-Azido-3'-deoxythymidine-(5')-tetraphospho-(5')-adenosine, the product of ATP-mediated excision of chain-terminating AZTMP, is a potent chain-terminating substrate for HIV-1 reverse transcriptase.
Dharmasena S; Pongracz Z; Arnold E; Sarafianos SG; Parniak MA
Biochemistry; 2007 Jan; 46(3):828-36. PubMed ID: 17223704
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3'-azido-3'-deoxythymidine with nonnucleoside inhibitors.
Cruchaga C; Odriozola L; Andréola M; Tarrago-Litvak L; Martínez-Irujo JJ
Biochemistry; 2005 Mar; 44(9):3535-46. PubMed ID: 15736963
[TBL] [Abstract][Full Text] [Related]
4. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
[TBL] [Abstract][Full Text] [Related]
5. Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3'-azido-3'-deoxythymidine (AZT)-resistant polymerase to AZT-5'-triphosphate.
Odriozola L; Cruchaga C; Andréola M; Dollé V; Nguyen CH; Tarrago-Litvak L; Pérez-Mediavilla A; Martínez-Irujo JJ
J Biol Chem; 2003 Oct; 278(43):42710-6. PubMed ID: 12917424
[TBL] [Abstract][Full Text] [Related]
6. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2001 May; 75(10):4832-42. PubMed ID: 11312355
[TBL] [Abstract][Full Text] [Related]
7. Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates.
Meyer PR; Matsuura SE; Schinazi RF; So AG; Scott WA
Antimicrob Agents Chemother; 2000 Dec; 44(12):3465-72. PubMed ID: 11083661
[TBL] [Abstract][Full Text] [Related]
8. The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Apr; 76(7):3248-56. PubMed ID: 11884549
[TBL] [Abstract][Full Text] [Related]
9. The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Selmi B; Deval J; Alvarez K; Boretto J; Sarfati S; Guerreiro C; Canard B
J Biol Chem; 2003 Oct; 278(42):40464-72. PubMed ID: 12902345
[TBL] [Abstract][Full Text] [Related]
10. Structural basis of HIV-1 resistance to AZT by excision.
Tu X; Das K; Han Q; Bauman JD; Clark AD; Hou X; Frenkel YV; Gaffney BL; Jones RA; Boyer PL; Hughes SH; Sarafianos SG; Arnold E
Nat Struct Mol Biol; 2010 Oct; 17(10):1202-9. PubMed ID: 20852643
[TBL] [Abstract][Full Text] [Related]
11. Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Canard B; Sarfati SR; Richardson CC
J Biol Chem; 1998 Jun; 273(23):14596-604. PubMed ID: 9603976
[TBL] [Abstract][Full Text] [Related]
12. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
Periclou AP; Nandy P; Avramis VI
In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
[TBL] [Abstract][Full Text] [Related]
13. A pyrophosphatase activity associated with purified HIV-1 particles.
Ducloux C; Mougel M; Goldschmidt V; Didierlaurent L; Marquet R; Isel C
Biochimie; 2012 Dec; 94(12):2498-507. PubMed ID: 22766015
[TBL] [Abstract][Full Text] [Related]
14. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
Shaw-Reid CA; Feuston B; Munshi V; Getty K; Krueger J; Hazuda DJ; Parniak MA; Miller MD; Lewis D
Biochemistry; 2005 Feb; 44(5):1595-606. PubMed ID: 15683243
[TBL] [Abstract][Full Text] [Related]
15. Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
Schneider A; Corona A; Spöring I; Jordan M; Buchholz B; Maccioni E; Di Santo R; Bodem J; Tramontano E; Wöhrl BM
Nucleic Acids Res; 2016 Mar; 44(5):2310-22. PubMed ID: 26850643
[TBL] [Abstract][Full Text] [Related]
16. Relationship between 3'-azido-3'-deoxythymidine resistance and primer unblocking activity in foscarnet-resistant mutants of human immunodeficiency virus type 1 reverse transcriptase.
Meyer PR; Matsuura SE; Zonarich D; Chopra RR; Pendarvis E; Bazmi HZ; Mellors JW; Scott WA
J Virol; 2003 Jun; 77(11):6127-37. PubMed ID: 12743270
[TBL] [Abstract][Full Text] [Related]
17. AZT resistance of simian foamy virus reverse transcriptase is based on the excision of AZTMP in the presence of ATP.
Hartl MJ; Kretzschmar B; Frohn A; Nowrouzi A; Rethwilm A; Wöhrl BM
Nucleic Acids Res; 2008 Feb; 36(3):1009-16. PubMed ID: 18096624
[TBL] [Abstract][Full Text] [Related]
18. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
Kerr SG; Anderson KS
Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
[TBL] [Abstract][Full Text] [Related]
19. Selective excision of chain-terminating nucleotides by HIV-1 reverse transcriptase with phosphonoformate as substrate.
Cruchaga C; Ansó E; Rouzaut A; Martínez-Irujo JJ
J Biol Chem; 2006 Sep; 281(38):27744-52. PubMed ID: 16829515
[TBL] [Abstract][Full Text] [Related]
20. Implication of the tRNA initiation step for human immunodeficiency virus type 1 reverse transcriptase in the mechanism of 3'-azido-3'-deoxythymidine (AZT) resistance.
Vaccaro JA; Anderson KS
Biochemistry; 1998 Oct; 37(40):14189-94. PubMed ID: 9760256
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]