686 related articles for article (PubMed ID: 18817800)
1. Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro.
Dykens JA; Jamieson J; Marroquin L; Nadanaciva S; Billis PA; Will Y
Toxicol Appl Pharmacol; 2008 Dec; 233(2):203-10. PubMed ID: 18817800
[TBL] [Abstract][Full Text] [Related]
2. Aroclor 1254 induced cytotoxicity and mitochondrial dysfunction in isolated rat hepatocytes.
Aly HA; Domènech O
Toxicology; 2009 Aug; 262(3):175-83. PubMed ID: 19486918
[TBL] [Abstract][Full Text] [Related]
3. Comparison of potential risks of lactic acidosis induction by biguanides in rats.
Bando K; Ochiai S; Kunimatsu T; Deguchi J; Kimura J; Funabashi H; Seki T
Regul Toxicol Pharmacol; 2010 Oct; 58(1):155-60. PubMed ID: 20488215
[TBL] [Abstract][Full Text] [Related]
4. High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes.
Igoudjil A; Massart J; Begriche K; Descatoire V; Robin MA; Fromenty B
Toxicol In Vitro; 2008 Jun; 22(4):887-98. PubMed ID: 18299183
[TBL] [Abstract][Full Text] [Related]
5. Circumventing the Crabtree effect: replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants.
Marroquin LD; Hynes J; Dykens JA; Jamieson JD; Will Y
Toxicol Sci; 2007 Jun; 97(2):539-47. PubMed ID: 17361016
[TBL] [Abstract][Full Text] [Related]
6. Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes.
Detaille D; Sanchez C; Sanz N; Lopez-Novoa JM; Leverve X; El-Mir MY
Life Sci; 2008 May; 82(21-22):1070-6. PubMed ID: 18448125
[TBL] [Abstract][Full Text] [Related]
7. In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone.
Dykens JA; Jamieson JD; Marroquin LD; Nadanaciva S; Xu JJ; Dunn MC; Smith AR; Will Y
Toxicol Sci; 2008 Jun; 103(2):335-45. PubMed ID: 18344530
[TBL] [Abstract][Full Text] [Related]
8. Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin.
Wang DS; Kusuhara H; Kato Y; Jonker JW; Schinkel AH; Sugiyama Y
Mol Pharmacol; 2003 Apr; 63(4):844-8. PubMed ID: 12644585
[TBL] [Abstract][Full Text] [Related]
9. A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes.
Sogame Y; Kitamura A; Yabuki M; Komuro S
Biopharm Drug Dispos; 2009 Nov; 30(8):476-84. PubMed ID: 19768675
[TBL] [Abstract][Full Text] [Related]
10. High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening.
O'Brien PJ; Irwin W; Diaz D; Howard-Cofield E; Krejsa CM; Slaughter MR; Gao B; Kaludercic N; Angeline A; Bernardi P; Brain P; Hougham C
Arch Toxicol; 2006 Sep; 80(9):580-604. PubMed ID: 16598496
[TBL] [Abstract][Full Text] [Related]
11. The role of oxidative stress, impaired glycolysis and mitochondrial respiratory redox failure in the cytotoxic effects of 6-hydroxydopamine in vitro.
Mazzio EA; Reams RR; Soliman KF
Brain Res; 2004 Apr; 1004(1-2):29-44. PubMed ID: 15033417
[TBL] [Abstract][Full Text] [Related]
12. Usnic acid-induced necrosis of cultured mouse hepatocytes: inhibition of mitochondrial function and oxidative stress.
Han D; Matsumaru K; Rettori D; Kaplowitz N
Biochem Pharmacol; 2004 Feb; 67(3):439-51. PubMed ID: 15037196
[TBL] [Abstract][Full Text] [Related]
13. Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition.
Piel S; Ehinger JK; Elmér E; Hansson MJ
Acta Physiol (Oxf); 2015 Jan; 213(1):171-80. PubMed ID: 24801139
[TBL] [Abstract][Full Text] [Related]
14. Toxicity of alpidem, a peripheral benzodiazepine receptor ligand, but not zolpidem, in rat hepatocytes: role of mitochondrial permeability transition and metabolic activation.
Berson A; Descatoire V; Sutton A; Fau D; Maulny B; Vadrot N; Feldmann G; Berthon B; Tordjmann T; Pessayre D
J Pharmacol Exp Ther; 2001 Nov; 299(2):793-800. PubMed ID: 11602696
[TBL] [Abstract][Full Text] [Related]
15. Glycyrrhizic acid modulates t-BHP induced apoptosis in primary rat hepatocytes.
Tripathi M; Singh BK; Kakkar P
Food Chem Toxicol; 2009 Feb; 47(2):339-47. PubMed ID: 19084568
[TBL] [Abstract][Full Text] [Related]
16. Roles of reactive oxygen species and MAP kinases in the primary rat hepatocytes death induced by toosendanin.
Zhang Y; Qi X; Gong L; Li Y; Liu L; Xue X; Xiao Y; Wu X; Ren J
Toxicology; 2008 Jul; 249(1):62-8. PubMed ID: 18499325
[TBL] [Abstract][Full Text] [Related]
17. Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.
Hinke SA; Martens GA; Cai Y; Finsi J; Heimberg H; Pipeleers D; Van de Casteele M
Br J Pharmacol; 2007 Apr; 150(8):1031-43. PubMed ID: 17339833
[TBL] [Abstract][Full Text] [Related]
18. N-acetylcysteine, coenzyme Q10 and superoxide dismutase mimetic prevent mitochondrial cell dysfunction and cell death induced by d-galactosamine in primary culture of human hepatocytes.
González R; Ferrín G; Hidalgo AB; Ranchal I; López-Cillero P; Santos-Gónzalez M; López-Lluch G; Briceño J; Gómez MA; Poyato A; Villalba JM; Navas P; de la Mata M; Muntané J
Chem Biol Interact; 2009 Sep; 181(1):95-106. PubMed ID: 19523936
[TBL] [Abstract][Full Text] [Related]
19. Glutathione mediated reductive activation and mitochondrial dysfunction play key roles in lithium induced oxidative stress and cytotoxicity in liver.
Eskandari MR; Fard JK; Hosseini MJ; Pourahmad J
Biometals; 2012 Oct; 25(5):863-73. PubMed ID: 22588640
[TBL] [Abstract][Full Text] [Related]
20. Hepatocellular toxicity of kava leaf and root extracts.
Lüde S; Török M; Dieterle S; Jäggi R; Büter KB; Krähenbühl S
Phytomedicine; 2008 Jan; 15(1-2):120-31. PubMed ID: 18055189
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
