These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

685 related articles for article (PubMed ID: 18809732)

  • 1. Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model.
    Poirier A; Lavé T; Portmann R; Brun ME; Senner F; Kansy M; Grimm HP; Funk C
    Drug Metab Dispos; 2008 Dec; 36(12):2434-44. PubMed ID: 18809732
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.
    Poirier A; Funk C; Scherrmann JM; Lavé T
    Mol Pharm; 2009; 6(6):1716-33. PubMed ID: 19739673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
    Noé J; Portmann R; Brun ME; Funk C
    Drug Metab Dispos; 2007 Aug; 35(8):1308-14. PubMed ID: 17470528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prediction of pharmacokinetic profile of valsartan in humans based on in vitro uptake-transport data.
    Poirier A; Cascais AC; Funk C; Lavé T
    Chem Biodivers; 2009 Nov; 6(11):1975-87. PubMed ID: 19937834
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic determinants of hepatic clearance: plasma protein binding and hepatic uptake.
    Baker M; Parton T
    Xenobiotica; 2007; 37(10-11):1110-34. PubMed ID: 17968739
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Decrease in intracellular concentration causes the shift in Km value of efflux pump substrates.
    Korjamo T; Kemiläinen H; Heikkinen AT; Mönkkönen J
    Drug Metab Dispos; 2007 Sep; 35(9):1574-9. PubMed ID: 17548462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation of transporter-mediated hepatic uptake in a non-radioactive high-throughput assay: a study of kinetics, species difference and plasma protein effect.
    Li L; Nouraldeen A; Wilson AG
    Xenobiotica; 2013 Mar; 43(3):253-62. PubMed ID: 22928802
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Estimating human drug oral absorption kinetics from Caco-2 permeability using an absorption-disposition model: model development and evaluation and derivation of analytical solutions for k(a) and F(a).
    Usansky HH; Sinko PJ
    J Pharmacol Exp Ther; 2005 Jul; 314(1):391-9. PubMed ID: 15833900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prediction of human pharmacokinetics - renal metabolic and excretion clearance.
    Fagerholm U
    J Pharm Pharmacol; 2007 Nov; 59(11):1463-71. PubMed ID: 17976256
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacokinetic drug interaction between fexofenadine and fluvastatin mediated by organic anion-transporting polypeptides in rats.
    Qiang F; Lee BJ; Lee W; Han HK
    Eur J Pharm Sci; 2009 Jun; 37(3-4):413-7. PubMed ID: 19428223
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prediction of the pharmacokinetics of atorvastatin, cerivastatin, and indomethacin using kinetic models applied to isolated rat hepatocytes.
    Paine SW; Parker AJ; Gardiner P; Webborn PJ; Riley RJ
    Drug Metab Dispos; 2008 Jul; 36(7):1365-74. PubMed ID: 18426955
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prediction of human pharmacokinetics--gastrointestinal absorption.
    Fagerholm U
    J Pharm Pharmacol; 2007 Jul; 59(7):905-16. PubMed ID: 17637184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.
    Jones HM; Barton HA; Lai Y; Bi YA; Kimoto E; Kempshall S; Tate SC; El-Kattan A; Houston JB; Galetin A; Fenner KS
    Drug Metab Dispos; 2012 May; 40(5):1007-17. PubMed ID: 22344703
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prediction of pharmacokinetic profile of valsartan in human based on in vitro uptake transport data.
    Poirier A; Cascais AC; Funk C; Lavé T
    J Pharmacokinet Pharmacodyn; 2009 Dec; 36(6):585-611. PubMed ID: 19936896
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.
    Nezasa K; Higaki K; Takeuchi M; Nakano M; Koike M
    Xenobiotica; 2003 Apr; 33(4):379-88. PubMed ID: 12745873
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Permeability, transport, and metabolism of solutes in Caco-2 cell monolayers: a theoretical study.
    Sun H; Pang KS
    Drug Metab Dispos; 2008 Jan; 36(1):102-23. PubMed ID: 17932224
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetic characterization of rat hepatic uptake of 16 actively transported drugs.
    Yabe Y; Galetin A; Houston JB
    Drug Metab Dispos; 2011 Oct; 39(10):1808-14. PubMed ID: 21730030
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.
    Tahara H; Kusuhara H; Maeda K; Koepsell H; Fuse E; Sugiyama Y
    Drug Metab Dispos; 2006 May; 34(5):743-7. PubMed ID: 16455804
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Simultaneous assessment of uptake and metabolism in rat hepatocytes: a comprehensive mechanistic model.
    Ménochet K; Kenworthy KE; Houston JB; Galetin A
    J Pharmacol Exp Ther; 2012 Apr; 341(1):2-15. PubMed ID: 22190645
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population.
    Sugano K
    Int J Pharm; 2009 May; 373(1-2):55-61. PubMed ID: 19429288
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.