BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 18817363)

  • 1. Structure-activity relationships in 1,4-benzodioxan-related compounds. 9. From 1,4-benzodioxane to 1,4-dioxane ring as a promising template of novel alpha1D-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents.
    Quaglia W; Piergentili A; Del Bello F; Farande Y; Giannella M; Pigini M; Rafaiani G; Carrieri A; Amantini C; Lucciarini R; Santoni G; Poggesi E; Leonardi A
    J Med Chem; 2008 Oct; 51(20):6359-70. PubMed ID: 18817363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. WB 4101-related compounds. 2. Role of the ethylene chain separating amine and phenoxy units on the affinity for alpha(1)-adrenoreceptor subtypes and 5-HT(1A) receptors.
    Bolognesi ML; Budriesi R; Cavalli A; Chiarini A; Gotti R; Leonardi A; Minarini A; Poggesi E; Recanatini M; Rosini M; Tumiatti V; Melchiorre C
    J Med Chem; 1999 Oct; 42(20):4214-24. PubMed ID: 10514291
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships in 1,4-benzodioxan-related compounds. 6. Role of the dioxane unit on selectivity for alpha(1)-adrenoreceptor subtypes.
    Quaglia W; Pigini M; Piergentili A; Giannella M; Marucci G; Poggesi E; Leonardi A; Melchiorre C
    J Med Chem; 1999 Jul; 42(15):2961-8. PubMed ID: 10425105
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships in 1,4-benzodioxan-related compounds. 11. (1) reversed enantioselectivity of 1,4-dioxane derivatives in α1-adrenergic and 5-HT1A receptor binding sites recognition.
    Bonifazi A; Piergentili A; Del Bello F; Farande Y; Giannella M; Pigini M; Amantini C; Nabissi M; Farfariello V; Santoni G; Poggesi E; Leonardi A; Menegon S; Quaglia W
    J Med Chem; 2013 Jan; 56(2):584-8. PubMed ID: 23252794
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes.
    Quaglia W; Pigini M; Piergentili A; Giannella M; Gentili F; Marucci G; Carrieri A; Carotti A; Poggesi E; Leonardi A; Melchiorre C
    J Med Chem; 2002 Apr; 45(8):1633-43. PubMed ID: 11931617
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chemical manipulations on the 1,4-dioxane ring of 5-HT
    Del Bello F; Bonifazi A; Giorgioni G; Quaglia W; Amantini C; Morelli MB; Santoni G; Battiti FO; Vistoli G; Cilia A; Piergentili A
    Eur J Med Chem; 2019 Apr; 168():461-473. PubMed ID: 30844609
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist.
    Fumagalli L; Pallavicini M; Budriesi R; Gobbi M; Straniero V; Zagami M; Chiodini G; Bolchi C; Chiarini A; Micucci M; Valoti E
    Eur J Med Chem; 2012 Dec; 58():184-91. PubMed ID: 23124215
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.
    Franchini S; Prandi A; Baraldi A; Sorbi C; Tait A; Buccioni M; Marucci G; Cilia A; Pirona L; Fossa P; Cichero E; Brasili L
    Eur J Med Chem; 2010 Sep; 45(9):3740-51. PubMed ID: 20605276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prazosin-related compounds. Effect of transforming the piperazinylquinazoline moiety into an aminomethyltetrahydroacridine system on the affinity for alpha1-adrenoreceptors.
    Rosini M; Antonello A; Cavalli A; Bolognesi ML; Minarini A; Marucci G; Poggesi E; Leonardi A; Melchiorre C
    J Med Chem; 2003 Nov; 46(23):4895-903. PubMed ID: 14584940
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands.
    Tait A; Luppi A; Franchini S; Preziosi E; Parenti C; Buccioni M; Marucci G; Leonardi A; Poggesi E; Brasili L
    Bioorg Med Chem Lett; 2005 Feb; 15(4):1185-8. PubMed ID: 15686938
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT
    Del Bello F; Bonifazi A; Giannella M; Giorgioni G; Piergentili A; Petrelli R; Cifani C; Micioni Di Bonaventura MV; Keck TM; Mazzolari A; Vistoli G; Cilia A; Poggesi E; Matucci R; Quaglia W
    Eur J Med Chem; 2017 Jan; 125():233-244. PubMed ID: 27662034
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha 1d adrenergic receptor.
    Leonardi A; Barlocco D; Montesano F; Cignarella G; Motta G; Testa R; Poggesi E; Seeber M; De Benedetti PG; Fanelli F
    J Med Chem; 2004 Apr; 47(8):1900-18. PubMed ID: 15055991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human α1-adrenoceptor subtype selectivity of substituted homobivalent 4-aminoquinolines.
    Chen J; Campbell AP; Urmi KF; Wakelin LP; Denny WA; Griffith R; Finch AM
    Bioorg Med Chem; 2014 Nov; 22(21):5910-6. PubMed ID: 25288493
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships in 1,4-benzodioxan-related compounds. 10. Novel α1-adrenoreceptor antagonists related to openphendioxan: synthesis, biological evaluation, and α1d computational study.
    Carrieri A; Piergentili A; Del Bello F; Giannella M; Pigini M; Leonardi A; Fanelli F; Quaglia W
    Bioorg Med Chem; 2010 Oct; 18(19):7065-77. PubMed ID: 20801662
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.
    Prandi A; Franchini S; Manasieva LI; Fossa P; Cichero E; Marucci G; Buccioni M; Cilia A; Pirona L; Brasili L
    J Med Chem; 2012 Jan; 55(1):23-36. PubMed ID: 22145629
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigation of the role of the serotonergic activity of certain subtype-selective alpha1A antagonists in the relaxant effect on the pregnant rat uterus in vitro.
    Mihályi A; Ducza E; Gáspár R; Falkay G
    Mol Hum Reprod; 2003 Aug; 9(8):475-80. PubMed ID: 12837924
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective α
    Sakauchi N; Furukawa H; Shirai J; Sato A; Kuno H; Saikawa R; Yoshida M
    Eur J Med Chem; 2017 Oct; 139():114-127. PubMed ID: 28800452
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of alpha 1 antagonist WB-4101.
    Bolchi C; Catalano P; Fumagalli L; Gobbi M; Pallavicini M; Pedretti A; Villa L; Vistoli G; Valoti E
    Bioorg Med Chem; 2004 Sep; 12(18):4937-51. PubMed ID: 15336273
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alpha1A-adrenergic receptors are functionally expressed by a subpopulation of cornu ammonis 1 interneurons in rat hippocampus.
    Hillman KL; Doze VA; Porter JE
    J Pharmacol Exp Ther; 2007 Jun; 321(3):1062-8. PubMed ID: 17337632
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro".
    Colciago A; Mornati O; Ferri N; Castelnovo LF; Fumagalli L; Bolchi C; Pallavicini M; Valoti E; Negri-Cesi P
    Pharmacol Res; 2016 Jan; 103():215-26. PubMed ID: 26621245
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.