148 related articles for article (PubMed ID: 18809619)
1. Translational bypass of nonsense mutations in zebrafish rep1, pax2.1 and lamb1 highlights a viable therapeutic option for untreatable genetic eye disease.
Moosajee M; Gregory-Evans K; Ellis CD; Seabra MC; Gregory-Evans CY
Hum Mol Genet; 2008 Dec; 17(24):3987-4000. PubMed ID: 18809619
[TBL] [Abstract][Full Text] [Related]
2. Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma.
Gregory-Evans CY; Moosajee M; Shan X; Gregory-Evans K
Mol Vis; 2011; 17():1473-84. PubMed ID: 21677791
[TBL] [Abstract][Full Text] [Related]
3. Functional rescue of REP1 following treatment with PTC124 and novel derivative PTC-414 in human choroideremia fibroblasts and the nonsense-mediated zebrafish model.
Moosajee M; Tracey-White D; Smart M; Weetall M; Torriano S; Kalatzis V; da Cruz L; Coffey P; Webster AR; Welch E
Hum Mol Genet; 2016 Aug; 25(16):3416-3431. PubMed ID: 27329764
[TBL] [Abstract][Full Text] [Related]
4. Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development.
Viringipurampeer IA; Ferreira T; DeMaria S; Yoon JJ; Shan X; Moosajee M; Gregory-Evans K; Ngai J; Gregory-Evans CY
Hum Mol Genet; 2012 May; 21(10):2357-69. PubMed ID: 22357656
[TBL] [Abstract][Full Text] [Related]
5. Regional Gene Expression Profile Comparison Reveals the Unique Transcriptome of the Optic Fissure.
Cao M; Ouyang J; Liang H; Guo J; Lin S; Yang S; Xie T; Chen S
Invest Ophthalmol Vis Sci; 2018 Dec; 59(15):5773-5784. PubMed ID: 30521666
[TBL] [Abstract][Full Text] [Related]
6. Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations.
Nudelman I; Rebibo-Sabbah A; Cherniavsky M; Belakhov V; Hainrichson M; Chen F; Schacht J; Pilch DS; Ben-Yosef T; Baasov T
J Med Chem; 2009 May; 52(9):2836-45. PubMed ID: 19309154
[TBL] [Abstract][Full Text] [Related]
7. Pax2a, but not pax2b, influences cell survival and periocular mesenchyme localization to facilitate zebrafish optic fissure closure.
Lusk S; Kwan KM
Dev Dyn; 2022 Apr; 251(4):625-644. PubMed ID: 34535934
[TBL] [Abstract][Full Text] [Related]
8. Single choroideremia gene in nonmammalian vertebrates explains early embryonic lethality of the zebrafish model of choroideremia.
Moosajee M; Tulloch M; Baron RA; Gregory-Evans CY; Pereira-Leal JB; Seabra MC
Invest Ophthalmol Vis Sci; 2009 Jun; 50(6):3009-16. PubMed ID: 19117920
[TBL] [Abstract][Full Text] [Related]
9. The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.
Friesen WJ; Johnson B; Sierra J; Zhuo J; Vazirani P; Xue X; Tomizawa Y; Baiazitov R; Morrill C; Ren H; Babu S; Moon YC; Branstrom A; Mollin A; Hedrick J; Sheedy J; Elfring G; Weetall M; Colacino JM; Welch EM; Peltz SW
PLoS One; 2018; 13(10):e0206158. PubMed ID: 30359426
[TBL] [Abstract][Full Text] [Related]
10. Gene selective suppression of nonsense termination using antisense agents.
Kulyté A; Dryselius R; Karlsson J; Good L
Biochim Biophys Acta; 2005 Sep; 1730(3):165-72. PubMed ID: 16135388
[TBL] [Abstract][Full Text] [Related]
11. Abnormal vasculature interferes with optic fissure closure in lmo2 mutant zebrafish embryos.
Weiss O; Kaufman R; Michaeli N; Inbal A
Dev Biol; 2012 Sep; 369(2):191-8. PubMed ID: 22819672
[TBL] [Abstract][Full Text] [Related]
12. Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure.
