BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 18798648)

  • 21. Interactions of key charged residues contributing to selective block of neuronal sodium channels by μ-conotoxin KIIIA.
    McArthur JR; Singh G; McMaster D; Winkfein R; Tieleman DP; French RJ
    Mol Pharmacol; 2011 Oct; 80(4):573-84. PubMed ID: 21709136
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors.
    Favreau P; Benoit E; Hocking HG; Carlier L; D' hoedt D; Leipold E; Markgraf R; Schlumberger S; Córdova MA; Gaertner H; Paolini-Bertrand M; Hartley O; Tytgat J; Heinemann SH; Bertrand D; Boelens R; Stöcklin R; Molgó J
    Br J Pharmacol; 2012 Jul; 166(5):1654-68. PubMed ID: 22229737
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Binding modes of μ-conotoxin to the bacterial sodium channel (NaVAb).
    Chen R; Chung SH
    Biophys J; 2012 Feb; 102(3):483-8. PubMed ID: 22325270
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels.
    Hill JM; Alewood PF; Craik DJ
    Biochemistry; 1996 Jul; 35(27):8824-35. PubMed ID: 8688418
    [TBL] [Abstract][Full Text] [Related]  

  • 25. μ-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels.
    Zhang MM; Han TS; Olivera BM; Bulaj G; Yoshikami D
    Biochemistry; 2010 Jun; 49(23):4804-12. PubMed ID: 20459109
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus.
    Holford M; Zhang MM; Gowd KH; Azam L; Green BR; Watkins M; Ownby JP; Yoshikami D; Bulaj G; Olivera BM
    Toxicon; 2009 Jan; 53(1):90-8. PubMed ID: 18950653
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Expanding chemical diversity of conotoxins: peptoid-peptide chimeras of the sodium channel blocker μ-KIIIA and its selenopeptide analogues.
    Walewska A; Han TS; Zhang MM; Yoshikami D; Bulaj G; Rolka K
    Eur J Med Chem; 2013 Jul; 65():144-50. PubMed ID: 23707919
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A novel μ-conotoxin from worm-hunting Conus tessulatus that selectively inhibit rat TTX-resistant sodium currents.
    Yang M; Zhao S; Min X; Shao M; Chen Y; Chen Z; Zhou M
    Toxicon; 2017 May; 130():11-18. PubMed ID: 28219625
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry.
    Hill JM; Alewood PF; Craik DJ
    Structure; 1997 Apr; 5(4):571-83. PubMed ID: 9115446
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.
    Daly NL; Ekberg JA; Thomas L; Adams DJ; Lewis RJ; Craik DJ
    J Biol Chem; 2004 Jun; 279(24):25774-82. PubMed ID: 15044438
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Dependence of mu-conotoxin block of sodium channels on ionic strength but not on the permeating [Na+]: implications for the distinctive mechanistic interactions between Na+ and K+ channel pore-blocking toxins and their molecular targets.
    Li RA; Hui K; French RJ; Sato K; Henrikson CA; Tomaselli GF; Marbán E
    J Biol Chem; 2003 Aug; 278(33):30912-9. PubMed ID: 12764145
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis, and mechanism of action of novel μ-conotoxin KIIIA analogues for inhibition of the voltage-gated sodium channel Na
    Zhao Z; Pan T; Chen S; Harvey PJ; Zhang J; Li X; Yang M; Huang L; Wang S; Craik DJ; Jiang T; Yu R
    J Biol Chem; 2023 Apr; 299(4):103068. PubMed ID: 36842500
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels.
    Zhang MM; Fiedler B; Green BR; Catlin P; Watkins M; Garrett JE; Smith BJ; Yoshikami D; Olivera BM; Bulaj G
    Biochemistry; 2006 Mar; 45(11):3723-32. PubMed ID: 16533055
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Multiple, distributed interactions of μ-conotoxin PIIIA associated with broad targeting among voltage-gated sodium channels.
    McArthur JR; Ostroumov V; Al-Sabi A; McMaster D; French RJ
    Biochemistry; 2011 Jan; 50(1):116-24. PubMed ID: 21110521
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin BuIIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3.
    Green BR; Zhang MM; Chhabra S; Robinson SD; Wilson MJ; Redding A; Olivera BM; Yoshikami D; Bulaj G; Norton RS
    FEBS J; 2014 Jul; 281(13):2885-98. PubMed ID: 24814369
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Computational Design of High-Affinity Blockers for Sodium Channel Na
    Meng G; Kuyucak S
    Mar Drugs; 2022 Feb; 20(2):. PubMed ID: 35200683
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activity.
    Green BR; Bulaj G; Norton RS
    Future Med Chem; 2014 Oct; 6(15):1677-98. PubMed ID: 25406007
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Mechanism of μ-conotoxin PIIIA binding to the voltage-gated Na+ channel NaV1.4.
    Chen R; Robinson A; Chung SH
    PLoS One; 2014; 9(3):e93267. PubMed ID: 24676211
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Roles of basic amino acid residues in the activity of μ-conotoxin GIIIA and GIIIB, peptide blockers of muscle sodium channels.
    Sato K; Yamaguchi Y; Ishida Y; Ohizumi Y
    Chem Biol Drug Des; 2015 Apr; 85(4):488-93. PubMed ID: 25228447
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Charge conversion enables quantification of the proximity between a normally-neutral mu-conotoxin (GIIIA) site and the Na+ channel pore.
    Li RA; Sato K; Kodama K; Kohno T; Xue T; Tomaselli GF; Marbán E
    FEBS Lett; 2002 Jan; 511(1-3):159-64. PubMed ID: 11821068
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.