400 related articles for article (PubMed ID: 18815706)
21. Coumarin-derived discodermolide analogues possessing equivalent antiproliferative activity to the natural product--a further simplification of the lactone region.
Shaw SJ; Menzella HG; Myles DC; Xian M; Smith AB
Org Biomol Chem; 2007 Sep; 5(17):2753-5. PubMed ID: 17700839
[TBL] [Abstract][Full Text] [Related]
22. Conception, synthesis, and biological evaluation of original discodermolide analogues.
de Lemos E; Agouridas E; Sorin G; Guerreiro A; Commerçon A; Pancrazi A; Betzer JF; Lannou MI; Ardisson J
Chemistry; 2011 Aug; 17(36):10123-34. PubMed ID: 21793059
[TBL] [Abstract][Full Text] [Related]
23. Marine natural products: synthetic aspects.
Morris JC; Phillips AJ
Nat Prod Rep; 2008 Feb; 25(1):95-117. PubMed ID: 18250898
[TBL] [Abstract][Full Text] [Related]
24. (+)-discodermolide: a marine natural product against cancer.
De Souza MV
ScientificWorldJournal; 2004 Jun; 4():415-36. PubMed ID: 15243683
[TBL] [Abstract][Full Text] [Related]
25. Marine natural products: synthetic aspects.
Morris JC; Nicholas GM; Phillips AJ
Nat Prod Rep; 2007 Feb; 24(1):87-108. PubMed ID: 17268608
[TBL] [Abstract][Full Text] [Related]
26. The structure activity relationship of discodermolide analogues.
Shaw SJ
Mini Rev Med Chem; 2008 Mar; 8(3):276-84. PubMed ID: 18336347
[TBL] [Abstract][Full Text] [Related]
27. The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.
Kowalski RJ; Giannakakou P; Gunasekera SP; Longley RE; Day BW; Hamel E
Mol Pharmacol; 1997 Oct; 52(4):613-22. PubMed ID: 9380024
[TBL] [Abstract][Full Text] [Related]
28. Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells.
Honore S; Kamath K; Braguer D; Horwitz SB; Wilson L; Briand C; Jordan MA
Cancer Res; 2004 Jul; 64(14):4957-64. PubMed ID: 15256469
[TBL] [Abstract][Full Text] [Related]
29. Toward understanding how the lactone moiety of discodermolide affects activity.
Shaw SJ; Sundermann KF; Burlingame MA; Myles DC; Freeze BS; Xian M; Brouard I; Smith AB
J Am Chem Soc; 2005 May; 127(18):6532-3. PubMed ID: 15869264
[TBL] [Abstract][Full Text] [Related]
30. alpha-Oxygenated crotyltitanium and dyotropic rearrangement in the total synthesis of discodermolide.
de Lemos E; Porée FH; Commerçon A; Betzer JF; Pancrazi A; Ardisson J
Angew Chem Int Ed Engl; 2007; 46(11):1917-21. PubMed ID: 17262876
[No Abstract] [Full Text] [Related]
31. Total synthesis of (+)-discodermolide: a highly convergent fourth-generation approach.
Smith AB; Freeze BS; Xian M; Hirose T
Org Lett; 2005 Apr; 7(9):1825-8. PubMed ID: 15844916
[TBL] [Abstract][Full Text] [Related]
32. Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol.
ter Haar E; Kowalski RJ; Hamel E; Lin CM; Longley RE; Gunasekera SP; Rosenkranz HS; Day BW
Biochemistry; 1996 Jan; 35(1):243-50. PubMed ID: 8555181
[TBL] [Abstract][Full Text] [Related]
33. A second-generation total synthesis of (+)-discodermolide: the development of a practical route using solely substrate-based stereocontrol.
Paterson I; Delgado O; Florence GJ; Lyothier I; O'Brien M; Scott JP; Sereinig N
J Org Chem; 2005 Jan; 70(1):150-60. PubMed ID: 15624917
[TBL] [Abstract][Full Text] [Related]
34. Marine cytotoxic macrolides haterumalides and biselides, and related natural products.
Kigoshi H; Hayakawa I
Chem Rec; 2007; 7(4):254-64. PubMed ID: 17663448
[TBL] [Abstract][Full Text] [Related]
35. Simplified discodermolide analogues: synthesis and biological evaluation of 4-epi-7-dehydroxy-14,16-didemethyl-(+)-discodermolides as microtubule-stabilizing agents.
Choy N; Shin Y; Nguyen PQ; Curran DP; Balachandran R; Madiraju C; Day BW
J Med Chem; 2003 Jul; 46(14):2846-64. PubMed ID: 12825928
[TBL] [Abstract][Full Text] [Related]
36. Crotylsilane reagents in the synthesis of complex polyketide natural products: total synthesis of (+)-discodermolide.
Arefolov A; Panek JS
J Am Chem Soc; 2005 Apr; 127(15):5596-603. PubMed ID: 15826198
[TBL] [Abstract][Full Text] [Related]
37. A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin.
Xia S; Kenesky CS; Rucker PV; Smith AB; Orr GA; Horwitz SB
Biochemistry; 2006 Oct; 45(39):11762-75. PubMed ID: 17002277
[TBL] [Abstract][Full Text] [Related]
38. Discodermolide analogues as the chemical component of combination bacteriolytic therapy.
Smith AB; Freeze BS; LaMarche MJ; Sager J; Kinzler KW; Vogelstein B
Bioorg Med Chem Lett; 2005 Aug; 15(15):3623-6. PubMed ID: 15979874
[TBL] [Abstract][Full Text] [Related]
39. Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1-dependent.
Chao SK; Lin J; Brouwer-Visser J; Smith AB; Horwitz SB; McDaid HM
Proc Natl Acad Sci U S A; 2011 Jan; 108(1):391-6. PubMed ID: 21173253
[TBL] [Abstract][Full Text] [Related]
40. Cell-based and biochemical structure-activity analyses of analogs of the microtubule stabilizer dictyostatin.
Raccor BS; Vogt A; Sikorski RP; Madiraju C; Balachandran R; Montgomery K; Shin Y; Fukui Y; Jung WH; Curran DP; Day BW
Mol Pharmacol; 2008 Mar; 73(3):718-26. PubMed ID: 18073274
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
