452 related articles for article (PubMed ID: 18799805)
1. A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.
Ma X; Cheung C; Krausz KW; Shah YM; Wang T; Idle JR; Gonzalez FJ
Drug Metab Dispos; 2008 Dec; 36(12):2506-12. PubMed ID: 18799805
[TBL] [Abstract][Full Text] [Related]
2. CYP3A4 Induction in the Liver and Intestine of Pregnane X Receptor/CYP3A-Humanized Mice: Approaches by Mass Spectrometry Imaging and Portal Blood Analysis.
Kobayashi K; Kuze J; Abe S; Takehara S; Minegishi G; Igarashi K; Kitajima S; Kanno J; Yamamoto T; Oshimura M; Kazuki Y
Mol Pharmacol; 2019 Nov; 96(5):600-608. PubMed ID: 31455676
[TBL] [Abstract][Full Text] [Related]
3. Rifampicin-activated human pregnane X receptor and CYP3A4 induction enhance acetaminophen-induced toxicity.
Cheng J; Ma X; Krausz KW; Idle JR; Gonzalez FJ
Drug Metab Dispos; 2009 Aug; 37(8):1611-21. PubMed ID: 19460945
[TBL] [Abstract][Full Text] [Related]
4. 3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition.
Antolino-Lobo I; Meulenbelt J; Nijmeijer SM; Maas-Bakker RF; Meijerman I; van den Berg M; van Duursen MB
Toxicol Lett; 2011 May; 203(1):82-91. PubMed ID: 21402137
[TBL] [Abstract][Full Text] [Related]
5. CYP3A4 and pregnane X receptor humanized mice.
Gonzalez FJ
J Biochem Mol Toxicol; 2007; 21(4):158-62. PubMed ID: 17936928
[TBL] [Abstract][Full Text] [Related]
6. Resveratrol suppresses the inducible expression of CYP3A4 through the pregnane X receptor.
Deng R; Xu C; Chen X; Chen P; Wang Y; Zhou X; Jin J; Niu L; Ying M; Huang M; Bi H
J Pharmacol Sci; 2014; 126(2):146-54. PubMed ID: 25341566
[TBL] [Abstract][Full Text] [Related]
7. Metabolism of amprenavir in liver microsomes: role of CYP3A4 inhibition for drug interactions.
Decker CJ; Laitinen LM; Bridson GW; Raybuck SA; Tung RD; Chaturvedi PR
J Pharm Sci; 1998 Jul; 87(7):803-7. PubMed ID: 9649346
[TBL] [Abstract][Full Text] [Related]
8. The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A.
Ma X; Shah Y; Cheung C; Guo GL; Feigenbaum L; Krausz KW; Idle JR; Gonzalez FJ
Drug Metab Dispos; 2007 Feb; 35(2):194-200. PubMed ID: 17093002
[TBL] [Abstract][Full Text] [Related]
9. PXR/CYP3A4-humanized mice for studying drug-drug interactions involving intestinal P-glycoprotein.
Holmstock N; Gonzalez FJ; Baes M; Annaert P; Augustijns P
Mol Pharm; 2013 Mar; 10(3):1056-62. PubMed ID: 23360470
[TBL] [Abstract][Full Text] [Related]
10. Establishment of a stable human cell line, HPL-A3, for use in reporter gene assays of cytochrome P450 3A inducers.
Sekimoto M; Sano S; Hosaka T; Nemoto K; Degawa M
Biol Pharm Bull; 2012; 35(5):677-85. PubMed ID: 22687401
[TBL] [Abstract][Full Text] [Related]
11. Mg2+/Mn2+-dependent phosphatase 1A is involved in regulating pregnane X receptor-mediated cytochrome p450 3A4 gene expression.
Pondugula SR; Flannery PC; Apte U; Babu JR; Geetha T; Rege SD; Chen T; Abbott KL
Drug Metab Dispos; 2015 Mar; 43(3):385-91. PubMed ID: 25561723
[TBL] [Abstract][Full Text] [Related]
12. Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1.
Wang YM; Lin W; Chai SC; Wu J; Ong SS; Schuetz EG; Chen T
Toxicol Appl Pharmacol; 2013 Oct; 272(1):96-107. PubMed ID: 23707768
[TBL] [Abstract][Full Text] [Related]
13. Pregnane X receptor- and CYP3A4-humanized mouse models and their applications.
Cheng J; Ma X; Gonzalez FJ
Br J Pharmacol; 2011 Jun; 163(3):461-8. PubMed ID: 21091656
[TBL] [Abstract][Full Text] [Related]
14. Human pregnane X receptor agonism by Ginkgo biloba extract: assessment of the role of individual ginkgolides.
Lau AJ; Yang G; Rajaraman G; Baucom CC; Chang TK
J Pharmacol Exp Ther; 2010 Dec; 335(3):771-80. PubMed ID: 20739453
[TBL] [Abstract][Full Text] [Related]
15. Assessment of human pregnane X receptor involvement in pesticide-mediated activation of CYP3A4 gene.
Matsubara T; Noracharttiyapot W; Toriyabe T; Yoshinari K; Nagata K; Yamazoe Y
Drug Metab Dispos; 2007 May; 35(5):728-33. PubMed ID: 17293382
[TBL] [Abstract][Full Text] [Related]
16. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
17. Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.
Svecova L; Vrzal R; Burysek L; Anzenbacherova E; Cerveny L; Grim J; Trejtnar F; Kunes J; Pour M; Staud F; Anzenbacher P; Dvorak Z; Pavek P
Drug Metab Dispos; 2008 Feb; 36(2):339-48. PubMed ID: 17998298
[TBL] [Abstract][Full Text] [Related]
18. Rifaximin is a gut-specific human pregnane X receptor activator.
Ma X; Shah YM; Guo GL; Wang T; Krausz KW; Idle JR; Gonzalez FJ
J Pharmacol Exp Ther; 2007 Jul; 322(1):391-8. PubMed ID: 17442842
[TBL] [Abstract][Full Text] [Related]
19. Investigation of drug-drug interactions caused by human pregnane X receptor-mediated induction of CYP3A4 and CYP2C subfamilies in chimeric mice with a humanized liver.
Hasegawa M; Tahara H; Inoue R; Kakuni M; Tateno C; Ushiki J
Drug Metab Dispos; 2012 Mar; 40(3):474-80. PubMed ID: 22126990
[TBL] [Abstract][Full Text] [Related]
20. Up-regulating CYP3A4 expression in C3A cells by transfection with a novel chimeric regulator of hPXR-p53-AD.
Chen F; Rao XH; Yang JL; Pan MX; Gao Y; Li ZL; Li Y; Zhu YF; Wang Y
PLoS One; 2014; 9(5):e95752. PubMed ID: 24788541
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
