BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

491 related articles for article (PubMed ID: 18799315)

  • 1. Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.
    Pretorius A; Ogunrombi MO; Terre'blanche G; Castagnoli N; Bergh JJ; Petzer JP
    Bioorg Med Chem; 2008 Oct; 16(19):8813-7. PubMed ID: 18799315
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neurotoxicity studies with the monoamine oxidase B substrate 1-methyl-3-phenyl-3-pyrroline.
    Ogunrombi MO; Malan SF; Terre'Blanche G; Castagnoli K; Castagnoli N; Bergh JJ; Petzer JP
    Life Sci; 2007 Jul; 81(6):458-67. PubMed ID: 17655878
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B.
    Pretorius A; Ogunrombi MO; Fourie H; Terre'blanche G; Castagnoli N; Bergh JJ; Petzer JP
    Bioorg Med Chem; 2010 Jun; 18(11):4111-8. PubMed ID: 20451395
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Species-dependent differences in monoamine oxidase A and B-catalyzed oxidation of various C4 substituted 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridinyl derivatives.
    Inoue H; Castagnoli K; Van Der Schyf C; Mabic S; Igarashi K; Castagnoli N
    J Pharmacol Exp Ther; 1999 Nov; 291(2):856-64. PubMed ID: 10525109
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Assessment of structural requirements for the monoamine oxidase-B-catalyzed oxidation of 1,4-disubstituted-1,2,3,6-tetrahydropyridine derivatives related to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Mabic S; Castagnoli N
    J Med Chem; 1996 Sep; 39(19):3694-700. PubMed ID: 8809158
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The tert-butoxyl radical mediated hydrogen atom transfer reactions of the Parkinsonian proneurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and selected tertiary amines.
    Suleman NK; Flores J; Tanko JM; Isin EM; Castagnoli N
    Bioorg Med Chem; 2008 Sep; 16(18):8557-62. PubMed ID: 18713667
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deuterium isotope effect studies on the MAO-B catalyzed oxidation of 4-benzyl-1-cyclopropyl-1,2,3,6-tetrahydropyridine.
    Anderson AH; Kuttab S; Castagnoli N
    Biochemistry; 1996 Mar; 35(10):3335-40. PubMed ID: 8605171
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationships in the inhibition of monoamine oxidase B by 1-methyl-3-phenylpyrroles.
    Ogunrombi MO; Malan SF; Terre'blanche G; Castagnoli N; Bergh JJ; Petzer JP
    Bioorg Med Chem; 2008 Mar; 16(5):2463-72. PubMed ID: 18065227
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deuterium isotope effect measurements on the interactions of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidase B.
    Ottoboni S; Caldera P; Trevor A; Castagnoli N
    J Biol Chem; 1989 Aug; 264(23):13684-8. PubMed ID: 2788162
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).
    Herraiz T; Arán VJ; Guillén H
    Free Radic Res; 2009 Oct; 43(10):975-84. PubMed ID: 19669997
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6.
    Herraiz T; Guillén H; Arán VJ; Idle JR; Gonzalez FJ
    Toxicol Appl Pharmacol; 2006 Nov; 216(3):387-98. PubMed ID: 16870220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs.
    Youngster SK; Sonsalla PK; Sieber BA; Heikkila RE
    J Pharmacol Exp Ther; 1989 Jun; 249(3):820-8. PubMed ID: 2786564
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Studies on the monoamine oxidase-B-catalyzed biotransformation of 4-azaaryl-1-methyl-1,2,3,6-tetrahydropyridine derivatives.
    Nimkar SK; Mabic S; Anderson AH; Palmer SL; Graham TH; de Jonge M; Hazelwood L; Hislop SJ; Castagnoli N
    J Med Chem; 1999 May; 42(10):1828-35. PubMed ID: 10346935
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The behaviour of aryl pyrrolines with monoamine oxidase.
    Williams CH; Lawson J
    Neurobiology (Bp); 1999; 7(2):225-33. PubMed ID: 10591055
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and monoamine oxidase B catalyzed oxidation of C-4 heteroaromatic substituted 1,2,3,6-tetrahydropyridine derivatives.
    Nimkar SK; Anderson AH; Rimoldi JM; Stanton M; Castagnoli KP; Mabic S; Wang YX; Castagnoli N
    Chem Res Toxicol; 1996 Sep; 9(6):1013-22. PubMed ID: 8870990
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Studies on the mechanism of MPTP oxidation by human liver monoamine oxidase B.
    Gessner W; Brossi A; Bembenek ME; Fritz RR; Abell CW
    FEBS Lett; 1986 Apr; 199(1):100-2. PubMed ID: 3485542
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Depletion of heart norepinephrine in mice by some analogs of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).
    Fuller RW; Hemrick-Luecke SK
    Res Commun Chem Pathol Pharmacol; 1987 May; 56(2):147-56. PubMed ID: 3496637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.
    Herraiz T; Guillén H
    Food Chem Toxicol; 2011 Aug; 49(8):1773-81. PubMed ID: 21554916
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Catalytic biotransformation of physiologically active 1-methyl-4- aryl-1,2,3,6-tetrahydropyridines under the action of monoaminooxidase].
    Bachurin SO; Sablin SO; Grishina GV; Gaĭdarova EL; Dubova DG
    Bioorg Khim; 1989 May; 15(5):620-6. PubMed ID: 2788421
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies.
    Harik SI; Riachi NJ; Hritz MA; Berridge MS; Sayre LM
    J Pharmacol Exp Ther; 1993 Aug; 266(2):790-5. PubMed ID: 8355208
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.