256 related articles for article (PubMed ID: 18790746)
1. Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.
Park MA; Zhang G; Mitchell C; Rahmani M; Hamed H; Hagan MP; Yacoub A; Curiel DT; Fisher PB; Grant S; Dent P
Mol Cancer Ther; 2008 Sep; 7(9):2633-48. PubMed ID: 18790746
[TBL] [Abstract][Full Text] [Related]
2. 17-allylamino-17-demethoxygeldanamycin and MEK1/2 inhibitors kill GI tumor cells via Ca2+-dependent suppression of GRP78/BiP and induction of ceramide and reactive oxygen species.
Walker T; Mitchell C; Park MA; Yacoub A; Rahmani M; Häussinger D; Reinehr R; Voelkel-Johnson C; Fisher PB; Grant S; Dent P
Mol Cancer Ther; 2010 May; 9(5):1378-95. PubMed ID: 20442308
[TBL] [Abstract][Full Text] [Related]
3. 17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines.
Mitchell C; Park MA; Zhang G; Han SI; Harada H; Franklin RA; Yacoub A; Li PL; Hylemon PB; Grant S; Dent P
Mol Cancer Ther; 2007 Feb; 6(2):618-32. PubMed ID: 17308059
[TBL] [Abstract][Full Text] [Related]
4. HSP90 inhibitors strengthen extracellular ATP-stimulated synthesis of interleukin-6 in osteoblasts: Amplification of p38 MAP kinase.
Hioki T; Tokuda H; Nakashima D; Fujita K; Kawabata T; Sakai G; Kim W; Tachi J; Tanabe K; Matsushima-Nishiwaki R; Otsuka T; Iida H; Kozawa O
Cell Biochem Funct; 2021 Jan; 39(1):88-97. PubMed ID: 32567086
[TBL] [Abstract][Full Text] [Related]
5. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
Qiao L; Studer E; Leach K; McKinstry R; Gupta S; Decker R; Kukreja R; Valerie K; Nagarkatti P; El Deiry W; Molkentin J; Schmidt-Ullrich R; Fisher PB; Grant S; Hylemon PB; Dent P
Mol Biol Cell; 2001 Sep; 12(9):2629-45. PubMed ID: 11553704
[TBL] [Abstract][Full Text] [Related]
6. Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.
Zhang G; Park MA; Mitchell C; Hamed H; Rahmani M; Martin AP; Curiel DT; Yacoub A; Graf M; Lee R; Roberts JD; Fisher PB; Grant S; Dent P
Clin Cancer Res; 2008 Sep; 14(17):5385-99. PubMed ID: 18765530
[TBL] [Abstract][Full Text] [Related]
7. Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors.
Vaseva AV; Yallowitz AR; Marchenko ND; Xu S; Moll UM
Cell Death Dis; 2011 May; 2(5):e156. PubMed ID: 21562588
[TBL] [Abstract][Full Text] [Related]
8. Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation.
Kober AM; Legewie S; Pforr C; Fricker N; Eils R; Krammer PH; Lavrik IN
Cell Death Dis; 2011 Oct; 2(10):e212. PubMed ID: 21975294
[TBL] [Abstract][Full Text] [Related]
9. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
Yu C; Krystal G; Varticovksi L; McKinstry R; Rahmani M; Dent P; Grant S
Cancer Res; 2002 Jan; 62(1):188-99. PubMed ID: 11782377
[TBL] [Abstract][Full Text] [Related]
10. Sorafenib and HDAC inhibitors synergize with TRAIL to kill tumor cells.
Hamed HA; Yamaguchi Y; Fisher PB; Grant S; Dent P
J Cell Physiol; 2013 Oct; 228(10):1996-2005. PubMed ID: 23674352
[TBL] [Abstract][Full Text] [Related]
11. A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
Park MA; Hamed HA; Mitchell C; Cruickshanks N; Dash R; Allegood J; Dmitriev IP; Tye G; Ogretmen B; Spiegel S; Yacoub A; Grant S; Curiel DT; Fisher PB; Dent P
Mol Pharmacol; 2011 Mar; 79(3):368-80. PubMed ID: 21119025
[TBL] [Abstract][Full Text] [Related]
12. MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.
Park MA; Walker T; Martin AP; Allegood J; Vozhilla N; Emdad L; Sarkar D; Rahmani M; Graf M; Yacoub A; Koumenis C; Spiegel S; Curiel DT; Voelkel-Johnson C; Grant S; Fisher PB; Dent P
Mol Cancer Ther; 2009 May; 8(5):1280-91. PubMed ID: 19417161
[TBL] [Abstract][Full Text] [Related]
13. Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.
Walker T; Mitchell C; Park MA; Yacoub A; Graf M; Rahmani M; Houghton PJ; Voelkel-Johnson C; Grant S; Dent P
Mol Pharmacol; 2009 Aug; 76(2):342-55. PubMed ID: 19483104
[TBL] [Abstract][Full Text] [Related]
14. OSU-03012 interacts with lapatinib to kill brain cancer cells.
Booth L; Cruickshanks N; Ridder T; Chen CS; Grant S; Dent P
Cancer Biol Ther; 2012 Dec; 13(14):1501-11. PubMed ID: 22990204
[TBL] [Abstract][Full Text] [Related]
15. Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.
Yacoub A; Liu R; Park MA; Hamed HA; Dash R; Schramm DN; Sarkar D; Dimitriev IP; Bell JK; Grant S; Farrell NP; Curiel DT; Fisher PB; Dent P
Mol Pharmacol; 2010 Feb; 77(2):298-310. PubMed ID: 19910452
[TBL] [Abstract][Full Text] [Related]
16. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
Ou YC; Yang CR; Cheng CL; Raung SL; Hung YY; Chen CJ
Eur J Pharmacol; 2007 Jun; 563(1-3):49-60. PubMed ID: 17341418
[TBL] [Abstract][Full Text] [Related]
17. Phosphatidylinositol 3-kinase/Akt positively regulates Fas (CD95)-mediated apoptosis in epidermal Cl41 cells.
Lu B; Wang L; Stehlik C; Medan D; Huang C; Hu S; Chen F; Shi X; Rojanasakul Y
J Immunol; 2006 Jun; 176(11):6785-93. PubMed ID: 16709838
[TBL] [Abstract][Full Text] [Related]
18. Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death.
Pritchard JR; Cosgrove BD; Hemann MT; Griffith LG; Wands JR; Lauffenburger DA
Mol Cancer Ther; 2009 Aug; 8(8):2183-92. PubMed ID: 19671754
[TBL] [Abstract][Full Text] [Related]
19. Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Vrana JA; Grant S
Blood; 2001 Apr; 97(7):2105-14. PubMed ID: 11264178
[TBL] [Abstract][Full Text] [Related]
20. HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells.
Adachi S; Yasuda I; Nakashima M; Yamauchi T; Yamauchi J; Natsume H; Moriwaki H; Kozawa O
Oncol Rep; 2010 Jun; 23(6):1709-14. PubMed ID: 20428829
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
