These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

349 related articles for article (PubMed ID: 18799803)

  • 1. 2-Diethylaminoethyl-2,2-diphenylvalerate-HCl (SKF525A) revisited: comparative cytochrome P450 inhibition in human liver microsomes by SKF525A, its metabolites, and SKF-acid and SKF-alcohol.
    Franklin MR; Hathaway LB
    Drug Metab Dispos; 2008 Dec; 36(12):2539-46. PubMed ID: 18799803
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes.
    Guo Z; Raeissi S; White RB; Stevens JC
    Drug Metab Dispos; 1997 Mar; 25(3):390-3. PubMed ID: 9172960
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the selectivity and mechanism of cytochrome P450 inhibition by dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate.
    Kim JY; Baek M; Lee S; Kim SO; Dong MS; Kim BR; Kim DH
    Drug Metab Dispos; 2001 Dec; 29(12):1555-60. PubMed ID: 11717174
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s.
    Prueksaritanont T; Gorham LM; Ma B; Liu L; Yu X; Zhao JJ; Slaughter DE; Arison BH; Vyas KP
    Drug Metab Dispos; 1997 Oct; 25(10):1191-9. PubMed ID: 9321523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations.
    Filppula AM; Laitila J; Neuvonen PJ; Backman JT
    Drug Metab Dispos; 2011 May; 39(5):904-11. PubMed ID: 21289076
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes.
    Ono S; Hatanaka T; Hotta H; Satoh T; Gonzalez FJ; Tsutsui M
    Xenobiotica; 1996 Jul; 26(7):681-93. PubMed ID: 8819299
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions.
    Fischer V; Johanson L; Heitz F; Tullman R; Graham E; Baldeck JP; Robinson WT
    Drug Metab Dispos; 1999 Mar; 27(3):410-6. PubMed ID: 10064574
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced rates of cytochrome P450 metabolic-intermediate complex formation from nonmacrolide amines in rifampicin-treated rabbit liver microsomes.
    Franklin MR
    Drug Metab Dispos; 1995 Dec; 23(12):1379-82. PubMed ID: 8689947
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Denitrosation of the anti-cancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea catalyzed by microsomal glutathione S-transferase and cytochrome P450 monooxygenases.
    Weber GF; Waxman DJ
    Arch Biochem Biophys; 1993 Dec; 307(2):369-78. PubMed ID: 8274024
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB) by human liver microsomes: characterization of metabolic pathways and of cytochrome P450 isoforms involved.
    Baek MS; Kim JY; Myung SW; Yim YH; Jeong JH; Kim DH
    Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):381-8. PubMed ID: 11259320
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitory effect of glyburide on human cytochrome p450 isoforms in human liver microsomes.
    Kim KA; Park JY
    Drug Metab Dispos; 2003 Sep; 31(9):1090-2. PubMed ID: 12920163
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide.
    Pekthong D; Martin H; Abadie C; Bonet A; Heyd B; Mantion G; Richert L
    J Ethnopharmacol; 2008 Feb; 115(3):432-40. PubMed ID: 18053665
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of vanoxerine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, by human cytochrome P450 enzymes.
    Cherstniakova SA; Bi D; Fuller DR; Mojsiak JZ; Collins JM; Cantilena LR
    Drug Metab Dispos; 2001 Sep; 29(9):1216-20. PubMed ID: 11502731
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation.
    Stresser DM; Kupfer D
    Drug Metab Dispos; 1998 Sep; 26(9):868-74. PubMed ID: 9733665
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components.
    Chatterjee P; Franklin MR
    Drug Metab Dispos; 2003 Nov; 31(11):1391-7. PubMed ID: 14570772
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine (N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes.
    Bae SK; Cao S; Seo KA; Kim H; Kim MJ; Shon JH; Liu KH; Zhou HH; Shin JG
    Drug Metab Dispos; 2008 Aug; 36(8):1679-88. PubMed ID: 18474675
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
    Prakash C; Wang W; O'Connell T; Johnson KA
    Drug Metab Dispos; 2008 Oct; 36(10):2093-103. PubMed ID: 18653741
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids.
    Knickle LC; Bend JR
    Mol Pharmacol; 1994 Jun; 45(6):1273-80. PubMed ID: 8022420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of sinomenine on human cytochrome P450 activity.
    Yao YM; Cao W; Cao YJ; Cheng ZN; Ou-Yang DS; Liu ZQ; Zhou HH
    Clin Chim Acta; 2007 Apr; 379(1-2):113-8. PubMed ID: 17292874
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Catalyzation of cocaine N-demethylation by cytochromes P4502B, P4503A, and P4502D in fish liver.
    Arinç E; Bozcaarmutlu A
    J Biochem Mol Toxicol; 2003; 17(3):169-76. PubMed ID: 12815613
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.