175 related articles for article (PubMed ID: 18816529)
1. Pyridyl derivatives of benzaldehyde as potential antisickling agents.
Nnamani IN; Joshi GS; Danso-Danquah R; Abdulmalik O; Asakura T; Abraham DJ; Safo MK
Chem Biodivers; 2008 Sep; 5(9):1762-9. PubMed ID: 18816529
[TBL] [Abstract][Full Text] [Related]
2. Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease.
Pagare PP; Ghatge MS; Musayev FN; Deshpande TM; Chen Q; Braxton C; Kim S; Venitz J; Zhang Y; Abdulmalik O; Safo MK
Bioorg Med Chem; 2018 May; 26(9):2530-2538. PubMed ID: 29655608
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds.
Safo MK; Abdulmalik O; Danso-Danquah R; Burnett JC; Nokuri S; Joshi GS; Musayev FN; Asakura T; Abraham DJ
J Med Chem; 2004 Sep; 47(19):4665-76. PubMed ID: 15341482
[TBL] [Abstract][Full Text] [Related]
4. Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin.
Abdulmalik O; Ghatge MS; Musayev FN; Parikh A; Chen Q; Yang J; Nnamani I; Danso-Danquah R; Eseonu DN; Asakura T; Abraham DJ; Venitz J; Safo MK
Acta Crystallogr D Biol Crystallogr; 2011 Nov; 67(Pt 11):920-8. PubMed ID: 22101818
[TBL] [Abstract][Full Text] [Related]
5. Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation.
Deshpande TM; Pagare PP; Ghatge MS; Chen Q; Musayev FN; Venitz J; Zhang Y; Abdulmalik O; Safo MK
Acta Crystallogr D Struct Biol; 2018 Oct; 74(Pt 10):956-964. PubMed ID: 30289405
[TBL] [Abstract][Full Text] [Related]
6. Exploration of Structure-Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents.
Pagare PP; Ghatge MS; Chen Q; Musayev FN; Venitz J; Abdulmalik O; Zhang Y; Safo MK
J Med Chem; 2020 Dec; 63(23):14724-14739. PubMed ID: 33205981
[TBL] [Abstract][Full Text] [Related]
7. Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin.
Omar AM; Mahran MA; Ghatge MS; Bamane FH; Ahmed MH; El-Araby ME; Abdulmalik O; Safo MK
Molecules; 2016 Aug; 21(8):. PubMed ID: 27529207
[TBL] [Abstract][Full Text] [Related]
8. Substituted benzaldehydes designed to increase the oxygen affinity of human haemoglobin and inhibit the sickling of sickle erythrocytes.
Beddell CR; Goodford PJ; Kneen G; White RD; Wilkinson S; Wootton R
Br J Pharmacol; 1984 Jun; 82(2):397-407. PubMed ID: 6733364
[TBL] [Abstract][Full Text] [Related]
9. An Investigation of Structure-Activity Relationships of Azolylacryloyl Derivatives Yielded Potent and Long-Acting Hemoglobin Modulators for Reversing Erythrocyte Sickling.
Omar AM; Abdulmalik O; Ghatge MS; Muhammad YA; Paredes SD; El-Araby ME; Safo MK
Biomolecules; 2020 Nov; 10(11):. PubMed ID: 33147875
[TBL] [Abstract][Full Text] [Related]
10. Identification of a novel class of covalent modifiers of hemoglobin as potential antisickling agents.
Omar AM; Mahran MA; Ghatge MS; Chowdhury N; Bamane FH; El-Araby ME; Abdulmalik O; Safo MK
Org Biomol Chem; 2015 Jun; 13(22):6353-70. PubMed ID: 25974708
[TBL] [Abstract][Full Text] [Related]
11. Biological activity of liposomal vanillin.
Castan L; Del Toro G; Fernández AA; González M; Ortíz E; Lobo D
J Med Food; 2013 Jun; 16(6):551-7. PubMed ID: 23767864
[TBL] [Abstract][Full Text] [Related]
12. QSAR and kinetics of the inhibition of benzaldehyde derivatives against Sacrophaga neobelliaria phenoloxidase.
Li W; Kubo I
Bioorg Med Chem; 2004 Feb; 12(4):701-13. PubMed ID: 14759731
[TBL] [Abstract][Full Text] [Related]
13. Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease.
Xu GG; Pagare PP; Ghatge MS; Safo RP; Gazi A; Chen Q; David T; Alabbas AB; Musayev FN; Venitz J; Zhang Y; Safo MK; Abdulmalik O
Mol Pharm; 2017 Oct; 14(10):3499-3511. PubMed ID: 28858508
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and anticancer activity of benzyloxybenzaldehyde derivatives against HL-60 cells.
Lin CF; Yang JS; Chang CY; Kuo SC; Lee MR; Huang LJ
Bioorg Med Chem; 2005 Mar; 13(5):1537-44. PubMed ID: 15698770
[TBL] [Abstract][Full Text] [Related]
15. Structure-function analysis of the vanillin molecule and its antifungal properties.
Fitzgerald DJ; Stratford M; Gasson MJ; Narbad A
J Agric Food Chem; 2005 Mar; 53(5):1769-75. PubMed ID: 15740072
[TBL] [Abstract][Full Text] [Related]
16. Quantitative structure-activity relationship of phenoxy and benzyloxy acid derivatives as antisickling agents.
Mahran MA
Boll Chim Farm; 2000; 139(2):73-80. PubMed ID: 10920532
[TBL] [Abstract][Full Text] [Related]
17. A structure-guided approach to ameliorate sickle cell disease.
Richter-Addo GB
Acta Crystallogr D Struct Biol; 2018 Nov; 74(Pt 11):1039-1040. PubMed ID: 30387762
[No Abstract] [Full Text] [Related]
18. Allosteric modifiers of hemoglobin. 1. Design, synthesis, testing, and structure-allosteric activity relationship of novel hemoglobin oxygen affinity decreasing agents.
Randad RS; Mahran MA; Mehanna AS; Abraham DJ
J Med Chem; 1991 Feb; 34(2):752-7. PubMed ID: 1995897
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and antienteroviral activity of a series of novel, oxime ether-containing pyridyl imidazolidinones.
Chern JH; Lee CC; Chang CS; Lee YC; Tai CL; Lin YT; Shia KS; Lee CY; Shih SR
Bioorg Med Chem Lett; 2004 Oct; 14(20):5051-6. PubMed ID: 15380197
[TBL] [Abstract][Full Text] [Related]
20. Methyl 2-(2-(4-formylphenoxy)acetamido)-2-substituted acetate derivatives: a new class of acetylcholinesterase inhibitors.
Wen H; Zhou Y; Lin C; Ge H; Ma L; Wang Z; Peng W; Song H
Bioorg Med Chem Lett; 2007 Apr; 17(8):2123-5. PubMed ID: 17317172
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]