Brown JD; Dutta S; Bharti K; Bonner RF; Munson PJ; Dawid IB; Akhtar AL; Onojafe IF; Alur RP; Gross JM; Hejtmancik JF; Jiao X; Chan WY; Brooks BP
Proc Natl Acad Sci U S A; 2009 Feb; 106(5):1462-7. PubMed ID: 19171890
[TBL] [Abstract][Full Text] [Related]
13. Beneficial read-through of a USH1C nonsense mutation by designed aminoglycoside NB30 in the retina.
Goldmann T; Rebibo-Sabbah A; Overlack N; Nudelman I; Belakhov V; Baasov T; Ben-Yosef T; Wolfrum U; Nagel-Wolfrum K
Invest Ophthalmol Vis Sci; 2010 Dec; 51(12):6671-80. PubMed ID: 20671281
[TBL] [Abstract][Full Text] [Related]
14. Sox4 regulates choroid fissure closure by limiting Hedgehog signaling during ocular morphogenesis.
Wen W; Pillai-Kastoori L; Wilson SG; Morris AC
Dev Biol; 2015 Mar; 399(1):139-153. PubMed ID: 25557621
[TBL] [Abstract][Full Text] [Related]
15. The effect of gentamicin-induced readthrough on a novel premature termination codon of CD18 leukocyte adhesion deficiency patients.
Simon AJ; Lev A; Wolach B; Gavrieli R; Amariglio N; Rosenthal E; Gazit E; Eyal E; Rechavi G; Somech R
PLoS One; 2010 Nov; 5(11):e13659. PubMed ID: 21103413
[TBL] [Abstract][Full Text] [Related]
16. Impaired retinal differentiation and maintenance in zebrafish laminin mutants.
Biehlmaier O; Makhankov Y; Neuhauss SC
Invest Ophthalmol Vis Sci; 2007 Jun; 48(6):2887-94. PubMed ID: 17525225
[TBL] [Abstract][Full Text] [Related]
17. Hyaloid vasculature and mmp2 activity play a role during optic fissure fusion in zebrafish.
Weaver ML; Piedade WP; Meshram NN; Famulski JK
Sci Rep; 2020 Jun; 10(1):10136. PubMed ID: 32576859
[TBL] [Abstract][Full Text] [Related]
18. Drug-induced readthrough of premature stop codons leads to the stabilization of laminin alpha2 chain mRNA in CMD myotubes.
Allamand V; Bidou L; Arakawa M; Floquet C; Shiozuka M; Paturneau-Jouas M; Gartioux C; Butler-Browne GS; Mouly V; Rousset JP; Matsuda R; Ikeda D; Guicheney P
J Gene Med; 2008 Feb; 10(2):217-24. PubMed ID: 18074402
[TBL] [Abstract][Full Text] [Related]
19. Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells.
Knöll R; Postel R; Wang J; Krätzner R; Hennecke G; Vacaru AM; Vakeel P; Schubert C; Murthy K; Rana BK; Kube D; Knöll G; Schäfer K; Hayashi T; Holm T; Kimura A; Schork N; Toliat MR; Nürnberg P; Schultheiss HP; Schaper W; Schaper J; Bos E; Den Hertog J; van Eeden FJ; Peters PJ; Hasenfuss G; Chien KR; Bakkers J
Circulation; 2007 Jul; 116(5):515-25. PubMed ID: 17646580
[TBL] [Abstract][Full Text] [Related]
20. Translational read-through as an alternative approach for ocular gene therapy of retinal dystrophies caused by in-frame nonsense mutations.
Nagel-Wolfrum K; Möller F; Penner I; Wolfrum U
Vis Neurosci; 2014 Sep; 31(4-5):309-16. PubMed ID: 24912600
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
