BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 18800761)

  • 1. Melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 modified at the para position of the benzyl side chain (DPhe): importance for mouse melanocortin-3 receptor agonist versus antagonist activity.
    Proneth B; Pogozheva ID; Portillo FP; Mosberg HI; Haskell-Luevano C
    J Med Chem; 2008 Sep; 51(18):5585-93. PubMed ID: 18800761
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors: part 2 modifications at the Phe position.
    Holder JR; Bauzo RM; Xiang Z; Haskell-Luevano C
    J Med Chem; 2002 Jul; 45(14):3073-81. PubMed ID: 12086493
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors. 1. Modifications at the His position.
    Holder JR; Bauzo RM; Xiang Z; Haskell-Luevano C
    J Med Chem; 2002 Jun; 45(13):2801-10. PubMed ID: 12061882
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships of the unique and potent agouti-related protein (AGRP)-melanocortin chimeric Tyr-c[beta-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 peptide template.
    Wilczynski A; Wilson KR; Scott JW; Edison AS; Haskell-Luevano C
    J Med Chem; 2005 Apr; 48(8):3060-75. PubMed ID: 15828845
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure⁻Activity Relationships of the Tetrapeptide Ac-His-Arg-(
    Schlasner KN; Ericson MD; Doering SR; Freeman KT; Weinrich M; Haskell-Luevano C
    Molecules; 2019 Apr; 24(8):. PubMed ID: 31013889
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of a Pan-Melanocortin Receptor Antagonist [Ac-DPhe(pI)-Arg-Nal(2')-Orn-NH
    Ericson MD; Tran LT; Mathre SS; Freeman KT; Holdaway K; John K; Lunzer MM; Bouchard JL; Haskell-Luevano C
    J Med Chem; 2023 Jun; 66(12):8103-8117. PubMed ID: 37307241
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa
    Doering SR; Freeman KT; Schnell SM; Haslach EM; Dirain M; Debevec G; Geer P; Santos RG; Giulianotti MA; Pinilla C; Appel JR; Speth RC; Houghten RA; Haskell-Luevano C
    J Med Chem; 2017 May; 60(10):4342-4357. PubMed ID: 28453292
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the mouse melanocortin receptors. Part 3: modifications at the Arg position.
    Holder JR; Xiang Z; Bauzo RM; Haskell-Luevano C
    Peptides; 2003 Jan; 24(1):73-82. PubMed ID: 12576087
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-D-Phe-Arg-Trp-NH2 at the mouse melanocortin receptors. 4. Modifications at the Trp position.
    Holder JR; Xiang Z; Bauzo RM; Haskell-Luevano C
    J Med Chem; 2002 Dec; 45(26):5736-44. PubMed ID: 12477357
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
    J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-terminal fatty acylated His-dPhe-Arg-Trp-NH(2) tetrapeptides: influence of fatty acid chain length on potency and selectivity at the mouse melanocortin receptors and human melanocytes.
    Todorovic A; Holder JR; Bauzo RM; Scott JW; Kavanagh R; Abdel-Malek Z; Haskell-Luevano C
    J Med Chem; 2005 May; 48(9):3328-36. PubMed ID: 15857138
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and Pharmacology of α/β(3)-Peptides Based on the Melanocortin Agonist Ac-His-dPhe-Arg-Trp-NH2 Sequence.
    Singh A; Tala SR; Flores V; Freeman K; Haskell-Luevano C
    ACS Med Chem Lett; 2015 May; 6(5):568-72. PubMed ID: 26005535
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH
    Lensing CJ; Adank DN; Wilber SL; Freeman KT; Schnell SM; Speth RC; Zarth AT; Haskell-Luevano C
    ACS Chem Neurosci; 2017 Jun; 8(6):1262-1278. PubMed ID: 28128928
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist versus a μM MC4R Partial Agonist.
    Fleming KA; Freeman KT; Powers MD; Santos RG; Debevec G; Giulianotti MA; Houghten RA; Doering SR; Pinilla C; Haskell-Luevano C
    J Med Chem; 2019 Mar; 62(5):2738-2749. PubMed ID: 30741545
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiresidue Tetrapeptide Substitutions Yield a 140-fold Selective Melanocortin-3 over Melanocortin-4 Receptor Agonist.
    Ericson MD; Shaikh R; Larson CM; Freeman KT; Haskell-Luevano C
    ACS Med Chem Lett; 2021 Jan; 12(1):115-120. PubMed ID: 33488972
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chimeric NDP-MSH and MTII melanocortin peptides with agouti-related protein (AGRP) Arg-Phe-Phe amino acids possess agonist melanocortin receptor activity.
    Joseph CG; Wilczynski A; Holder JR; Xiang Z; Bauzo RM; Scott JW; Haskell-Luevano C
    Peptides; 2003 Dec; 24(12):1899-908. PubMed ID: 15127941
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of melanocortin NDP-MSH agonist peptide fragments at the mouse central and peripheral melanocortin receptors.
    Haskell-Luevano C; Holder JR; Monck EK; Bauzo RM
    J Med Chem; 2001 Jun; 44(13):2247-52. PubMed ID: 11405661
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ac-Trp-DPhe(p-I)-Arg-Trp-NH2, a 250-Fold Selective Melanocortin-4 Receptor (MC4R) Antagonist over the Melanocortin-3 Receptor (MC3R), Affects Energy Homeostasis in Male and Female Mice Differently.
    Lensing CJ; Adank DN; Doering SR; Wilber SL; Andreasen A; Schaub JW; Xiang Z; Haskell-Luevano C
    ACS Chem Neurosci; 2016 Sep; 7(9):1283-91. PubMed ID: 27385405
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modified melanocortin tetrapeptide Ac-His-dPhe-Arg-Trp-NH at the arginine side chain with ureas and thioureas.
    Joseph CG; Sorensen NB; Wood MS; Xiang Z; Moore MC; Haskell-Luevano C
    J Pept Res; 2005 Nov; 66(5):297-307. PubMed ID: 16218996
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Melanocortin antagonist tetrapeptides with minimal agonist activity at the mouse melanocortin-3 receptor.
    Doering SR; Todorovic A; Haskell-Luevano C
    ACS Med Chem Lett; 2015 Feb; 6(2):123-7. PubMed ID: 25699138
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.