165 related articles for article (PubMed ID: 18809221)
61. Leflunomide attenuates hepatocyte injury by inhibiting Kupffer cells.
Yao HW; Li J; Chen JQ; Xu SY
World J Gastroenterol; 2004 Jun; 10(11):1608-11. PubMed ID: 15162534
[TBL] [Abstract][Full Text] [Related]
62. In vivo lymphoproliferation in the popliteal lymph node (PLN) assay can be inhibited by leflunomide's active metabolite A77 1726.
Schorlemmer HU; Kurrle R; Schleyerbach R; Bartlett RR
Inflamm Res; 1999 Dec; 48 Suppl 2():S111-2. PubMed ID: 10667839
[No Abstract] [Full Text] [Related]
63. A771726, the active metabolite of leflunomide, directly inhibits the activity of cyclo-oxygenase-2 in vitro and in vivo in a substrate-sensitive manner.
Hamilton LC; Vojnovic I; Warner TD
Br J Pharmacol; 1999 Aug; 127(7):1589-96. PubMed ID: 10455314
[TBL] [Abstract][Full Text] [Related]
64. Involvement of endoplasmic reticulum in glycochenodeoxycholic acid-induced apoptosis in rat hepatocytes.
Tsuchiya S; Tsuji M; Morio Y; Oguchi K
Toxicol Lett; 2006 Oct; 166(2):140-9. PubMed ID: 16860497
[TBL] [Abstract][Full Text] [Related]
65. Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-kappaB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents apoptosis.
Schoemaker MH; Ros JE; Homan M; Trautwein C; Liston P; Poelstra K; van Goor H; Jansen PL; Moshage H
J Hepatol; 2002 Jun; 36(6):742-50. PubMed ID: 12044523
[TBL] [Abstract][Full Text] [Related]
66. Inhibition of porcine epidemic diarrhea virus (PEDV) replication by A77 1726 through targeting JAK and Src tyrosine kinases.
Li X; Sun J; Prinz RA; Liu X; Xu X
Virology; 2020 Dec; 551():75-83. PubMed ID: 32829915
[TBL] [Abstract][Full Text] [Related]
67. Inhibition of canine distemper virus replication by blocking pyrimidine nucleotide synthesis with A77 1726, the active metabolite of the anti-inflammatory drug leflunomide.
Li Y; Yi L; Cheng S; Wang Y; Wang J; Sun J; Zhang Q; Xu X
J Gen Virol; 2021 Mar; 102(3):. PubMed ID: 33416466
[TBL] [Abstract][Full Text] [Related]
68. Sex hormones modulate the effects of Leflunomide on cytokine production by cultures of differentiated monocyte/macrophages and synovial macrophages from rheumatoid arthritis patients.
Cutolo M; Montagna P; Brizzolara R; Sulli A; Seriolo B; Villaggio B; Triolo P; Clerico P; Soldano S
J Autoimmun; 2009; 32(3-4):254-60. PubMed ID: 19324522
[TBL] [Abstract][Full Text] [Related]
69. Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation.
Xu X; Sun J; Song R; Doscas ME; Williamson AJ; Zhou J; Sun J; Jiao X; Liu X; Li Y
Oncotarget; 2017 May; 8(18):30438-30454. PubMed ID: 28389629
[TBL] [Abstract][Full Text] [Related]
70. Neurotropin suppresses inflammatory cytokine expression and cell death through suppression of NF-κB and JNK in hepatocytes.
Zhang B; Roh YS; Liang S; Liu C; Naiki M; Masuda K; Seki E
PLoS One; 2014; 9(12):e114071. PubMed ID: 25470242
[TBL] [Abstract][Full Text] [Related]
71. Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes.
Webster CR; Anwer MS
Hepatology; 1998 May; 27(5):1324-31. PubMed ID: 9581687
[TBL] [Abstract][Full Text] [Related]
72. Roles of reactive oxygen species, NF-kappaB, and peroxiredoxins in glycochenodeoxycholic acid-induced rat hepatocytes death.
Chu SH; Lee-Kang J; Lee KH; Lee K
Pharmacology; 2003 Sep; 69(1):12-9. PubMed ID: 12886025
[TBL] [Abstract][Full Text] [Related]
73. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
Qiao L; Studer E; Leach K; McKinstry R; Gupta S; Decker R; Kukreja R; Valerie K; Nagarkatti P; El Deiry W; Molkentin J; Schmidt-Ullrich R; Fisher PB; Grant S; Hylemon PB; Dent P
Mol Biol Cell; 2001 Sep; 12(9):2629-45. PubMed ID: 11553704
[TBL] [Abstract][Full Text] [Related]
74. Beta-carotene prevents bile acid-induced cytotoxicity in the rat hepatocyte: Evidence for an antioxidant and anti-apoptotic role of beta-carotene in vitro.
Gumpricht E; Dahl R; Devereaux MW; Sokol RJ
Pediatr Res; 2004 May; 55(5):814-21. PubMed ID: 14764912
[TBL] [Abstract][Full Text] [Related]
75. Suppressive effect of leflunomide on rat hepatic stellate cell proliferation involves on PDGF-BB-elicited activation of three mitogen-activated protein kinases.
Si HF; Lv X; Guo A; Jiang H; Li J
Cytokine; 2008 Apr; 42(1):24-31. PubMed ID: 18343153
[TBL] [Abstract][Full Text] [Related]
76. Tauroursodeoxycholate Protects Rat Hepatocytes from Bile Acid-Induced Apoptosis via β1-Integrin- and Protein Kinase A-Dependent Mechanisms.
Sommerfeld A; Reinehr R; Häussinger D
Cell Physiol Biochem; 2015; 36(3):866-83. PubMed ID: 26044599
[TBL] [Abstract][Full Text] [Related]
77. Identification and characterization of potential new therapeutic targets in inflammatory and autoimmune diseases.
Mangold U; Dax CI; Saar K; Schwab W; Kirschbaum B; Müllner S
Eur J Biochem; 1999 Dec; 266(3):1184-91. PubMed ID: 10583416
[TBL] [Abstract][Full Text] [Related]
78. Honokiol reduces oxidative stress, c-jun-NH2-terminal kinase phosphorylation and protects against glycochenodeoxycholic acid-induced apoptosis in primary cultured rat hepatocytes.
Park EJ; Kim SY; Zhao YZ; Sohn DH
Planta Med; 2006 Jun; 72(7):661-4. PubMed ID: 16732532
[TBL] [Abstract][Full Text] [Related]
79. Purification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide.
Bruneau JM; Yea CM; Spinella-Jaegle S; Fudali C; Woodward K; Robson PA; Sautès C; Westwood R; Kuo EA; Williamson RA; Ruuth E
Biochem J; 1998 Dec; 336 ( Pt 2)(Pt 2):299-303. PubMed ID: 9820804
[TBL] [Abstract][Full Text] [Related]
80. Inhibition of taurolithocholate 3-sulfate-induced apoptosis by cyclic AMP in rat hepatocytes involves protein kinase A-dependent and -independent mechanisms.
Graf D; Reinehr R; Kurz AK; Fischer R; Häussinger D
Arch Biochem Biophys; 2003 Jul; 415(1):34-42. PubMed ID: 12801510
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
