993 related articles for article (PubMed ID: 18790133)
21. Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors.
Xin Z; Zhao H; Serby MD; Liu B; Liu M; Szczepankiewicz BG; Nelson LT; Smith HT; Suhar TS; Janis RS; Cao N; Camp HS; Collins CA; Sham HL; Surowy TK; Liu G
Bioorg Med Chem Lett; 2008 Aug; 18(15):4298-302. PubMed ID: 18632269
[TBL] [Abstract][Full Text] [Related]
22. A visible wavelength spectrophotometric assay suitable for high-throughput screening of 3-hydroxy-3-methylglutaryl-CoA synthase.
Andrew Skaff D; Miziorko HM
Anal Biochem; 2010 Jan; 396(1):96-102. PubMed ID: 19706283
[TBL] [Abstract][Full Text] [Related]
23. Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: from systemic to liver-targeting inhibitors.
Ramtohul YK; Powell D; Leclerc JP; Leger S; Oballa R; Black C; Isabel E; Li CS; Crane S; Robichaud J; Guay J; Guiral S; Zhang L; Huang Z
Bioorg Med Chem Lett; 2011 Oct; 21(19):5692-6. PubMed ID: 21871798
[TBL] [Abstract][Full Text] [Related]
24. Expression and regulation of delta5-desaturase, delta6-desaturase, stearoyl-coenzyme A (CoA) desaturase 1, and stearoyl-CoA desaturase 2 in rat testis.
Saether T; Tran TN; Rootwelt H; Christophersen BO; Haugen TB
Biol Reprod; 2003 Jul; 69(1):117-24. PubMed ID: 12606372
[TBL] [Abstract][Full Text] [Related]
25. Thiazole analog as stearoyl-CoA desaturase 1 inhibitor.
Li CS; Belair L; Guay J; Murgasva R; Sturkenboom W; Ramtohul YK; Zhang L; Huang Z
Bioorg Med Chem Lett; 2009 Sep; 19(17):5214-7. PubMed ID: 19632834
[TBL] [Abstract][Full Text] [Related]
26. Stearoyl-CoA desaturase in mitochondrial membrane fractions.
Mugnai G; Boddi V
Ital J Biochem; 1977; 26(3):245-53. PubMed ID: 21148
[TBL] [Abstract][Full Text] [Related]
27. A microsomal endopeptidase from liver that preferentially degrades stearoyl-CoA desaturase.
Heinemann FS; Mziaut H; Korza G; Ozols J
Biochemistry; 2003 Jun; 42(23):6929-37. PubMed ID: 12795587
[TBL] [Abstract][Full Text] [Related]
28. Thia fatty acids as substrates and inhibitors of stearoyl-CoA desaturase.
Høvik KE; Spydevold OS; Bremer J
Biochim Biophys Acta; 1997 Nov; 1349(3):251-6. PubMed ID: 9434139
[TBL] [Abstract][Full Text] [Related]
29. Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy.
Roongta UV; Pabalan JG; Wang X; Ryseck RP; Fargnoli J; Henley BJ; Yang WP; Zhu J; Madireddi MT; Lawrence RM; Wong TW; Rupnow BA
Mol Cancer Res; 2011 Nov; 9(11):1551-61. PubMed ID: 21954435
[TBL] [Abstract][Full Text] [Related]
30. Plasma-based approach to measure target engagement for liver-targeting stearoyl-CoA desaturase 1 inhibitors.
Landry F; Chan CC; Huang Z; Leclair G; Li CS; Oballa R; Zhang L; Bateman K
J Lipid Res; 2011 Aug; 52(8):1494-9. PubMed ID: 21642745
[TBL] [Abstract][Full Text] [Related]
31. Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin.
Mauvoisin D; Prévost M; Ducheix S; Arnaud MP; Mounier C
Mol Cell Endocrinol; 2010 May; 319(1-2):116-28. PubMed ID: 20109524
[TBL] [Abstract][Full Text] [Related]
32. Potent, orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors.
Koltun DO; Zilbershtein TM; Migulin VA; Vasilevich NI; Parkhill EQ; Glushkov AI; McGregor MJ; Brunn SA; Chu N; Hao J; Mollova N; Leung K; Chisholm JW; Zablocki J
Bioorg Med Chem Lett; 2009 Aug; 19(15):4070-4. PubMed ID: 19577469
[TBL] [Abstract][Full Text] [Related]
33. Recent progress in the discovery and development of stearoyl CoA desaturase inhibitors.
Uto Y
Chem Phys Lipids; 2016 May; 197():3-12. PubMed ID: 26344107
[TBL] [Abstract][Full Text] [Related]
34. Hormonal and nutritional regulation of SCD1 gene expression.
Mauvoisin D; Mounier C
Biochimie; 2011 Jan; 93(1):78-86. PubMed ID: 20713121
[TBL] [Abstract][Full Text] [Related]
35. Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis.
Scaglia N; Igal RA
Int J Oncol; 2008 Oct; 33(4):839-50. PubMed ID: 18813799
[TBL] [Abstract][Full Text] [Related]
36. [Stearoyl-CoA desaturase in the control of metabolic homeostasis].
Dobrzyń P
Postepy Biochem; 2012; 58(2):166-74. PubMed ID: 23214140
[TBL] [Abstract][Full Text] [Related]
37. 2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitors.
Powell DA; Ramtohul Y; Lebrun ME; Oballa R; Bhat S; Falgueyret JP; Guiral S; Huang Z; Skorey K; Tawa P; Zhang L
Bioorg Med Chem Lett; 2010 Nov; 20(22):6366-9. PubMed ID: 20933412
[TBL] [Abstract][Full Text] [Related]
38. A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC.
Su C; Gullberg H; Simko H; Luthman M; Edlund PO; Lundbäck T
J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Sep; 878(26):2427-32. PubMed ID: 20732836
[TBL] [Abstract][Full Text] [Related]
39. Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c.
Biddinger SB; Miyazaki M; Boucher J; Ntambi JM; Kahn CR
Diabetes; 2006 Jul; 55(7):2032-41. PubMed ID: 16804073
[TBL] [Abstract][Full Text] [Related]
40. Discovery and pharmacological characterization of SAR707 as novel and selective small molecule inhibitor of stearoyl-CoA desaturase (SCD1).
Voss MD; Zoller G; Matter H; Herling AW; Biemer-Daub G; Pfenninger A; Haag-Diergarten S; Keil S; Kohlmann M; Schmidts HL
Eur J Pharmacol; 2013 May; 707(1-3):140-6. PubMed ID: 23524088
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
