173 related articles for article (PubMed ID: 18809676)
1. Biophysical characterization of the interaction between hepatic glucokinase and its regulatory protein: impact of physiological and pharmacological effectors.
Anderka O; Boyken J; Aschenbach U; Batzer A; Boscheinen O; Schmoll D
J Biol Chem; 2008 Nov; 283(46):31333-40. PubMed ID: 18809676
[TBL] [Abstract][Full Text] [Related]
2. Discovery of Small-Molecule Glucokinase Regulatory Protein Modulators That Restore Glucokinase Activity.
Chen K; Michelsen K; Kurzeja RJ; Han J; Vazir M; St Jean DJ; Hale C; Wahl RC
J Biomol Screen; 2014 Aug; 19(7):1014-23. PubMed ID: 24717911
[TBL] [Abstract][Full Text] [Related]
3. Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase.
Choi JM; Seo MH; Kyeong HH; Kim E; Kim HS
Proc Natl Acad Sci U S A; 2013 Jun; 110(25):10171-6. PubMed ID: 23733961
[TBL] [Abstract][Full Text] [Related]
4. An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.
Futamura M; Hosaka H; Kadotani A; Shimazaki H; Sasaki K; Ohyama S; Nishimura T; Eiki J; Nagata Y
J Biol Chem; 2006 Dec; 281(49):37668-74. PubMed ID: 17028192
[TBL] [Abstract][Full Text] [Related]
5. Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence.
Zelent B; Raimondo A; Barrett A; Buettger CW; Chen P; Gloyn AL; Matschinsky FM
Biochem J; 2014 May; 459(3):551-64. PubMed ID: 24568320
[TBL] [Abstract][Full Text] [Related]
6. Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.
Farrelly D; Brown KS; Tieman A; Ren J; Lira SA; Hagan D; Gregg R; Mookhtiar KA; Hariharan N
Proc Natl Acad Sci U S A; 1999 Dec; 96(25):14511-6. PubMed ID: 10588736
[TBL] [Abstract][Full Text] [Related]
7. Modulation of glucokinase by glucose, small-molecule activator and glucokinase regulatory protein: steady-state kinetic and cell-based analysis.
Bourbonais FJ; Chen J; Huang C; Zhang Y; Pfefferkorn JA; Landro JA
Biochem J; 2012 Feb; 441(3):881-7. PubMed ID: 22044397
[TBL] [Abstract][Full Text] [Related]
8. Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity.
Park JM; Kim TH; Jo SH; Kim MY; Ahn YH
Sci Rep; 2015 Dec; 5():17395. PubMed ID: 26620281
[TBL] [Abstract][Full Text] [Related]
9. Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators.
Brocklehurst KJ; Payne VA; Davies RA; Carroll D; Vertigan HL; Wightman HJ; Aiston S; Waddell ID; Leighton B; Coghlan MP; Agius L
Diabetes; 2004 Mar; 53(3):535-41. PubMed ID: 14988235
[TBL] [Abstract][Full Text] [Related]
10. Lack of glucokinase regulatory protein expression may contribute to low glucokinase activity in feline liver.
Hiskett EK; Suwitheechon OU; Lindbloom-Hawley S; Boyle DL; Schermerhorn T
Vet Res Commun; 2009 Mar; 33(3):227-40. PubMed ID: 18780155
[TBL] [Abstract][Full Text] [Related]
11. Insulin-receptor substrate-2 (irs-2) is required for maintaining glucokinase and glucokinase regulatory protein expression in mouse liver.
Roncero I; Alvarez E; Acosta C; Sanz C; Barrio P; Hurtado-Carneiro V; Burks D; Blázquez E
PLoS One; 2013; 8(4):e58797. PubMed ID: 23560040
[TBL] [Abstract][Full Text] [Related]
12. Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations.
Heredia VV; Carlson TJ; Garcia E; Sun S
J Biol Chem; 2006 Dec; 281(52):40201-7. PubMed ID: 17082186
[TBL] [Abstract][Full Text] [Related]
13. Mutational analysis of allosteric activation and inhibition of glucokinase.
Zelent B; Odili S; Buettger C; Zelent DK; Chen P; Fenner D; Bass J; Stanley C; Laberge M; Vanderkooi JM; Sarabu R; Grimsby J; Matschinsky FM
Biochem J; 2011 Dec; 440(2):203-15. PubMed ID: 21831042
[TBL] [Abstract][Full Text] [Related]
14. Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
Lloyd DJ; St Jean DJ; Kurzeja RJ; Wahl RC; Michelsen K; Cupples R; Chen M; Wu J; Sivits G; Helmering J; Komorowski R; Ashton KS; Pennington LD; Fotsch C; Vazir M; Chen K; Chmait S; Zhang J; Liu L; Norman MH; Andrews KL; Bartberger MD; Van G; Galbreath EJ; Vonderfecht SL; Wang M; Jordan SR; Véniant MM; Hale C
Nature; 2013 Dec; 504(7480):437-40. PubMed ID: 24226772
[TBL] [Abstract][Full Text] [Related]
15. Recent Updates on Glucokinase Activators and Glucokinase Regulatory Protein Disrupters for the Treatment of Type 2 Diabetes Mellitus.
Kaushik A; Kaushik M
Curr Diabetes Rev; 2019; 15(3):205-212. PubMed ID: 30039763
[TBL] [Abstract][Full Text] [Related]
16. Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase.
de la Iglesia N; Veiga-da-Cunha M; Van Schaftingen E; Guinovart JJ; Ferrer JC
FEBS Lett; 1999 Aug; 456(2):332-8. PubMed ID: 10456334
[TBL] [Abstract][Full Text] [Related]
17. Molecular targeting of the GK-GKRP pathway in diabetes.
Hale C; Lloyd DJ; Pellacani A; Véniant MM
Expert Opin Ther Targets; 2015 Jan; 19(1):129-39. PubMed ID: 25324018
[TBL] [Abstract][Full Text] [Related]
18. Glucokinase and glucokinase regulatory proteins are functionally coexpressed before birth in the rat brain.
Roncero I; Sanz C; Alvarez E; Vázquez P; Barrio PA; Blázquez E
J Neuroendocrinol; 2009 Dec; 21(12):973-81. PubMed ID: 19807849
[TBL] [Abstract][Full Text] [Related]
19. Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.
Shiota C; Coffey J; Grimsby J; Grippo JF; Magnuson MA
J Biol Chem; 1999 Dec; 274(52):37125-30. PubMed ID: 10601273
[TBL] [Abstract][Full Text] [Related]
20. Glucose modulation of glucokinase activation by small molecules.
Ralph EC; Thomson J; Almaden J; Sun S
Biochemistry; 2008 Apr; 47(17):5028-36. PubMed ID: 18370405
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
