508 related articles for article (PubMed ID: 18805405)
1. PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA.
Yu C; Ye S; Sun H; Liu Y; Gao L; Shen C; Chen S; Zeng S
Chem Biol Interact; 2009 Jan; 177(1):58-64. PubMed ID: 18805405
[TBL] [Abstract][Full Text] [Related]
2. Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study.
Liu YH; Mo SL; Bi HC; Hu BF; Li CG; Wang YT; Huang L; Huang M; Duan W; Liu JP; Wei MQ; Zhou SF
Xenobiotica; 2011 Apr; 41(4):259-80. PubMed ID: 21117944
[TBL] [Abstract][Full Text] [Related]
3. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
4. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
[TBL] [Abstract][Full Text] [Related]
5. Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes.
Qiu F; Zhang R; Wang G; Gao C; Sun J; Jiang J; Ma Y
Xenobiotica; 2010 Dec; 40(12):800-6. PubMed ID: 20964620
[TBL] [Abstract][Full Text] [Related]
6. Tanshinone IIA ameliorates dextran sulfate sodium-induced inflammatory bowel disease via the pregnane X receptor.
Zhang X; Wang Y; Ma Z; Liang Q; Tang X; Hu D; Tan H; Xiao C; Gao Y
Drug Des Devel Ther; 2015; 9():6343-62. PubMed ID: 26674743
[TBL] [Abstract][Full Text] [Related]
7. Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells.
Sane RS; Buckley DJ; Buckley AR; Nallani SC; Desai PB
Drug Metab Dispos; 2008 May; 36(5):946-54. PubMed ID: 18299335
[TBL] [Abstract][Full Text] [Related]
8. Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor.
Moscovitz JE; Lin Z; Johnson N; Tu M; Goosen TC; Weng Y; Kalgutkar AS
Xenobiotica; 2018 Jul; 48(7):647-655. PubMed ID: 28685622
[TBL] [Abstract][Full Text] [Related]
9. [Screening active components in compound danshen based on PXR-CYP3A4: an experimental study].
Xiao Y; Ma ZC; Wang YG; Tan HL; Liu HS; Zhang XX; Lu BB; Tang XL; Linag QD; Xiao CR
Zhongguo Zhong Xi Yi Jie He Za Zhi; 2014 May; 34(5):606-10. PubMed ID: 24941853
[TBL] [Abstract][Full Text] [Related]
10. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
[TBL] [Abstract][Full Text] [Related]
11. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
El-Sankary W; Bombail V; Gibson GG; Plant N
Drug Metab Dispos; 2002 Sep; 30(9):1029-34. PubMed ID: 12167569
[TBL] [Abstract][Full Text] [Related]
12. In vitro inhibitory effects of ethanol extract of Danshen (Salvia miltiorrhiza) and its components on the catalytic activity of soluble epoxide hydrolase.
Xu M; Hao H; Jiang L; Long F; Wei Y; Ji H; Sun B; Peng Y; Wang G; Ju W; Li P
Phytomedicine; 2015 Apr; 22(4):444-51. PubMed ID: 25925966
[TBL] [Abstract][Full Text] [Related]
13. Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn.
Huang L; Huang M; Li YH; Li RM; Zeng Y; Kuang SY; Zhang L; Wang YT; Bi HC
J Ethnopharmacol; 2013 Jul; 148(2):596-602. PubMed ID: 23702042
[TBL] [Abstract][Full Text] [Related]
14. Tanshinone IIA exerts protective effects in a LCA-induced cholestatic liver model associated with participation of pregnane X receptor.
Zhang X; Ma Z; Liang Q; Tang X; Hu D; Liu C; Tan H; Xiao C; Zhang B; Wang Y; Gao Y
J Ethnopharmacol; 2015 Apr; 164():357-67. PubMed ID: 25660334
[TBL] [Abstract][Full Text] [Related]
15. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Gupta A; Mugundu GM; Desai PB; Thummel KE; Unadkat JD
Drug Metab Dispos; 2008 Jun; 36(6):1172-80. PubMed ID: 18332086
[TBL] [Abstract][Full Text] [Related]
16. Proapoptotic and TRAIL-sensitizing constituents isolated from Salvia militiorrhiza (Danshen).
Chang CC; Lai JS; Tsai CS; Ma SW; Lin JY; Huang LR; Lu CH; Liao EC; Ho TF
J Biosci Bioeng; 2013 Oct; 116(4):516-23. PubMed ID: 23660075
[TBL] [Abstract][Full Text] [Related]
17. Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.
Li Y; Wang Q; Yao X; Li Y
Eur J Pharmacol; 2010 Aug; 640(1-3):46-54. PubMed ID: 20580705
[TBL] [Abstract][Full Text] [Related]
18. Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation.
Lee WY; Chiu LC; Yeung JH
Food Chem Toxicol; 2008 Jan; 46(1):328-38. PubMed ID: 17892911
[TBL] [Abstract][Full Text] [Related]
19. Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.
Takezawa T; Matsunaga T; Aikawa K; Nakamura K; Ohmori S
Drug Metab Pharmacokinet; 2012; 27(4):430-8. PubMed ID: 22333269
[TBL] [Abstract][Full Text] [Related]
20. CAR-mediated up-regulation of CYP3A4 expression in LS174T cells by Chinese herbal compounds.
Huang L; Bi HC; Liu YH; Wang YT; Xue XP; Huang M
Drug Metab Pharmacokinet; 2011; 26(4):331-40. PubMed ID: 21422673
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
